prof. dr. A.C.G. (Toine) Egberts

prof. dr. A.C.G. (Toine) Egberts

Full Professor
prof. dr. A.C.G. (Toine) Egberts
  • Clinical Pharmacy



Toine Egberts (1965) obtained his PharmD in 1990 at the University of Groningen, the Netherlands. Thereafter he was trained as a clinical pharmacist during four years in the hospitals of Tilburg and Delft. In 1994, he started his PhD project at the department of Pharmacoepidemiology & Clinical Pharmacology of Utrecht University in collaboration with the Netherlands Pharmacovigilance Foundation 'Lareb'. This resulted in 1997 in a thesis entitled 'Pharmacoepidemiologic approaches to the evaluation of antidepressant drugs'. During his PhD-project he obtained the Master of Science degree in clinical epidemiology at the Netherlands Institute of Health Sciences.

He was appointed in 2001 as professor of clinical pharmacoepidemiology at the department of Pharmacoepidemiology & Clinical Pharmacology. Since 2006 he is also a professor of clinical pharmacy at the medical faculty of Utrecht University. In these positions he tries to bridge the drug environment and the patient environment.

From 2006 - 2017 he was the chief pharmacist of the department of clinical pharmacy of the University Medical Center Utrecht.

Since november 2018 he is director of doctor education of the Graduate School of Life Sciences of the Utrecht University. The coaching of PhD students gives him energy as it nicely balances performing research into medical/pharmaceutical puzzles with the personal development of young academic professionals. He had the opportunity to guide over 60 PhD students towards the 'hora est'. He has always been deeply involved in education, especially the training of hospital pharmacists, for which he received in 2016 the 'Senior Jan Glerum Award'.

He is (co)author of over 450 international peer reviewed scientific publications and a reviewer for several scientific journals and international research funding organisations.

He is a member of the editorial board of the journal Drug Safety. He is member of several committees such as the CCMO, the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR), the scientific advisory board of the Mental Health Center of the University of Wurzburg.

His research activities focus on a) the clinical pharmacology / clinical pharmacoepidemiology of drugs used in the treatment of psychiatric and neurologic disorders, and b) on innovations in clinical pharmacy systems.

He is married to Karin, has two daughters (Bibi and Louisa) and one son (Kilian) and in his spare time he likes to (trail)run, bootcamp, climb mountains and to play / listen to music.

Side Activities

All mentioned activities are current:

  • professor of clinical pharmacy, department of pharmaceutical sciences Utrecht University
  • director of doctoral education Graduate School of Life Sciences Utrecht University
  • member CCMO
  • advisor clinical pharmacology group Jeroen Bossch Ziekenhuizen
  • member of the working group for a clinical guideline on deprescribing Quality Insitute Federation Medical Specialists
  • reviewer of project proposals for funding organizsations such as ZonMw
  • member of the editorial board of the journal Drug Safety
  • reviewer for several biomedical journals
  • board member of the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR)
  • chiar of the stichting KNMP fondsen
  • member scientific advisory board Zentrum fur Psychische Gesundheit, Uniklinikum Wurzburg, Germany

Fellowship and Awards

Huizinga Penning (2004)

Senior Jan Glerum prijs (2016)

Research Output (515)

Exploring a Safety Signal of Antipsychotic-Associated Pneumonia:A Pharmacovigilance-Pharmacodynamic Study

Cepaityte Dainora, Siafis Spyridon, Egberts Toine, Leucht Stefan, Kouvelas Dimitrios, Papazisis Georgios 29 apr 2021, In: Schizophrenia bulletin. 47 , p. 672-681 10 p.

CDSS-Assisted Pharmacy Intervention Reduces Feeding Tube-Related Medication Errors in Hospitalized Patients: A Focus on Medication Suitable for Feeding-Tube Administration:A Focus on Medication Suitable for Feeding-Tube Administration

Wasylewicz Arthur T M, van Grinsven Renske J B, Bikker Jessica M W, Korsten Hendrikus H M, Egberts Toine C G, Kerskes Catharina H M, Grouls Rene J E mrt 2021, In: Journal of Parenteral and Enteral Nutrition. 45 , p. 625-632 8 p.

Nature and frequency of prescription modifications in community pharmacies:A nationwide study in the Netherlands

van Loon W E Ellen, Borgsteede S D Sander, Baas G W Gert, Kruijtbosch M Martine, Buurma H Henk, De Smet P A G M Peter, Egberts A C G Toine, Bouvy M Marcel, Floor-Schreudering A Annemieke mrt 2021, In: British Journal of Clinical Pharmacology. 87 , p. 1455-1465 11 p.

Type and Extent of Information on (Potentially Critical) Quality Attributes Described in European Public Assessment Reports for Adalimumab Biosimilars

Alsamil Ali M, Giezen Thijs J, Egberts Toine C, Leufkens Hubert G, Gardarsdottir Helga mrt 2021, In: Pharmaceuticals. 14 14 p.

Monitoring of Adverse Drug Reaction-Related Parameters in Children and Adolescents Treated With Antipsychotic Drugs in Psychiatric Outpatient Clinics

Minjon Lenneke, Brozina Ivona, Egberts Toine C G, Heerdink Eibert R, van den Ban Els 25 feb 2021, In: Frontiers in Psychiatry. 12 11 p.

Comparison of consistency and complementarity of reporting biosimilar quality attributes between regulatory and scientific communities:An adalimumab case study

Alsamil Ali M, Giezen Thijs J, Egberts Toine C, Leufkens Hubert G, Gardarsdottir Helga jan 2021, In: Biologicals. 69 , p. 30-37 8 p.

Regulatory Safety Learning Driven by the Mechanism of Action: The Case of TNF-alpha Inhibitors:The Case of TNF-α Inhibitors

Minnema Lotte A., Giezen Thijs J., Hoekman Jarno, Egberts Toine C.G., Leufkens Hubert G.M., Gardarsdottir Helga 28 dec 2020, In: Clinical Pharmacology and Therapeutics. 110 , p. 123-131 9 p.

Reporting of quality attributes in scientific publications presenting biosimilarity assessments of (intended) biosimilars:a systematic literature review

Alsamil Ali M, Giezen Thijs J, Egberts Toine C, Leufkens Hubert G, Vulto Arnold G, van der Plas Martijn R, Gardarsdottir Helga 1 nov 2020, In: European Journal of Pharmaceutical Sciences. 154


Bekker C L, van den Bemt B J F, Gardarsdottir H, Egberts A C G, Bouvy M L 22 okt 2020, In: Nederlands Tijdschrift voor Geneeskunde. 164 , p. D4812

Psychotropic medication use in former ICU patients with mental health problems:A prospective observational follow-up study

Janssen Debbie G A, Jonker Joep, van Dijk Diederik, Heerdink Eibert R, Egberts Toine C G, Slooter Arjen J C okt 2020, In: Journal of Critical Care. 59 , p. 112-117 6 p.

All research output

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