dr. I. (Ivana) Isgum

Associate Professor
dr. I. (Ivana) Isgum
  • Image Sciences Institute

Research Programs



Ivana Išgum graduated in Mathematics at the University of Zagreb, Croatia in 1999. The same year she was employed as a scientific software engineer at Silicon Biomedical Instruments BV, The Netherlands. In 2001 she became a PhD student at the Image Sciences Institute. Her PhD degree was obtained in 2007 with a thesis entitled Computer-aided detection and quantification of arterial calcifications with CT. She then worked for a year as a PostDoc at the Laboratory for Clinical and Experimental Image Processing in Leiden University Medical Center on the detection of atherosclerotic carotid plaque from combined magnetic resonance angiography and vessel wall images. Ivana is currently an Associate Professor at UMC Utrecht where she is leading Quantitative Medical Image Analysis (QIA) group at the Image Sciences Institute. QIA group is focusing on the development of algorithms for quantitative analysis of medical images to enable automatic patient diagnosis and prognosis using techniques from the fields of machine learning and deep learning.

Research Output (164)

The prognostic value of automated coronary calcium derived by a deep learning approach on non-ECG gated CT images from 82Rb-PET/CT myocardial perfusion imaging

Dekker Mirthe, Waissi Farahnaz, Bank Ingrid E M, Isgum Ivana, Scholtens Asbjørn M, Velthuis Birgitta K, Pasterkamp Gerard, de Winter Robbert J, Mosterd Arend, Timmers Leo, de Kleijn Dominique P V 2021, In: International Journal of Cardiology. 329 , p. 9-15 7 p.

Automatic segmentation of the olfactory bulbs in MRI

Noothout Julia M.H., Postma Elbrich M., Boesveldt Sanne, De Vos Bob D., Smeets Paul A.M., Išgum Ivana 2021,

Combined analysis of coronary arteries and the left ventricular myocardium in cardiac CT angiography for detection of patients with functionally significant stenosis

Zreik Majd, Hampe Nils, Leiner Tim, Khalili Nadih, Wolterink Jelmer M., Voskuil Michiel, Viergever Max A., Išgum Ivana 2021,

Identification of Risk of Cardiovascular Disease by Automatic Quantification of Coronary Artery Calcifications on Radiotherapy Planning CT Scans in Patients with Breast Cancer

Gal Roxanne, Van Velzen Sanne G.M., Hooning Maartje J., Emaus Marleen J., Van Der Leij Femke, Gregorowitsch Madelijn L., Blezer Erwin L.A., Gernaat Sofie A.M., Lessmann Nikolas, Sattler Margriet G.A., Leiner Tim, De Jong Pim A., Teske Arco J., Verloop Janneke, Penninkhof Joan J., Vaartjes Ilonca, Meijer Hanneke, Van Tol-Geerdink Julia J., Pignol Jean Philippe, Van Den Bongard Desirée H.J.G., Išgum Ivana, Verkooijen Helena M. 2021, In: JAMA Oncology. 7 , p. 1024-1032 9 p.

Automatic segmentation with detection of local segmentation failures in cardiac MRI

Sander Jörg, de Vos Bob D, Išgum Ivana 10 dec 2020, In: Scientific Reports. 10

The risk of cardiovascular disease in irradiated breast cancer patients:The role of cardiac calcifications and adjuvant treatment

Gal R., van Velzen S. G., Emaus M. J., van den Bongard D. H., Gregorowitsch M. L., Blezer E. L., Sofie G., Lessmann N., Sattler M. G., Hooning M. J., Teske A. J., Penninkhof J. J., Meijer H., Pignol J. P., Verloop J., Išgum I., Verkooijen H. M., okt 2020, In: European Journal of Cancer. 138 , p. S6

Deep learning from dual-energy information for whole-heart segmentation in dual-energy and single-energy non-contrast-enhanced cardiac CT

Bruns Steffen, Wolterink Jelmer M, Takx Richard A P, van Hamersvelt Robbert W, Suchá Dominika, Viergever Max A, Leiner Tim, Išgum Ivana 12 aug 2020, In: Medical Physics. 47 , p. 5048-5060 13 p.

Deep Learning-Based Regression and Classification for Automatic Landmark Localization in Medical Images

Noothout Julia M H, De Vos Bob D, Wolterink Jelmer M, Postma Elbrich M, Smeets Paul A M, Takx Richard A P, Leiner Tim, Viergever Max A, Isgum Ivana 13 jul 2020, In: IEEE transactions on medical imaging. 39 , p. 4011-4022 12 p.

Multifocal cardiovascular calcification in patients with established cardiovascular disease; prevalence, risk factors, and relation with recurrent cardiovascular disease

van 't Klooster Cilie C., Nathoe Hendrik M., Hjortnaes J., Bots Michiel L., Isgum Ivana, Lessmann Nikolas, van der Graaf Yolanda, Leiner Tim, Visseren Frank L.J., 1 apr 2020, In: IJC Heart and Vasculature. 27

Deep learning for automatic calcium scoring in CT:Validation using multiple cardiac CT and chest CT protocols

van Velzen Sanne G.M., Lessmann Nikolas, Velthuis Birgitta K., Bank Ingrid E.M., van den Bongard Desiree H.J.G., Leiner Tim, de Jong Pim A., Veldhuis Wouter B., Correa Adolfo, Terry James G., Carr John Jeffrey, Viergever Max A., Verkooijen Helena M., Išgum Ivana apr 2020, In: Radiology. 295 , p. 66-79 14 p.

All research output

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