prof. dr. R.S. (René) Kahn

Full Professor
prof. dr. R.S. (René) Kahn
  • Psychiatry

Research Programs




Dr René Kahn is Professor and until 2017, was Chair of the Department of Psychiatry and Head of the Division of Neurosciences at the University Medical Center, Utrecht, The Netherlands. In 1995 he received a Fulbright Scholarship for study at Yale and subsequently did a Fellowship in Biological Psychiatry at the Montefiore Hospital and Albert Einstein College of Medicine in New York. He then moved to the Mount Sinai School of Medicine where he conducted schizophrenia research and became Unit Chief of one of the research units.

Dr Kahn has received many grants for his research into the origins and treatment of schizophrenia. His current research interests include neuroimaging in schizophrenia and the genetic dissection of complex traits in specific psychiatric disorders. He has published over 500 research papers and book chapters. He is on the editorial boards of Schizophrenia research, Schizophrenia Bulletin, Early Interventions in Psychiatry and European Neuropsychopharmacology. He was both Treasurer and Vice-President of the European College for Neuropsychopharmacology and currently is President-Elect of the Schizophrenia International Research Society. He sat on the Neuroscience andd Mental Health Board of the Medical Research Council of the UK and was on the scientific advisory group for CNS of the European Medicines Agency. He leads a large EU-funded study, OPTiMiSE, on developing a treatment algorithm in first episode schizophrenia. He is honorary lifetime professor at Jilin University in Changchun, P.R. China and a member of the Royal Netherlands Academy of Arts and Sciences.

As of January 2017, he is appointed head of the Department of Psychiatry at Icahn School of Medicine at Mount Sinai in New York. His main tasks at UMC Utrecht are now: coaching his PhD students and coordinating research projects.

Most recent key publications

1: Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE, EUFEST study group. E
2: van der Schot AC, Vonk R, Brans RG, van Haren NE, Koolschijn PC, Nuboer V, Schnack HG, van Baal GC, Boomsma DI, Nolen WA, Hulshoff Pol HE, Kahn RS. Influence of genes and environment on brain volumes in twin pairs concordant and discordant for bipolar disorder. Arch Gen Psychiatry. 2009 Feb,66(2):142-51
3: van der Schot AC, Vonk R, Brouwer RM, van Baal GC, Brans RG, van Haren NE, Schnack HG, Boomsma DI, Nolen WA, Pol HE, Kahn RS. Genetic and environmental influences on focal brain density in bipolar disorder. Brain. 2010 Sep 12
4: van Haren NE, Schnack HG, Cahn W, van den Heuvel MP, Lepage C, Collins L, Evans AC, Hulshoff Pol HE, Kahn RS Changes in cortical thickness during the course of illness in schizophrenia Arch Gen Psychiatry. 2011 Sep,68(9):871-80
5: van Haren NE, Rijsdijk F, Schnack HG, Picchioni MM, Toulopoulou T, Weisbrod M, Sauer ,H, van Erp TG, Cannon TD, Huttunen MO, Boomsma DI, Hulshoff Pol HE, Murray RM, Kahn RS. The genetic and environmental determinants of the association between brain abnormalities and schizophrenia: the schizophrenia twins and relatives consortium. Biol Psychiatry. 2012 May 15,71(10):915-21

Fellowship and Awards

1985 Fulbright Scholarship
1989 Ramaer Medaille
2009 Member Royal Netherlands Academy for Arts and Sciences

Research Output (1040)

Extensions of Multiple-Group Item Response Theory Alignment:Application to Psychiatric Phenotypes in an International Genomics Consortium

Mansolf Maxwell, Vreeker Annabel, Reise Steven P, Freimer Nelson B, Glahn David C, Gur Raquel E, Moore Tyler M, Pato Carlos N, Pato Michele T, Palotie Aarno, Holm Minna, Suvisaari Jaana, Partonen Timo, Kieseppä Tuula, Paunio Tiina, Boks Marco, Kahn René, Ophoff Roel A, Bearden Carrie E, Loohuis Loes Olde, Teshiba Terri, deGeorge Daniella, Bilder Robert M, okt 2020, In: Educational and Psychological Measurement. 80 , p. 870-909 40 p.

Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia:A 24-Week Phase 3 Study

Correll Christoph U, Newcomer John W, Silverman Bernard, DiPetrillo Lauren, Graham Christine, Jiang Ying, Du Yangchun, Simmons Adam, Hopkinson Craig, McDonnell David, Kahn René S 14 aug 2020, In: American Journal of Psychiatry. 177 , p. 1168-1178 11 p.

