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prof. dr. A.D.R. (Alwin) Huitema

prof. dr. A.D.R. (Alwin) Huitema

Full Professor

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Research Output (286)

Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma

Knörr Fabian, Schellekens Kim P.J., Schoot Reineke A., Landman-Parker Judith, Teltschik Heiko Manuel, Förster Jan, Riquelme Amambay, Huitema Alwin D.R., van Eijkelenburg Natasha K.A., Beishuizen Auke, Zwaan C. Michel, Woessmann Wilhelm, van der Lugt Jasper May 2023, In: Haematologica. 108 , p. 1442-1446 5 p.

Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model

't Hart E, Bianco J, Bruin M A C, Derieppe M, Besse H C, Berkhout K, Chin Joe Kie L A, Su Y, Hoving E W, Huitema A D R, Ries M G, van Vuurden D G 5 Apr 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 357 , p. 287-298 12 p.

Clinical development of WEE1 inhibitors in gynecological cancers:A systematic review

Schutte Tim, Embaby Alaa, Steeghs Neeltje, van der Mierden Stevie, van Driel Willemien, Rijlaarsdam Martin, Huitema Alwin, Opdam Frans Apr 2023, In: Cancer Treatment Reviews. 115 15 p.

Potential of Mesalazine Therapeutic Drug Monitoring by Measuring Fecal Excretion in Patients With Ulcerative Colitis

van de Meeberg Maartje M, Verheij Elwin R, Fidder Herma H, Bouma Gerd, Huitema Alwin D R, Oldenburg Bas 22 Feb 2023, In: Therapeutic drug monitoring. 45 , p. 668-675 8 p.

A sensitive liquid chromatographic-mass spectrometry method for the quantification of vincristine in whole blood collected with volumetric absorptive microsampling

van der Heijden Lisa T., Uittenboogaard Aniek, Nijstad A. Laura, Gebretensae Abadi, Kaspers Gertjan J.L., Beijnen Jos H., Huitema Alwin D.R., Rosing Hilde 20 Feb 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 225

A physiologically based pharmacokinetic model for [<sup>68</sup>Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients

Siebinga Hinke, de Wit-van der Veen Berlinda J., Beijnen Jos H., Dorlo Thomas P.C., Huitema Alwin D.R., Hendrikx Jeroen J.M.A. 3 Feb 2023, In: EJNMMI Research. 13 16 p.

Time above threshold plasma concentrations as pharmacokinetic parameter in the comparison of oral and intravenous docetaxel treatment of breast cancer tumors

Van Eijk Maarten, Beijnen Jos H., Huitema Alwin D.R. 1 Feb 2023, In: Anti-Cancer Drugs. 34 , p. 281-289 9 p.

Prediction of the pharmacokinetics of pemetrexed with a low test dose:A proof-of-concept study

Boosman René J., de Rouw Nikki, Huitema Alwin D.R., Burgers Jacobus A., ter Heine Rob Feb 2023, In: British Journal of Clinical Pharmacology. 89 , p. 699-704 6 p.

Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling

McCune Jeannine S., Navarro Sandi L., Baker K. Scott, Risler Linda J., Phillips Brian R., Randolph Timothy W., Shireman Laura, Schoch H. Gary, Deeg H. Joachim, Zhang Yuzheng, Men Alex, Maton Loes, Huitema Alwin D.R. Feb 2023, In: Clinical Pharmacology and Therapeutics. 113 , p. 370-379 10 p.

A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens

van der Heijden Lisa, van Nuland Merel, Beijnen Jos, Huitema Alwin, Dorlo Thomas Feb 2023, In: Clinical and Translational Science. 16 , p. 258-268 11 p.

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