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prof. dr. A.D.R. (Alwin) Huitema

prof. dr. A.D.R. (Alwin) Huitema

Full Professor
prof. dr. A.D.R. (Alwin) Huitema
  • Clinical Pharmacy

Research Programs

Strategic Program Cancer

Side Activities

2002 - 2021 : Member of the Medical Ethical Committee of Netherlands Cancer Institute

2003 - : Involved in many early clinical trials of novel anticancer agents (not further specified, revenues for Netherlands Cancer Institute)

2016 - 2018: Member of scientific councel "Stichting Kinderen Kankervrij (KiKa)"

2017 - 2021 : Member of the working group Oncology & Hematology of "Horizonscan geneesmiddelen", ZorgInstituut Nederland

2018 - : Board member of Dutch Society of Clinical Pharmacology & Biopharmaceutics

2021 - : Member of the external evaluation committee of 10 year program "Goed Geneesmiddelen Gebruik"

Fellowship and Awards

2015 Galenus research prize

2014 Huizinga penning of the Dutch Association of Hospital Pharmacists

Research Output (222)

Precision Dosing of Targeted Therapies Is Ready for Prime Time

Groenland Stefanie L, Verheijen Remy B, Joerger Markus, Mathijssen Ron H J, Sparreboom Alex, Beijnen Jos H, Beumer Jan H, Steeghs Neeltje, Huitema Alwin D R 15 dec 2021, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 27 , p. 6644-6652 9 p.

Aminoglycoside- and glycopeptide-induced ototoxicity in children:a systematic review

Diepstraten F A, Hoetink A E, van Grotel M, Huitema A D R, Stokroos R J, van den Heuvel-Eibrink M M, Meijer A J M dec 2021, In: JAC-antimicrobial resistance. 3 , p. 1-10

Intra-tumoral pharmacokinetics of pazopanib in combination with radiotherapy in patients with non-metastatic soft-tissue sarcoma

Molenaar-Kuijsten Laura, van Meekeren Milan, Verheijen Remy B., Bovée Judith V.M.G., Fiocco Marta, Thijssen Bas, Rosing Hilde, Huitema Alwin D.R., Miah Aisha B., Gelderblom Hans, Haas Rick L.M., Steeghs Neeltje 18 nov 2021, In: Cancers. 13 , p. 1-12

Response to “Optimized Alectinib Dose Regimen for Treatment of Patients With ALK-Positive NSCLC Based on Robust Pharmacometric Analyses and Clinical Evidence”

Groenland Stefanie L., Geel Dieuwertje R., Beijnen Jos H., Smit Egbert F., Huitema Alwin D.R., Steeghs Neeltje nov 2021, In: Clinical Pharmacology and Therapeutics. 110 , p. 1164-1164 1 p.

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women

Joosten Stacey E.P., Wellenstein Marius, Koornstra Rutger, van Rossum Annelot, Sanders Joyce, van der Noort Vincent, Ferrandez Maria C., Harkes Rolf, Mandjes Ingrid A.M., Rosing Hilde, Huitema Alwin, Beijnen Jos H., Wesseling Jelle, van Diest Paul J., Horlings Hugo M., Linn Sabine C., Zwart Wilbert 20 okt 2021, In: npj Breast Cancer. 7 , p. 1-8

Toxicity of pemetrexed during renal impairment explained—Implications for safe treatment

Boosman René J., Dorlo Thomas P.C., de Rouw Nikki, Burgers Jacobus A., Dingemans Anne Marie C., van den Heuvel Michel M., Hendriks Lizza E.L., Biesma Bonne, Aerts Joachim G.J.V., Croes Sander, Mathijssen Ron H.J., Huitema Alwin D.R., ter Heine Rob 15 okt 2021, In: International Journal of Cancer. 149 , p. 1576-1584 9 p.

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry

Amrani Mohsin El, Gerencser Laszlo, Huitema Alwin D R, Hack C Erik, van Luin Matthijs, van der Elst Kim C M 11 okt 2021, In: Journal of Chromatography A. 1655 , p. 1-10

Quality Control of Busulfan Plasma Quantitation, Modeling, and Dosing:An Interlaboratory Proficiency Testing Program

McCune Jeannine S., Punt Arjen M., Yeh Rosa F., Dupuis L. Lee, Kweekel Dina M., Franssen Eric J.F., Ritchie James C., van Maarseveen Erik, Huitema Alwin D.R. 1 okt 2021, In: Therapeutic drug monitoring. 43 , p. 657-663 7 p.

A Review of CYP3A Drug-Drug Interaction Studies:Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs

Molenaar-Kuijsten Laura, Van Balen Dorieke E.M., Beijnen Jos H., Steeghs Neeltje, Huitema Alwin D.R. 30 aug 2021, In: Frontiers in Pharmacology. 12 , p. 1-20

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of Ga-68-DOTATATE in patients without neuroendocrine tumors

Siebinga H., de Wit-van der Veen B. J., Beijnen J. H., Stokkel M. P.M., Dorlo T. P.C., Huitema A. D.R., Hendrikx J. J.M.A. 16 aug 2021, In: EJNMMI Research. 11 , p. 1-12

All research output

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