Back

dr. K.P. (Kevin) Kenna

dr. K.P. (Kevin) Kenna

Associate Professor
dr. K.P. (Kevin) Kenna
  • Translational Neuroscience

Research Programs

Brain

Research Output (44)

Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS

Eitan Chen, Siany Aviad, Barkan Elad, Olender Tsviya, van Eijk Kristel R, Moisse Matthieu, Farhan Sali M K, Danino Yehuda M, Yanowski Eran, Marmor-Kollet Hagai, Rivkin Natalia, Yacovzada Nancy Sarah, Hung Shu-Ting, Cooper-Knock Johnathan, Yu Chien-Hsiung, Louis Cynthia, Masters Seth L, Kenna Kevin P, van der Spek Rick A A, Sproviero William, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Jones Ashley R, Elbaz-Alon Yael, Cohen Yahel, Chapnik Elik, Rothschild Daphna, Weissbrod Omer, Beck Gilad, Ainbinder Elena, Ben-Dor Shifra, Werneburg Sebastian, Schafer Dorothy P, Brown Robert H, Shaw Pamela J, Van Damme Philip, van den Berg Leonard H, Phatnani Hemali, Segal Eran, Ichida Justin K, Al-Chalabi Ammar, Veldink Jan H, Hornstein Eran, Apr 2022, In: Nature Neuroscience. 25 , p. 433-445 13 p.

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

Hop Paul J, Zwamborn Ramona A J, Hannon Eilis, Shireby Gemma L, Nabais Marta F, Walker Emma M, van Rheenen Wouter, van Vugt Joke J F A, Dekker Annelot M, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Moisse Matthieu, Baird Denis, Al Khleifat Ahmad, Iacoangeli Alfredo, Ticozzi Nicola, Ratti Antonia, Cooper-Knock Jonathan, Morrison Karen E, Shaw Pamela J, Basak A Nazli, Chiò Adriano, Calvo Andrea, Moglia Cristina, Canosa Antonio, Brunetti Maura, Grassano Maurizio, Gotkine Marc, Lerner Yossef, Zabari Michal, Vourc'h Patrick, Corcia Philippe, Couratier Philippe, Mora Pardina Jesus S, Salas Teresa, Dion Patrick, Ross Jay P, Henderson Robert D, van Es Michael A, Pasterkamp R Jeroen, McLaughlin Russell L, Kenna Kevin P, van den Berg Leonard H, Veldink Jan H, Veldink Jan H, van den Berg Leonard H, Deelen Patrick, Deelen Patrick, Veldink Jan H, 23 Feb 2022, In: Science translational medicine. 14 , p. 1-15

Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis

Al Khleifat Ahmad, Iacoangeli Alfredo, van Vugt Joke J F A, Bowles Harry, Moisse Matthieu, Zwamborn Ramona A J, van der Spek Rick A A, Shatunov Aleksey, Cooper-Knock Johnathan, Topp Simon, Byrne Ross, Gellera Cinzia, López Victoria, Jones Ashley R, Opie-Martin Sarah, Vural Atay, Campos Yolanda, van Rheenen Wouter, Kenna Brendan, Van Eijk Kristel R, Kenna Kevin, Weber Markus, Smith Bradley, Fogh Isabella, Silani Vincenzo, Morrison Karen E, Dobson Richard, van Es Michael A, McLaughlin Russell L, Vourc'h Patrick, Chio Adriano, Corcia Philippe, de Carvalho Mamede, Gotkine Marc, Panades Monica P, Mora Jesus S, Shaw Pamela J, Landers John E, Glass Jonathan D, Shaw Christopher E, Basak Nazli, Hardiman Orla, Robberecht Wim, Van Damme Philip, van den Berg Leonard H, Veldink Jan H, Al-Chalabi Ammar 28 Jan 2022, In: npj Genomic Medicine. 7 , p. 1-8

Author Correction:Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (Nature Genetics, (2021), 53, 12, (1636-1648), 10.1038/s41588-021-00973-1)

