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prof. dr. L.J. (Jaap) Kappelle Full Professor

  • Neurology & Neurosurgery

L.J. Kappelle

Contact

Research Programs

Biography

Jaap Kappelle was registered as a clinical neurologist in 1988. He obtained his PhD degree in Utrecht (1990) with Jan van Gijn. He carried out postdoctoral research at the University of Iowa, Iowa City, USA (1991) and the John P. Robarts Research Institute, London (Ontario) Canada (1998). He was appointed assistant professor at the University Utrecht in 1988, associate professor in 1994 and full professor in 2000.  He is head of the department of cerebrovascular diseases of the University Medical Centre (UMC) Utrecht.

His research is embedded in the UMC Utrecht Stroke Centre in close collaboration with the departments of neurosurgery, radiology, vascular medicine, vascular surgery, rehabilitation, clinical epidemiology, primary health care and neuropsychology. The current line of research concerns stroke, in particular the diagnosis, treatment and prognosis of patients with TIA or ischaemic stroke. As part of his research activities he is member of steering committees of reserrch proframs embedded in 'Cardio-Vasculair Onderzoek Nederland'. 

He is a member of the education committee if the Dutch Neurological Society and Dutch delegate for stroke of the European Association of Neurology. Besides his regular education duties in the UMC Utrecht, he is memeber of the board of supervisors of the Medical student Societÿ 'MSFU SAMS)

Jaap Kappelle is member elect of the European Stroke Council and premium professional silver heart memeber  of the American Heart Associatiuon. He is member of the board of directors of the Dutch Vascular Society and member of the scientific committee of ‘CardioVasculair Onderzoek Nederland’ founder of the Dutch Neurovascular Society. He is also a member of the 'Nederlandse Vereniging voor Medsich Specialistische Rappoprtages and serves as neutral expert for different courts, insurance companies and health care organisations.

 

Research line

Cerebrovascular diseases

publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=Kappelle+LJ

Side Activities

  • As mentioned in the Biography.

Research Output (695)

Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease:A 7 Tesla MRI study

Bouvy Willem H, van Veluw Susanne J, Kuijf Hugo J, Zwanenburg Jaco Jm, Kappelle Jaap L, Luijten Peter R, Koek Huiberdina L, Geerlings Mirjam I, Biessels Geert J, apr 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40 , p. 739-746 8 p.

Frequent Cognitive Impairment in Patients With Disorders Along the Heart-Brain Axis

Hooghiemstra Astrid M, Leeuwis Anna E, Bertens Anne Suzannne, Biessels Geert Jan, Bots Michiel L, Brunner-La Rocca Hans-Peter, Greving Jacoba P, Kappelle L Jaap, van Oostenbrugge Robert J, van Rossum Albert C, van der Flier Wiesje M, 5 nov 2019, In: Stroke. 50 , p. 3369-3375 7 p.

Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease

Oudeman Eline A, Greving Jacoba P, Van den Berg-Vos Renske M, Biessels Geert Jan, Bron Esther E, van Oostenbrugge Robert, de Bresser Jeroen, Kappelle L Jaap, 22 okt 2019, In: Stroke. 50 , p. 3540-3544 5 p.

Normal-range thyroid-stimulating hormone levels and cardiovascular events and mortality in type 2 diabetes

de Vries Tamar I., de Valk Harold W., van der Graaf Yolanda, de Borst Gert J., Cramer Maarten J.M., Jaap Kappelle L., Visseren Frank L.J., Westerink Jan 16 okt 2019, In: Diabetes Research and Clinical Practice. 157

Cerebral blood flow and cognitive functioning in the heart-brain axis

Leeuwis A. E., Hooghiemstra A. M., Bron E. E., Brunner-La Rocca H. P., Kappelle L. J., Van Oostenbrugge R. J., Greving J. P., Niessen W. J., Van Buchem M. A., Van Osch M. J. P., Van Rossum A. C., Prins N. D., Biessels G. J., Barkhof F., Van der Flier W. M. okt 2019, In: European heart journal. 40 , p. 2314-2314

Candidate Biomarkers for the Diagnosis of Transient Ischemic Attack:A Systematic Review

Dolmans L. Servaas, Rutten Frans H., Koenen Niels C.T., Bartelink Marie Louise E.L., Reitsma Johannes B., Kappelle L. Jaap, Hoes Arno W. 30 aug 2019, In: Cerebrovascular Diseases. 47 , p. 207-216 10 p.

Nonfocal transient neurological attacks are related to cognitive impairment in patients with heart failure

Oudeman Eline A., Greving Jacoba P., Hooghiemstra Astrid M., Brunner-La Rocca Hans-Peter, Biessels Geert Jan, Kappelle L. Jaap, Daemen M. J., van Buchem M. A., van der Geest R. J., van Osch M. J. P., de Roos A., van der Flier W. M., van Rossum A. C., La Rocca H. P. Brunner, Ikram M. A., Koudstaal P. J., Niessen W. J., van Oostenbrugge R., Bots M. L. aug 2019, In: Journal of Neurology. 266 , p. 2035-2042 8 p.

Short-Term Double Layer Mesh Stent Patency for Emergent or Elective Carotid Artery Stenting:A Single Center Experience

De Vries Evelien E., Vonken Evert J., Kappelle L. Jaap, Toorop Raechel J., De Borst Gert J. 1 jul 2019, In: Stroke. 50 , p. 1898-1901 4 p.

Stenting for symptomatic vertebral artery stenosis: a preplanned pooled individual patient data analysis

Markus Hugh S., Harshfield Eric L., Compter Annette, Kuker Wilhelm, Kappelle L. Jaap, Clifton Andrew, van der Worp H. Bart, Rothwell Peter, Algra Ale 1 jul 2019, In: Lancet Neurology. 18 , p. 666-673 8 p.

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Wilson Duncan, Ambler Gareth, Lee Keon-Joo, Lim Jae-Sung, Shiozawa Masayuki, Koga Masatoshi, Li Linxin, Lovelock Caroline, Chabriat Hugues, Hennerici Michael, Wong Yuen Kwun, Mak Henry Ka Fung, Prats-Sanchez Luis, Martinez-Domeno Alejandro, Inamura Shigeru, Yoshifuji Kazuhisa, Arsava Ethem Murat, Horstmann Solveig, Purrucker Jan, Lam Bonnie Yin Ka, Wong Adrian, Kim Young Dae, Song Tae-Jin, Schrooten Maarten, Lemmens Robin, Eppinger Sebastian, Gattringer Thomas, Uysal Ender, Tanriverdi Zeynep, Bornstein Natan M., Ben Assayag Einor, Hallevi Hen, Tanaka Jun, Hara Hideo, Coutts Shelagh B., Hert Lisa, Polymeris Alexandros, Seiffge David J., Lyrer Philippe, Algra Ale, Kappelle Jaap, Salman Rustam Al-Shahi, Jager Hans R., Lip Gregory Y. H., Mattle Heinrich P., Panos Leonidas D., Mas Jean-Louis, Legrand Laurence, Karayiannis Christopher, Phan Thanh, 1 jul 2019, In: Lancet Neurology. 18 , p. 653-665 13 p.

All Research Output (695)
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