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dr. M. (Magdaléna) Harakalová

dr. M. (Magdaléna) Harakalová

Assistant Professor

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Research Output (73)

Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

Maas Renee G.C., Lee Soah, Harakalova Magdalena, Snijders Blok Christian J.B., Goodyer William R., Hjortnaes Jesper, Doevendans Pieter A.F.M., Van Laake Linda W., van der Velden Jolanda, Asselbergs Folkert W., Wu Joseph C., Sluijter Joost P.G., Wu Sean M., Buikema Jan W. 19 Mar 2021, In: STAR protocols. 2

P62-positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy

van der Klooster Zoë Joy, Sepehrkhouy Shahrzad, Dooijes Dennis, Te Rijdt Wouter P, Schuiringa Frederique S A M, Lingeman Jolanthe, van Tintelen Johannes Peter, Harakalova Magdalena, Goldschmeding Roel, Suurmeijer Albert J H, Asselbergs Folkert W, Vink Aryan 18 Feb 2021, In: Journal of Cellular and Molecular Medicine. 25 , p. 3160-3166 7 p.

Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy

Feyen Dries A.M., Perea-Gil Isaac, Maas Renee G.C., Harakalova Magdalena, Gavidia Alexandra A., Arthur Ataam Jennifer, Wu Ting Hsuan, Vink Aryan, Pei Jiayi, Vadgama Nirmal, Suurmeijer Albert J., Te Rijdt Wouter P., Vu Michelle, Amatya Prashila L., Prado Maricela, Zhang Yuan, Dunkenberger Logan, Sluijter Joost P.G., Sallam Karim, Asselbergs Folkert W., Mercola Mark, Karakikes Ioannis 2021, In: Circulation. 144 , p. 382-392 11 p.

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

Schuldt Maike, Pei Jiayi, Harakalova Magdalena, Dorsch Larissa M, Schlossarek Saskia, Mokry Michal, Knol Jaco C, Pham Thang V, Schelfhorst Tim, Piersma Sander R, Dos Remedios Cris, Dalinghaus Michiel, Michels Michelle, Asselbergs Folkert W, Moutin Marie-Jo, Carrier Lucie, Jimenez Connie R, van der Velden Jolanda, Kuster Diederik W D 2021, In: Circulation. Heart Failure. 14 , p. 39-55

Strength of patient cohorts and biobanks for cardiomyopathy research

de Boer R. A., Nijenkamp L. L.A.M., Silljé H. H.W., Eijgenraam T. R., Parbhudayal R., van Driel B., Huurman R., Michels M., Pei J., Harakalova M., van Lint F. H.M., Jansen M., Baas A. F., Asselbergs F. W., van Tintelen J. P., Brundel B. J.J.M., Dorsch L. M., Schuldt M., Kuster D. W.D., van der Velden J., 1 Aug 2020, In: Netherlands Heart Journal. 28 , p. 50-56 7 p.

Gene expression profiling of hypertrophic cardiomyocytes identifies new players in pathological remodelling

Vigil-Garcia Marta, Demkes Charlotte J, Eding Joep E C, Versteeg Danielle, de Ruiter Hesther, Perini Ilaria, Kooijman Lieneke, Gladka Monika M, Asselbergs Folkert W, Vink Aryan, Harakalova Magdalena, Bossu Alexander, van Veen Toon A B, Boogerd Cornelis J, van Rooij Eva 27 Jul 2020, In: Cardiovascular research. 117 , p. 1532-1545 14 p.

H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

Pei Jiayi, Harakalova Magdalena, Treibel Thomas A, Lumbers R Thomas, Boukens Bastiaan J, Efimov Igor R, van Dinter Jip T, González Arantxa, López Begoña, El Azzouzi Hamid, van den Dungen Noortje, van Dijk Christian G M, Krebber Merle M, den Ruijter Hester M, Pasterkamp Gerard, Duncker Dirk J, Nieuwenhuis Edward E S, de Weger Roel, Huibers Manon M, Vink Aryan, Moore Jason H, Moon James C, Verhaar Marianne C, Kararigas Georgios, Mokry Michal, Asselbergs Folkert W, Cheng Caroline 14 Jul 2020, In: Clinical Epigenetics. 12 18 p.

Integration of high-dimensional omics data using sparse orthogonal 2-way partial least squares

Gu Zhujie, el Bouhaddani Said, Harakalova Magdalena, Houwing-Duistermaat Jeanine J., Uh Hae-Won Jul 2020, In: Genetic Epidemiology. 44 , p. 522-522

UNRAVEL:big data analytics research data platform to improve care of patients with cardiomyopathies using routine electronic health records and standardised biobanking

Sammani A., Jansen M., Linschoten M., Bagheri A., de Jonge N., Kirkels H., van Laake L. W., Vink A., van Tintelen J. P., Dooijes D., te Riele A. S.J.M., Harakalova M., Baas A. F., Asselbergs F. W. 1 Sep 2019, In: Netherlands Heart Journal. 27 , p. 426-434 9 p.

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