van Rheenen Wouter, van der Spek Rick A A, Bakker Mark K, van Vugt Joke J F A, Hop Paul J, Zwamborn Ramona A J, de Klein Niek, Westra Harm-Jan, Bakker Olivier B, Deelen Patrick, Shireby Gemma, Hannon Eilis, Moisse Matthieu, Baird Denis, Restuadi Restuadi, Dolzhenko Egor, Dekker Annelot M, Gawor Klara, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Kooyman Maarten, Byrne Ross P, Doherty Mark, Heverin Mark, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Ticozzi Nicola, Cooper-Knock Johnathan, Smith Bradley N, Gromicho Marta, Chandran Siddharthan, Pal Suvankar, Morrison Karen E, Shaw Pamela J, Hardy John, Orrell Richard W, Sendtner Michael, Meyer Thomas, Başak Nazli, van der Kooi Anneke J, Ratti Antonia, Ophoff Roel A, van Es Michael A, Pasterkamp R Jeroen, McLaughlin Russell L, Kenna Kevin P, van den Berg Leonard H, Veldink Jan H, 2022, In: Nature Genetics. 54 , p. 361-361 1 p.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen Wouter, van der Spek Rick A A, Bakker Mark K, van Vugt Joke J F A, Hop Paul J, Zwamborn Ramona A J, de Klein Niek, Westra Harm-Jan, Bakker Olivier B, Deelen Patrick, Shireby Gemma, Hannon Eilis, Moisse Matthieu, Baird Denis, Restuadi Restuadi, Dolzhenko Egor, Dekker Annelot M, Gawor Klara, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Kooyman Maarten, Byrne Ross P, Doherty Mark, Heverin Mark, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Ticozzi Nicola, Cooper-Knock Johnathan, Smith Bradley N, Gromicho Marta, Chandran Siddharthan, Pal Suvankar, Morrison Karen E, Shaw Pamela J, Hardy John, Orrell Richard W, Sendtner Michael, Meyer Thomas, Başak Nazli, van der Kooi Anneke J, Ratti Antonia, Ophoff Roel A, van Es Michael A, Pasterkamp R Jeroen, McLaughlin Russell L, Kenna Kevin P, van den Berg Leonard H, Veldink Jan H, Dec 2021, In: Nature Genetics. 53 , p. 1636-1648 13 p.

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

Johnson Janel O, Chia Ruth, Miller Danny E, Li Rachel, Kumaran Ravindran, Abramzon Yevgeniya, Alahmady Nada, Renton Alan E, Topp Simon D, Gibbs J Raphael, Cookson Mark R, Sabir Marya S, Dalgard Clifton L, Troakes Claire, Jones Ashley R, Shatunov Aleksey, Iacoangeli Alfredo, Al Khleifat Ahmad, Ticozzi Nicola, Silani Vincenzo, Gellera Cinzia, Blair Ian P, Dobson-Stone Carol, Kwok John B, Bonkowski Emily S, Palvadeau Robin, Tienari Pentti J, Morrison Karen E, Shaw Pamela J, Al-Chalabi Ammar, Brown Robert H, Calvo Andrea, Mora Gabriele, Al-Saif Hind, Gotkine Marc, Leigh Fawn, Chang Irene J, Perlman Seth J, Glass Ian, Scott Anna I, Shaw Christopher E, Basak A Nazli, Landers John E, Chiò Adriano, Crawford Thomas O, Kenna Kevin P, McLaughlin Russell L, van Rheenen Wouter, Veldink Jan H, van den Berg Leonard H, 30 Aug 2021, In: JAMA Neurology. 78 , p. 1236-1248 13 p.

Advances in the genetic classification of amyotrophic lateral sclerosis

Cooper-Knock Johnathan, Harvey Calum, Zhang Sai, Moll Tobias, Timpanaro Ilia Sarah, Kenna Kevin P, Iacoangeli Alfredo, Veldink Jan H 2 Aug 2021, In: Current Opinion in Neurology. 34 , p. 756-764

Common and rare variant analyses combined with single-cell multiomics reveal cell-type-specific molecular mechanisms of COVID-19 severity

Zhang Sai, Cooper-Knock Johnathan, Weimer Annika K, Harvey Calum, Julian Thomas H, Wang Cheng, Li Jingjing, Furini Simone, Frullanti Elisa, Fava Francesca, Renieri Alessandra, Pan Cuiping, Song Jina, Billing-Ross Paul, Gao Peng, Shen Xiaotao, Timpanaro Ilia Sarah, Kenna Kevin P, Davis Mark M, Tsao Philip S, Snyder Michael P, 21 Jun 2021, p. 1-82

Genetic analysis of ALS cases in the isolated island population of Malta

Borg Rebecca, Farrugia Wismayer Maia, Bonavia Karl, Farrugia Wismayer Andrew, Vella Malcolm, van Vugt Joke J F A, Kenna Brendan J, Kenna Kevin P, Vassallo Neville, Veldink Jan H, Cauchi Ruben J Apr 2021, In: European Journal of Human Genetics. 29 , p. 604-614 11 p.

The Effect of SMN Gene Dosage on ALS Risk and Disease Severity

Moisse Matthieu, Zwamborn Ramona A J, van Vugt Joke, van der Spek Rick, van Rheenen Wouter, Kenna Brendan, Van Eijk Kristel, Kenna Kevin, Corcia Philippe, Couratier Philippe, Vourc'h Patrick, Hardiman Orla, McLaughin Russell, Gotkine Marc, Drory Vivian, Ticozzi Nicola, Silani Vincenzo, de Carvalho Mamede, Mora Pardina Jesús S, Povedano Monica, Andersen Peter M, Weber Markus, Başak Nazli A, Chen Xiao, Eberle Michael A, Al-Chalabi Ammar, Shaw Chris, Shaw Pamela J, Morrison Karen E, Landers John E, Glass Jonathan D, Robberecht Wim, van Es Michael, van den Berg Leonard, Veldink Jan, Van Damme Philip, Apr 2021, In: Annals of Neurology. 89 , p. 686-697 12 p.

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht

Contact

Emergency?

Directions

Appointments

Practical

umcutrecht.nl maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet