dr. K. (Kathelijn) Fischer

dr. K. (Kathelijn) Fischer

Associate Professor - medical
dr. K. (Kathelijn) Fischer
  • Hematology/Van Creveldclinic

Research Programs



Kathelijn Fischer has been working at the University Medical Center Utrecht, both as a Paediatric Haematologist and a Clinical Epidemiologist.

Dr Fischer finished her medical training in 1988 is a registered paediatrician since 1994. Dr Fischer specialized in paediatric haematology and oncology in Utrecht, the Netherlands. Subsequently, she performed PhD research in haemophilia while training as a clinical epidemiologist. She published her thesis on ‘Treatment strategies in severe haemophilia: in search for the optimal treatment’ in 2001.

Dr Fischer supervises four PhD students and served as co-promotor for seven other PhD students in the field of haematology, neurology and gynaecology.

Dr Fischer is principal investigator in several international studies on long-term results of haemophilia treatment, and is the epidemiologist for the European Haemophilia Safety Surveillance Study (EUHASS-member of the steering committee) as well as for the European PedNet registry.

The specific areas of expertise and interest of dr Fischer include the epidemiology of haemophilia (including use of registries), prophylactic treatment, and outcome assessment in haemophilia care.

Side Activities

  • Membership of international working groups: International Prophylaxis Study Group (IPSG), European Association for Haemophilia and Allied Disorders (EAHAD; former EC member), she is a former co-chair of the FVIII/IX SSC subcommittee of the ISTH and participated in the group that drafted the Principles of Haemophilia Care.
  • Member of the National Haemophilia Registry Committee of the Dutch Haemophilia Treaters Board (NVHB)
  • Membership professional organisations: NVK (Dutch Paediatric Society,- section benign haematology), ISTH (International Society for Thrombosis and Haemostasis), WFH (World Federation for Haemophilia)
  • Section editor for Thrombosis and Haemostasis journal, member of the editorial board for Haemophilia journal

Fellowship and Awards

Bayer Haemophilia Special Project Award (2005)

Research Output (322)

DosEmi study protocol:a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia A

Donners Anouk, van der Zwet Konrad, Egberts Antoine C G, Fijnvandraat Karin, Mathôt Ron, Kruis Ilmar, Cnossen Marjon H, Schutgens Roger, Urbanus Rolf T, Fischer Kathelijn 26 Jun 2023, In: BMJ Open. 13

Insights in the Prothrombotic Changes after Implantation of a Left Ventricular Assist Device in Patients with End-Stage Heart Failure:A Longitudinal Observational Study

Liesdek Omayra C.D., Urbanus Rolf T., De Maat Steven, De Heer Linda M., Ramjankhan Faiz Z., Sebastian Silvie A.E., Huisman Albert, De Jonge Nicolaas, Vink Aryan, Fischer Kathelijn, Maas Coen, Suyker Willem J.L., Schutgens Roger E.G. 1 May 2023, In: ASAIO journal. 69 , p. 438-444 7 p.

Screening for subclinical synovial proliferation in haemophilia:A systematic review and meta-analysis comparing physical examination and ultrasound

van Leeuwen Flora H.P., Timmer Merel A., de Jong Pim A., Fischer Kathelijn, Foppen Wouter Mar 2023, In: Haemophilia. 29 , p. 445-455 11 p.

No immunological changes after factor VIII product switch:An in depth analysis in haemophilia A patients

Schep Sarah J, Fischer Kathelijn, Boes Marianne, Schutgens Roger E G 2023, In: Haemophilia. 29 , p. 1039-1048 10 p.

Low dose emicizumab prophylaxis in haemophilia a patients:A pilot study from India

Bansal Shweta, Donners Anouk A.M.T., Fischer Kathelijn, Kshirsagar Shrinath, Rangarajan Savita, Phadke Varsha, Mhatre Shrutika, Sontate Bharati, silva Magdelene D’, Ansari Shahana, Shetty Shrimati 2023, In: Haemophilia. 29 , p. 931-934 4 p.

Long-term joint outcomes in adolescents with moderate or severe haemophilia A

Schmidt David E, Michalopoulou Aikaterini, Fischer Kathelijn, Motwani Jayashree, Andersson Nadine G, Pergantou Helen, Ranta Susanna, 4 Aug 2022, In: Haemophilia. 28 , p. 1054-1061 8 p.

Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling

Janssen Alexander, Hoogendoorn Mark, Cnossen Marjon H., Mathôt Ron A.A., Cnossen M. H., Reitsma S. H., Leebeek F. W.G., Mathôt R. A.A., Fijnvandraat K., Coppens M., Meijer K., Schols S. E.M., Eikenboom H. C.J., Schutgens R. E.G., Beckers E. A.M., Ypma P., Kruip M. J.H.A., Polinder S., Tamminga R. Y.J., Brons P., Fischer K., van Galen K. P.M., Heubel-Moenen F. C.J.I., Nieuwenhuizen L., Driessens M. H.E., van Vliet I., Lock J., Hazendonk H. C.A.M., van Moort I., Heijdra J. M., Goedhart M. H.J., Al Arashi W., Preijers T., de Jager N. C.B., Bukkems L. H., Cloesmeijer M. E., Janssen A., Collins P. W., Liesner R., Chowdary P., Millar C. M., Hart D., Keeling D., Aug 2022, In: CPT: Pharmacometrics and Systems Pharmacology. 11 , p. 1100-1110 11 p.

Desmopressin testing in von Willebrand disease:Lowering the burden

Heijdra Jessica M., Atiq Ferdows, Al Arashi Wala, Kieboom Quincy, Wuijster Esmee, Meijer Karina, Kruip Marieke J.H.A., Leebeek Frank W.G., Cnossen Marjon H., , Fijnvandraat K., Mathôt R. A.A., Polinder S., Coppens M., Tamminga R. Y.J., Meijer K., Laros-van Gorkom B. A.P., Brons P., Schols S. E.M., van der Meer F. J.M., Eikenboom H. C.J., Schutgens R. E.G., Fischer K., Heubel-Moenen F., Nieuwenhuizen L., Ypma P., Driessens M. H.E., Zwaan C. M., van Vliet I., Collins P. W., Liesner R., Chowdary P., Keeling D., Lock J., Hazendonk H. C.A.M., van Moort I., Preijers T., de Jager N. C.B., Goedhart M. C.H.J., Bukkems L. H., Cloesmeijer M. E., Janssen A. Aug 2022, In: Research and practice in thrombosis and haemostasis. 6

Validation of the pedHALshort and HALshort in Dutch children and adults with haemophilia

Kuijlaars Isolde A R, van der Net Janjaap, van Vulpen Lize F D, Driessens Mariette H E, Schols Saskia E M, Tan Melanie, Gouw Samantha C, Fischer Kathelijn 29 Jul 2022, In: Haemophilia. 28 , p. 1007-1015 9 p.

Predicting Individual Changes in Terminal Half-Life After Switching to Extended Half-Life Concentrates in Patients With Severe Hemophilia

Versloot Olav, Iserman Emma, Chelle Pierre, Germini Federico, Edginton Andrea N, Schutgens Roger E G, Iorio Alfonso, Fischer Kathelijn 21 Apr 2022, In: HemaSphere. 6 , p. 1-7

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht





Practical maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet