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prof. dr. L.J. (Jaap) Kappelle

Full Professor
prof. dr. L.J. (Jaap) Kappelle
  • Neurologen

Research Programs

Biography

Biography

Jaap Kappelle was registered as a clinical neurologist in 1988. He obtained his PhD degree in Utrecht (1990) with Jan van Gijn. He carried out postdoctoral research at the University of Iowa, Iowa City, USA (1991) and the John P. Robarts Research Institute, London (Ontario) Canada (1998). He was appointed assistant professor at the University Utrecht in 1988, associate professor in 1994 and full professor in 2000.  He is head of the department of cerebrovascular diseases of the University Medical Centre (UMC) Utrecht.

His research is embedded in the UMC Utrecht Stroke Centre in close collaboration with the departments of neurosurgery, radiology, vascular medicine, vascular surgery, rehabilitation, clinical epidemiology, primary health care and neuropsychology. The current line of research concerns stroke, in particular the diagnosis, treatment and prognosis of patients with TIA or ischaemic stroke. As part of his research activities he is member of steering committees of reserrch proframs embedded in 'Cardio-Vasculair Onderzoek Nederland'. 

He is a member of the education committee if the Dutch Neurological Society and Dutch delegate for stroke of the European Association of Neurology. Besides his regular education duties in the UMC Utrecht, he is memeber of the board of supervisors of the Medical student Societÿ 'MSFU SAMS)

Jaap Kappelle is member elect of the European Stroke Council and premium professional silver heart memeber  of the American Heart Associatiuon. He is member of the board of directors of the Dutch Vascular Society and member of the scientific committee of ‘CardioVasculair Onderzoek Nederland’ founder of the Dutch Neurovascular Society. He is also a member of the 'Nederlandse Vereniging voor Medsich Specialistische Rappoprtages and serves as neutral expert for different courts, insurance companies and health care organisations.

 

Research line

Cerebrovascular diseases

publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=Kappelle+LJ

Side Activities

As mentioned in the Biography.

Research Output (866)

Strategic infarct locations for post-stroke cognitive impairment:a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts

Weaver Nick A., Kuijf Hugo J., Aben Hugo P., Abrigo Jill, Bae Hee Joon, Barbay Mélanie, Best Jonathan G., Bordet Régis, Chappell Francesca M., Chen Christopher P.L.H., Dondaine Thibaut, van der Giessen Ruben S., Godefroy Olivier, Gyanwali Bibek, Hamilton Olivia K.L., Hilal Saima, Huenges Wajer Irene M.C., Kang Yeonwook, Kappelle L. Jaap, Kim Beom Joon, Köhler Sebastian, de Kort Paul L.M., Koudstaal Peter J., Kuchcinski Gregory, Lam Bonnie Y.K., Lee Byung Chul, Lee Keon Joo, Lim Jae Sung, Lopes Renaud, Makin Stephen D.J., Mendyk Anne Marie, Mok Vincent C.T., Oh Mi Sun, van Oostenbrugge Robert J., Roussel Martine, Shi Lin, Staals Julie, Del C Valdés-Hernández Maria, Venketasubramanian Narayanaswamy, Verhey Frans R.J., Wardlaw Joanna M., Werring David J., Xin Xu, Yu Kyung Ho, van Zandvoort Martine J.E., Zhao Lei, Biesbroek J. Matthijs, Biessels Geert Jan 23 apr 2021, In: Lancet Neurology. 20 , p. 448-459 12 p.

Effect of intravenous thrombolysis in stroke depends on pattern of intracranial internal carotid artery calcification

Kauw Frans, de Jong Pim A, Takx Richard A P, de Jong Hugo W A M, Kappelle L Jaap, Velthuis Birgitta K, Dankbaar Jan W, jan 2021, In: Atherosclerosis. 316 , p. 8-14 7 p.

Applicability of Blood Pressure-Lowering Drug Trials to Real-World Patients With Cardiovascular Disease

Bonekamp Nadia E, Spiering Wilko, Nathoe Hendrik M, Kappelle L Jaap, de Borst Gert J, Visseren Frank L J, Westerink Jan, 2021, In: Hypertension (Dallas, Tex. : 1979). 77 , p. 357-366 10 p.

Collateral Status in Ischemic Stroke:A Comparison of Computed Tomography Angiography, Computed Tomography Perfusion, and Digital Subtraction Angiography

Kauw Frans, Dankbaar Jan W, Martin Blake W, Ding Victoria Y, Boothroyd Derek B, van Ommen Fasco, de Jong Hugo W A M, Kappelle L Jaap, Velthuis Birgitta K, Heit Jeremy J, Wintermark Max 1 nov 2020, In: Journal of Computer Assisted Tomography. 44 , p. 984-992 9 p.

Cerebral Perfusion and the Burden of Small Vessel Disease in Patients Referred to a Memory Clinic

Onkenhout Laurien, Appelmans Nadine, Kappelle L Jaap, Koek Dineke, Exalto Lieza, de Bresser Jeroen, Biessels Geert Jan, nov 2020, In: Cerebrovascular diseases (Basel, Switzerland). 49 , p. 481-486 6 p.

Early detection of small volume stroke and thromboembolic sources with computed tomography:Rationale and design of the ENCLOSE study

Kauw Frans, van Ommen Fasco, Bennink Edwin, Cramer Maarten J, Kappelle L Jaap, Takx Richard Ap, Velthuis Birgitta K, Viergever Max A, Wouter van Es H, Schonewille Wouter J, Coutinho Jonathan M, Majoie Charles Blm, Marquering Henk A, de Jong Hugo Wam, Dankbaar Jan W 23 okt 2020, In: European Stroke Journal. 5 , p. 432-440 9 p.

Cerebral Small Vessel Disease in Standard Pre-operative Imaging Reports Is Independently Associated with Increased Risk of Cardiovascular Death Following Carotid Endarterectomy

Timmerman Nathalie, Rots Marjolijn L, van Koeverden Ian D, Haitjema Saskia, van Laarhoven Constance J H C M, Vuurens Annemiek M, den Ruijter Hester M, Pasterkamp Gerard, Kappelle L Jaap, de Kleijn Dominique P V, de Borst Gert J jun 2020, In: European Journal of Vascular and Endovascular Surgery. 59 , p. 872-880 9 p.

The relation between healthy lifestyle changes and decrease in systemic inflammation in patients with stable cardiovascular disease

van ’t Klooster C. C., van der Graaf Y., Ridker P. M., Westerink J., Hjortnaes J., Sluijs I., Asselbergs F. W., Bots M. L., Kappelle L. J., Visseren F. L.J., mei 2020, In: Atherosclerosis. 301 , p. 37-43 7 p.

Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease:A 7 Tesla MRI study

Bouvy Willem H, van Veluw Susanne J, Kuijf Hugo J, Zwanenburg Jaco Jm, Kappelle Jaap L, Luijten Peter R, Koek Huiberdina L, Geerlings Mirjam I, Biessels Geert J, 1 apr 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40 , p. 739-746 8 p.

MRI Vessel Wall Imaging after Intra-Arterial Treatment for Acute Ischemic Stroke

Lindenholz A, van der Schaaf I C, van der Kolk A G, van der Worp H B, Harteveld A A, Kappelle L J, Hendrikse J apr 2020, In: American Journal of Neuroradiology. 41 , p. 624-631 8 p.

All research output

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