dr. L.G. (Lieza) Exalto

dr. L.G. (Lieza) Exalto

Assistant Professor - medical
  • Neurologen



Lieza Exalto, is a neurologist who has received her medical training in the UMC Utrecht. In 2014 she obtained her PhD degree with the thesis “Diabetes and Dementia, the bitter taste of a sweet disease”. Afterwards she continued her research in the Vascular Cognitive Impairment group of prof. Biessels and introduced sex and gender differences as relevant research topic. Lieza received funding from Alzheimer Nederland for her project “Does sex modulate the phenotype and prognosis of vascular cognitive impairment”.


Lieza is work-package leader “sex differences” in the Dutch Heart-Brain Consortium study. She collaborates with the META-VCI MAP consortium on research projects on sex differences in post-stroke cognitive impairment. In the European multicenter H2020 study RECOGNISED, she is work-package leader of the cognitive testing. In February 2020 she received the prize for best integration of sex and gender considerations in cardiovascular research plans, during the Libin International Trainee Symposium: Research is Better with Sex and Gender! 

Research Output (36)

Sex Differences in Poststroke Cognitive Impairment:A Multicenter Study in 2343 Patients With Acute Ischemic Stroke

Exalto Lieza G, Weaver Nick A, Kuijf Hugo J, Aben Hugo P, Bae Hee-Joon, Best Jonathan G, Bordet Régis, Chen Christopher P L H, van der Giessen Ruben S, Godefroy Olivier, Gyanwali Bibek, Hamilton Olivia K L, Hilal Saima, Huenges Wajer Irene M C, Kim Jonguk, Kappelle L Jaap, Kim Beom Joon, Köhler Sebastian, de Kort Paul L M, Koudstaal Peter J, Lim Jae-Sung, Makin Stephen D J, Mok Vincent C T, van Oostenbrugge Robert J, Roussel Martine, Staals Julie, Valdés-Hernández Maria Del C, Venketasubramanian Narayanaswamy, Verhey Frans R J, Wardlaw Joanna M, Werring David J, Xu Xin, van Zandvoort Martine J E, Biesbroek J Matthijs, Chappell Francesca M, Biessels Geert Jan 8 Aug 2023, In: Stroke. 54 , p. 2296-2303 8 p.

Rhabdomyolysis, encephalopathy, epilepsy and cardiac arrhythmia

Toeback Jonas, De Pagter Mirjam, Exalto Lieza, Koop K, Van Der Heijden Joris 1 Aug 2023, In: Practical Neurology. 23 , p. 356-359 4 p.

Sexual dimorphism in peripheral blood cell characteristics linked to recanalization success of endovascular thrombectomy in acute ischemic stroke

Overmars L Malin, van Solinge Wouter W, Ruijter Hester M den, van der Worp H Bart, Van Es Bram, Hulsbergen-Veelken Cornelia A R, Biessels Geert Jan, Exalto Lieza G, Haitjema Saskia 2023, In: Journal of thrombosis and thrombolysis. 56 , p. 614-625 12 p.

Strategic white matter hyperintensity locations for cognitive impairment:A multicenter lesion-symptom mapping study in 3525 memory clinic patients

Coenen Mirthe, Kuijf Hugo J, Huenges Wajer Irene M C, Duering Marco, Wolters Frank J, Fletcher Evan F, Maillard Pauline M, Barkhof Frederik, Barnes Josephine, Benke Thomas, Boomsma Jooske M F, Chen Christopher P L H, Dal-Bianco Peter, Dewenter Anna, Enzinger Christian, Ewers Michael, Exalto Lieza G, Franzmeier Nicolai, Groeneveld Onno, Hilal Saima, Hofer Edith, Koek Dineke L, Maier Andrea B, McCreary Cheryl R, Padilla Catarina S, Papma Janne M, Paterson Ross W, Pijnenburg Yolande A L, Rubinski Anna, Schmidt Reinhold, Schott Jonathan M, Slattery Catherine F, Smith Eric E, Steketee Rebecca M E, Sudre Carole H, van den Berg Esther, van der Flier Wiesje M, Venketasubramanian Narayanaswamy, Vernooij Meike W, Xin Xu, DeCarli Charles, Biessels Geert Jan, Biesbroek J Matthijs, 12 Dec 2022, In: Alzheimer's & Dementia. 19 , p. 2420-2432 13 p.

Multimodal tract-based MRI metrics outperform whole brain markers in determining cognitive impact of small vessel disease-related brain injury

De Luca Alberto, Kuijf Hugo, Exalto Lieza, Thiebaut de Schotten Michel, Biessels Geert-Jan, , Koek Dineke Sep 2022, In: Brain structure & function. 227 , p. 2553-2567 15 p.

Neuropsychiatric Symptoms as Predictor of Poor Clinical Outcome in Patients With Vascular Cognitive Impairment

Sep Yoni C P, Leeuwis Anna E, Exalto Lieza G, Boomsma Jooske M, Prins Niels D, Verwer Jurre H, Scheltens Philip, van der Flier Wiesje M, Biessels Geert Jan, 2 Jan 2022, In: The American Journal of Geriatric Psychiatry. 30 , p. 813-824 12 p.

Neuropsychiatric symptoms in patients with possible vascular cognitive impairment, does sex matter?

Exalto L G, Boomsma J M, Sep Ycp, Leeuwis A E, Scheltens P, Biessels G J, van der Flier W M, 2022, In: Cerebral Circulation - Cognition and Behavior. 3

Vascular Cognitive Impairment and cognitive decline; a longitudinal study comparing different types of vascular brain injury - The TRACE-VCI study

Boomsma Jooske Mf, Exalto Lieza G, Barkhof Frederik, Leeuwis Anna E, Prins Niels D, Scheltens Philip, Teunissen Charlotte E, Weinstein Henry C, Biessels Geert Jan, van der Flier Wiesje M, On-Behalf-Of-The-Trace-Vci-Study-Group 2022, In: Cerebral Circulation - Cognition and Behavior. 3

Females with type 2 diabetes are at higher risk for accelerated cognitive decline than males:CAROLINA-COGNITION study

Verhagen Chloë, Janssen Jolien, Biessels Geert Jan, Johansen Odd Erik, Exalto Lieza G 27 Oct 2021, In: NMCD : Nutrition metabolism and cardiovascular diseases. 32 , p. 355-364 10 p.

Sex and Cardiovascular Function in Relation to Vascular Brain Injury in Patients with Cognitive Complaints

Kuipers Sanne, Biessels Geert Jan, Greving Jacoba P, Amier Raquel P, de Bresser Jeroen, Bron Esther E, van der Flier Wiesje M, van der Geest Rob J, Hooghiemstra Astrid M, van Oostenbrugge Robert J, van Osch Matthias J P, Kappelle L Jaap, Exalto Lieza G, 26 Oct 2021, In: Journal of Alzheimer's Disease. 84 , p. 261-271 11 p.

All research output

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