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prof. dr. P.W.B. (Patrick W.B.) Derksen

prof. dr. P.W.B. (Patrick W.B.) Derksen

Full Professor

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Research Output (39)

Atlas of Lobular Breast Cancer Models:Challenges and Strategic Directions

Sflomos George, Schipper Koen, Koorman Thijs, Fitzpatrick Amanda, Oesterreich Steffi, Lee Adrian V, Jonkers Jos, Brunton Valerie G, Christgen Matthias, Isacke Clare, Derksen Patrick W B, Brisken Cathrin 1 Nov 2021, In: Cancers. 13

Lobular breast cancer:Histomorphology and different concepts of a special spectrum of tumors

Christgen Matthias, Cserni Gábor, Floris Giuseppe, Marchio Caterina, Djerroudi Lounes, Kreipe Hans, Derksen Patrick W.B., Vincent-Salomon Anne 1 Aug 2021, In: Cancers. 13 , p. 1-34 34 p.

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

Vervoort Stephin J., de Jong Olivier G., Guy Roukens M., Frederiks Cynthia L., Vermeulen Jeroen F., Lourenço Ana Rita, Bella Laura, Vidakovic Ana Tufegdzic, Sandoval José L., Moelans Cathy, van Amersfoort Miranda, Dallman Margaret J., Bruna Alejandra, Caldas Carlos, Nieuwenhuis Edward, van der Wall Elsken, Derksen Patrick, van Diest Paul, Verhaar Marianne C., Lam Eric W.F., Mokry Michal, Coffer Paul J. 3 Dec 2018, In: eLife. 7

E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer

Teo Katy, Gómez-Cuadrado Laura, Tenhagen Milou, Byron Adam, Rätze Max, van Amersfoort Miranda, Renes Jojanneke, Strengman Eric, Mandoli Amit, Singh Abhishek A., Martens Joost H., Stunnenberg Hendrik G., van Diest Paul J., Brunton Valerie G., Derksen Patrick W.B. 1 Dec 2018, In: Scientific Reports. 8

Re-inforcing the cell death army in the fight against breast cancer

Oudenaarden Clara R L, van de Ven Robert A H, Derksen Patrick W B 23 Aug 2018, In: Journal of Cell Science. 131

αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer

de Groot Jolien S., Ratze Max A.K., van Amersfoort Miranda, Eisemann Tanja, Vlug Eva J., Niklaas Mijanou T., Chin Suet Feung, Caldas Carlos, van Diest Paul J., Jonkers Jos, de Rooij Johan, Derksen Patrick W.B. 1 Aug 2018, In: Journal of Pathology. 245 , p. 456-467 12 p.

FOXO transcription factors both suppress and support breast cancer progression

Hornsveld Marten, Smits Lydia M.M., Meerlo Maaike, Van Amersfoort Miranda, Groot Koerkamp Marian J.A., van Leenen Dik, Kloet David E.A., Holstege Frank C.P., Derksen Patrick W.B., Burgering Boudewijn M.T., Dansen Tobias B. 1 May 2018, In: Cancer Research. 78 , p. 2356-2369 14 p.

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Bajrami Ilirjana, Marlow Rebecca, van de Ven Marieke, Brough Rachel, Pemberton Helen N, Frankum Jessica, Song Feifei, Rafiq Rumana, Konde Asha, Krastev Dragomir B, Menon Malini, Campbell James, Gulati Aditi, Kumar Rahul, Pettitt Stephen J, Gurden Mark D, Cardenosa Marta Llorca, Chong Irene, Gazinska Patrycja, Wallberg Fredrik, Sawyer Elinor J, Martin Lesley-Ann, Dowsett Mitch, Linardopoulos Spiros, Natrajan Rachael, Ryan Colm J, Derksen Patrick W B, Jonkers Jos, Tutt Andrew N J, Ashworth Alan, Lord Christopher J Apr 2018, In: Cancer Discovery. 8 , p. 498-515 18 p.

Prophylaxis of hereditary breast cancer

de Groot Jolien S., van Diest Paul J., Derksen Patrick W.B. 1 Dec 2017, In: Aging. 9 , p. 2453-2454 2 p.

Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice

de Groot Jolien S, van Diest Paul J, van Amersfoort Miranda, Vlug Eva J., Pan Xiaojuan, ter Hoeve Natalie D., Rosing Hilde, Beijnen Jos H, Youssef Sameh A., De Bruin Alain, Jonkers Jos, van der Wall Elsken, Derksen Patrick W B 15 Jun 2017, In: Oncotarget. 8 , p. 60750-60763 14 p.

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