dr. J. (Julia) Drylewicz

dr. J. (Julia) Drylewicz

Assistant Professor
dr. J. (Julia) Drylewicz
  • Center for Translational Immunology (CTI) Computational Immunology Core

Research Programs

Infection & Immunity



Julia Drylewicz is an Assistant Professor within the Computational Immunology Core of the Center for Translational Immunology (CTI) of the UMC Utrecht focusing on biomarkers discovery and bringing methodological support to researchers from the design of a project to its publication.

Since 2014, she collaborates with many groups on multidisciplinary projects within the CTI and aim at closing the gap between experimental and theoretical work by using biostatistics, bioinformatics and computational approaches. Some of her most recent projects involve modeling cell homeostasis in human, defining the optimal time of maternal vaccination for RSV infection, determining endotypes of atopic dermatitis patients based on serum biomarkers measured by Luminex and analyses of Olink data.  

She was trained in Biostatistics and Epidemiology at Bordeaux School of Public Health (ISPED, France) and graduated in Biomathematics from Paris V University (France) in 2006. She obtained her PhD in biostatistics at Bordeaux University (France) in 2009. From 2010 till 2014, she performed postdoctoral research in computational and quantitative immunology under the supervision of José Borghans in the Department of Immunology at the UMC Utrecht and collaborated with Rob de Boer in the Utrecht Center for Quantitative Immunology at Utrecht University. Her research focused on quantifying cell dynamics in health and disease using mathematical modeling to analyze stable-isotope labeling experiments.

Research Output (59)

Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

van Eijs Mick J.M., ter Linde José J.M., Baars Matthijs J.D., Amini Mojtaba, Laclé Miangela M., Brand Eelco C., Delemarre Eveline M., Drylewicz Julia, Nierkens Stefan, Verheijden Rik J., Oldenburg Bas, Vercoulen Yvonne, Suijkerbuijk Karijn P.M., van Wijk Femke 20 Oct 2023, In: iScience. 26

Biomarkers in atopic dermatitis

Bakker Daphne, de Bruin-Weller Marjolein, Drylewicz Julia, van Wijk Femke, Thijs Judith 2023, In: Journal of Allergy and Clinical Immunology. 151 , p. 1163-1168 6 p.

Clinical features and immune-related protein patterns of anti-MDA5 positive clinically amyopathic dermatomyositis Dutch patients

Hensgens Marjolein P.M., Delemarre Eveline M., Drylewicz Julia, Voortman Mareye, Krol Roline M., Dalm Virgil A.S.H., Miedema Jelle R., Wiertz Ivo, Grutters Jan, Limper Maarten, Nierkens Stefan, Leavis Helen L. 6 Oct 2022, In: Rheumatology (Oxford, England). 61 , p. 4087-4096 10 p.

A Network of Serum Proteins Predict the Need for Systemic Immunomodulatory Therapy at Diagnosis in Noninfectious Uveitis

Kuiper Jonas J W, Verhagen Fleurieke H, Hiddingh Sanne, Wennink Roos A W, Hansen Anna M, Casey Kerry A, Hoefer Imo E, Haitjema Saskia, Drylewicz Julia, Yakin Mehmet, Sen H Nida, Radstake Timothy R D J, de Boer Joke H Sep 2022, In: Ophthalmology science. 2 , p. 1-9

Turnover of Murine Cytomegalovirus-Expanded CD8<sup>+</sup> T Cells Is Similar to That of Memory Phenotype T Cells and Independent of the Magnitude of the Response

Baliu-Piqué Mariona, Drylewicz Julia, Zheng Xiaoyan, Borkner Lisa, Swain Arpit C., Otto Sigrid A., de Boer Rob J., Tesselaar Kiki, Cicin-Sain Luka, Borghans José A.M. 15 Feb 2022, In: Journal of immunology (Baltimore, Md. : 1950). 208 , p. 799-806 8 p.

Thrombosis pathways in COVID-19 vs. influenza-associated ARDS:a targeted proteomics approach

Rademaker Emma, Doorduijn Dennis J, Kusadasi Nuray, Maas Coen, Drylewicz Julia, Huisman Albert, Hoefer Imo E, Bonten Marc J M, Derde Lennie P G, Rooijakkers Suzan H M, Cremer Olaf L 12 Feb 2022, In: Journal of thrombosis and haemostasis : JTH. 20 , p. 1206-1212 7 p.

Unraveling heterogeneity in pediatric atopic dermatitis::identification of serum biomarker based patient clusters

Bakker D., de Graaf M., Nierkens S., Delemarre E., Knol E., van Wijk F., de Bruin-Weller M., Drylewicz J., Thijs J. Jan 2022, In: Journal of Investigative Dermatology. 149 , p. 125-134 10 p.

Patient-centered dupilumab dosing regimen leads to successful dose reduction in persistently controlled atopic dermatitis

Spekhorst Lotte S, Bakker Daphne, Drylewicz Julia, Rispens Theo, Loeff Floris, Boesjes Celeste M, Thijs Judith, Romeijn Geertruida L E, Loman Laura, Schuttelaar Marie-Louise, van Wijk Femke, de Graaf Marlies, de Bruin-Weller Marjolein S 2022, In: Allergy. 77 , p. 3398-3407 10 p.

Quantification of T-cell dynamics during latent cytomegalovirus infection in humans

van den Berg Sara P.H., Derksen Lyanne Y., Drylewicz Julia, Nanlohy Nening M., Beckers Lisa, Lanfermeijer Josien, Gessel Stephanie N., Vos Martijn, Otto Sigrid A., de Boer Rob J., Tesselaar Kiki, Borghans José A.M., van Baarle Debbie Dec 2021, In: PLoS Pathogens. 17

All research output

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