dr. P. (Pauline) Heus

dr. P. (Pauline) Heus

Assistant Professor
dr. P. (Pauline) Heus
  • Julius Center, dept. Epidemiology & Health Economics



Pauline Heus graduated as optometrist and orthoptist from the Hogeschool Utrecht in 2001. Until 2014 she worked at the ophthalmology department of Northwest Clinics in Alkmaar. Between 2006 and 2014 she actively contributed to the profession of optometry in the Netherlands as a board member of the Dutch Optometric Association (Optometristen Vereniging Nederland, OVN).

After obtaining a master’s degree in Evidence Based Practice (with distinction) at the University of Amsterdam, Pauline joined Cochrane Netherlands in 2011 (hosted by the Julius Center since 2014). Besides contributing to evidence syntheses and providing methodological support to authors of (Cochrane) systematic reviews, she is also involved in teaching. Her main research area of interest is the translation of evidence into clinical practice. In 2020, Pauline obtained her PhD degree at Utrecht University on a thesis titled "Maximizing research value: adequate reporting and effective (de-)implementation strategies". One of her research topics is the reporting of prediction model studies. Furthermore, she is involved in a program of the Netherlands Federation of University Medical Centers (NFU) about de-implementation of low-value care, called  ‘To do or not to do?’. 

Pauline is member of the Cochrane Bias Methods Group, Cochrane Knowledge Translation Working Group 'Growing Capacity in Users', and the international GRADE Working Group.


Research Output (45)

Indicators of questionable research practices were identified in 163,129 randomized controlled trials

Damen Johanna A, Heus Pauline, Lamberink Herm J, Tijdink Joeri K, Bouter Lex, Glasziou Paul, Moher David, Otte Willem M, Vinkers Christiaan H, Hooft Lotty 2 Dec 2022, In: Journal of Clinical Epidemiology. 154 , p. 23-32 10 p.

Transparante wetenschappelijke onderbouwing van zorg

Langendam Miranda W., Kuijpers Ton, Heus Pauline, Verstijnen Ilse, Vernooij Robin, Boluyt Nicole, Hooft Lotty 17 Oct 2022, In: Nederlands Tijdschrift voor Geneeskunde. 166

Reducing low-value care:what can we learn from eight de-implementation studies in the Netherlands?

Verkerk Eva W., Van Dulmen Simone A., Westert Gert P., Hooft Lotty, Heus Pauline, Kool Rudolf B. 7 Sep 2022, In: BMJ Open Quality. 11

The score after 10 years of registration of systematic review protocols

van der Braak Kim, Ghannad Mona, Orelio Claudia, Heus Pauline, Damen Johanna A.A., Spijker René, Robinson Karen, Lund Hans, Hooft Lotty 5 Sep 2022, In: Systematic Reviews. 11 , p. 1-10

Strategieën om niet-gepaste diagnostiek terug te dringen

Heus Pauline, van Doorn Sander, Takada Toshihiko, Naaktgeboren Christiana, Weenink Jan Willem, van Dulmen Simone, Hooft L. Aug 2022, In: Huisarts en Wetenschap. 65 , p. 10-14 5 p.

What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration:a systematic review

Pameijer Els M, Heus Pauline, Damen Johanna A A, Spijker René, Hooft Lotty, Ringens Peter J, Imhof Saskia M, van Leeuwen Redmer 13 Jun 2022, In: Acta Ophthalmologica. 100 , p. e1541-e1552

The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement

Vinkers Christiaan H, Lamberink Herm J, Tijdink Joeri K, Heus Pauline, Bouter Lex, Glasziou Paul, Moher David, Damen Johanna A, Hooft Lotty, Otte Willem M 19 Apr 2021, In: PLoS Biology. 19 , p. 1-16

Reducing Inappropriate Proton Pump Inhibitors Use for Stress Ulcer Prophylaxis in Hospitalized Patients:Systematic Review of De-Implementation Studies

Orelio Claudia C, Heus Pauline, Kroese-van Dieren Judith J, Spijker René, van Munster Barbara C, Hooft Lotty 2021, In: Journal of General Internal Medicine. 36 , p. 2065-2073 9 p.

Clinical utility of limited channel sleep studies versus polysomnography for obstructive sleep apnoea

van Doorn Sander, Heus Pauline, Damen Johanna A.A.G., Spijker Rene, Japenga Eva J., Reesink Herre, Scholten Rob J.P.M., Hooft Lotty 15 Dec 2020, In: Cochrane Database of Systematic Reviews. 2020 , p. 1-8

Strategies to reduce the use of low-value medical tests in primary care: a systematic review

Takada Toshihiko, Heus Pauline, van Doorn Sander, Naaktgeboren Christiana A., Weenink Jan-Willem, van Dulmen Simone A., Hooft Lotty 1 Dec 2020, In: British Journal of General Practice. 70 , p. E858-E865

All research output

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