Altered thalamocortical structural connectivity in persons with schizophrenia and healthy siblings

Yao Beier, Neggers Sebastiaan F W, Kahn René S, Thakkar Katharine N 31 jul 2020, In: NeuroImage. Clinical. 28 , p. 1-10

The Genetics of the Mood Disorder Spectrum:Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Coleman Jonathan R.I., Gaspar Héléna A., Bryois Julien, Byrne Enda M., Forstner Andreas J., Holmans Peter A., de Leeuw Christiaan A., Mattheisen Manuel, McQuillin Andrew, Whitehead Pavlides Jennifer M., Pers Tune H., Ripke Stephan, Stahl Eli A., Steinberg Stacy, Trubetskoy Vassily, Trzaskowski Maciej, Wang Yunpeng, Abbott Liam, Abdellaoui Abdel, Adams Mark J., Adolfsson Annelie Nordin, Agerbo Esben, Akil Huda, Albani Diego, Alliey-Rodriguez Ney, Als Thomas D., Andlauer Till F.M., Anjorin Adebayo, Antilla Verneri, Van der Auwera Sandra, Awasthi Swapnil, Bacanu Silviu Alin, Badner Judith A., Bækvad-Hansen Marie, Barchas Jack D., Bass Nicholas, Bauer Michael, Beekman Aartjan T.F., Belliveau Richard, Bergen Sarah E., Bigdeli Tim B., Binder Elisabeth B., Bøen Erlend, Boks Marco, Boocock James, Budde Monika, Bunney William, Burmeister Margit, Kahn René S., Ophoff Roel A., , 15 jul 2020, In: Biological Psychiatry. 88 , p. 169-184 16 p.

Neuroharmony:A new tool for harmonizing volumetric MRI data from unseen scanners

Garcia-Dias Rafael, Scarpazza Cristina, Baecker Lea, Vieira Sandra, Pinaya Walter H L, Corvin Aiden, Redolfi Alberto, Nelson Barnaby, Crespo-Facorro Benedicto, McDonald Colm, Tordesillas-Gutiérrez Diana, Cannon Dara, Mothersill David, Hernaus Dennis, Morris Derek, Setien-Suero Esther, Donohoe Gary, Frisoni Giovanni, Tronchin Giulia, Sato João, Marcelis Machteld, Kempton Matthew, van Haren Neeltje E M, Gruber Oliver, McGorry Patrick, Amminger Paul, McGuire Philip, Gong Qiyong, Kahn René S, Ayesa-Arriola Rosa, van Amelsvoort Therese, Ortiz-García de la Foz Victor, Calhoun Vince, Cahn Wiepke, Mechelli Andrea 4 jul 2020, In: NeuroImage. 220

Lithium Use during Pregnancy and the Risk of Miscarriage

Poels Eline M P, Kamperman Astrid M, Vreeker Annabel, Gilden Janneke, Boks Marco P, Kahn René S, Ophoff Roel A, Bergink Veerle 11 jun 2020, In: Journal of Clinical medicine. 9 , p. 1-5

Gene expression and response prediction to amisulpride in the OPTiMiSE first episode psychoses

Troudet Réjane, Ali Wafa Bel Haj, Bacq-Daian Delphine, Rossum Inge Winter van, Boland-Auge Anne, Battail Christophe, Barau Caroline, Rujescu Dan, McGuire Philip, Kahn René S, Deleuze Jean-François, Leboyer Marion, Jamain Stéphane, 25 mei 2020, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 45 , p. 1637-1644 8 p.

Polygenic risk score for schizophrenia was not associated with glycemic level (HbA1c) in patients with non-affective psychosis:Genetic Risk and Outcome of Psychosis (GROUP) cohort study

Habtewold Tesfa Dejenie, Islam Md Atiqul, Liemburg Edith J., Bartels-Velthuis Agna A.A., van Beveren Nico J., Cahn Wiepke, de Haan Lieuwe, Delespaul Philippe, Meijer Carin J., Myin-Germeys Inez, Kahn Rene S., Schirmbeck Frederike, Simons Claudia J.P., van Amelsvoort Therese, van Haren Neeltje E., van Os Jim, van Winkel Ruud, Bruggeman Richard, Alizadeh Behrooz Z., 1 mei 2020, In: Journal of Psychosomatic Research. 132 , p. 1-8

Changes in the intracranial volume from early adulthood to the sixth decade of life:A longitudinal study

Caspi Yaron, Brouwer Rachel M, Schnack Hugo G, van de Nieuwenhuijzen Marieke E, Cahn Wiepke, Kahn René S, Niessen Wiro J, van der Lugt Aad, Pol Hilleke Hulshoff 24 apr 2020, In: NeuroImage. 220 , p. 1-16

Cannabinoids and psychotic symptoms:A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Boks Marco P, He Yujie, Schubart Chris D, van Gastel Willemijn, Elkrief Laurent, Huguet Guillaume, van Eijk Kristel, Vinkers Christiaan H, Kahn René S, Paus Tomás, Conrod Patricia, Hol Elly M, de Witte Lot D 21 apr 2020, In: Brain, Behavior, and Immunity. 88 , p. 573-581 9 p.

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.