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dr. J.W.M. (Jo ) Hoppener

Associate Professor

  • Group Burgering, section Molecular Cancer Research

Research Output (71)

Ethics: Genetic testing for MEN1-whose responsibility?

Lips C.J.M., Höppener J.W.M. 2012, In: Nature Reviews. Endocrinology. 8 , p. 575-576 2 p.

Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation.

Lips C.J.M., Dreijerink K.M.A., Hoppener J.W.M. 2012, In: Clinics (São Paulo, Brazil). 67 , p. 49-56 8 p.

The role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes

Khemtemourian L.P., Engel M.F.M., Kruijtzer J.A.W., Hoppener J.W.M., Liskamp R.M.J., Killian J.A. 2010, In: European Biophysics Journal. 39 , p. 1359-1364 6 p.

The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition

Khemtemourian L.P., Engel M.F.M., Liskamp R.M.J., Höppener J.W.M., Killian J.A. 2010, In: Biochimica et Biophysica Acta-Biomembranes. 1798 , p. 1805-1811 7 p.

A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity

Timmerman P., Barderas R., Desmet J., Altschuh D., Shochat S., Hollestelle M.J., Hoppener J.W.M., Monasterio A., Casal J.I., Meloen R.H. 2009, In: Journal of Biological Chemistry. 284 , p. 34126-34134 9 p.

The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation.

Dreijerink K.M.A., Varier R.A., van Beekum O., Jeninga E.H., Hoppener J.W.M., Lips C.J.M., Kummer J.A., Kalkhoven E., Timmers H.T.M. 2009, In: Molecular and Cellular Biology. 29 , p. 5060-5069 10 p.

Medullary thyroid carcinoma and biomarkers: past, present and future

van Veelen W., de Groot J.W.B., Acton D.S., Hofstra R.M., Hoppener J.W.M., Links T.P., Lips C.J.M. 2009, In: Journal of Internal Medicine. 266 , p. 126-140 15 p.

P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development.

van Veelen W., Klompmaker R., Gloerich M., van Gasteren C.J.R., Kalkhoven E., Berger R., Lips C.J.M., Medema R.H., Höppener J.W.M., Acton D.S. 2009, In: International Journal of Cancer. 124 , p. 339-345 6 p.

Tissue selectivity in multiple endocrine neoplasia type 1-associated tumorigenesis

Gracanin A., Dreijerink K.M.A., van der Luijt R.B., Lips C.J.M., Hoppener J.W.M. 2009, In: Cancer Research. 69 , p. 6371-6374 4 p.

Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro

Khemtémourian L.P., Lahoz Casarramona G., Suylen D.P., Hackeng T.M., Meeldijk J.D., de Kruijff B., Hoppener J.W.M., Killian J.A. 2009, In: Biochemistry. 48 , p. 10918-10925 8 p.