prof. dr. A.C. Knulst

Full Professor

  • Dermatology and Allergology

prof. dr. A.C. Knulst

Research Programs


Prof. dr. André C. Knulst is dermatologist and immunologist at the Department of Dermatology/Allergology of the UMC Utrecht. He heads the outpatient department of Allergology and  has a longstanding experience in diagnosis and treatment of patients with allergies, urticaria and angio-edema, with a particular interest in food allergy, urticaria and angio-edema. The Dept. of Dermatology/Allergology is a centre of expertise for eczema, food allergy and urticaria/angio-edema. Prof. Knulst is involved in the training of dermatologists, otolaryngologists, pediatric allergists, and clinical immunologists/internist-allergologists.

He also heads the allergy research. Within the UMC Utrecht there is a close collaboration with the department of Children’s Pulmonology and Allergology and the Center of Translational Immunology of the UMC Utrecht. His research focus is on patient profiling and improvement of food allergy diagnosis a.o. using component resolved diagnostics. He participated in many multicenter studies a.o. the EU sponsored SAFE, CREATE and Europrevall projects. Another research area of particular interest is the development of novel therapeutic options for food allergy. He was involved in the VIPES study on the efficacy and safety of epicutaneously administered peanut and the FAST study on the efficacy of subcutaneous immunotherapy using a hypoallergenic cod fish parvalbumin.


Side Activities

  • Member guideline committee immunotherapy

    2018 → …

    Member programme committee Hub Future Food Utrecht

    2016 → …

    Health council advice food allergy


    member ILSI Europe expert group ‘Prioritisation of allergenic foods with respect to public health relevance’

    2015 → …

    chair guideline chronic urticaria


    vice chair guideline food provocations


    international advisory board chronic urticaria Novartis

    2012 → …

    Advisory board immunotherapy ALK-ABELLO

    2012 → …

    Giving lectures on allergic diseases for general practitioners, otolaryngologists (in training), pediatricians (in training), immunologist-allergologists (in training), dermatologists (in training), also on the European level


Research Output (267)

Three-year follow-up after peanut food challenges:Accidental reactions in allergic children and introduction failure in tolerant children

Kansen Hannah M., Le Thuy My, Knulst André C., Gorissen Diana M.W., van der Ent Cornelis K., Meijer Yolanda, van Erp Francine C. 1 feb 2020, In: Journal of Allergy and Clinical Immunology. 145 , p. 705-707.e7

Ara h 7 isoforms share many linear epitopes:Are 3D epitopes crucial to elucidate divergent abilities?

Ehlers Anna M., Klinge Marco, Suer Waltraud, Weimann Yvonne, Knulst André C., Besa Frithjof, Le Thuy My, Otten Henny G. 1 nov 2019, In: Clinical and Experimental Allergy. 49 , p. 1512-1519 8 p.

High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema

Hofman Zonne L.M., Van West Nikki, Hack C. Erik, Knulst André C., Maas Coen, Röckmann Heike 12 jul 2019, In: Clinical and Translational Allergy. 9 5 p.

Food Allergy in Adults:Substantial Variation in Prevalence and Causative Foods Across Europe

Lyons Sarah A., Burney Peter G.J., Ballmer-Weber Barbara K., Fernandez-Rivas Montserrat, Barreales L., Clausen Michael, Dubakiene Ruta, Fernandez-Perez Cristina, Fritsche Philipp, Jedrzejczak-Czechowicz Monika, Kowalski Marek L., Kralimarkova T., Kummeling I., Mustakov Tihomir B., Lebens Ans F.M., van Os-Medendorp Harmieke, Papadopoulos Nikolaos G., Popov Todor A., Sakellariou Alexandros, Welsing Paco M.J., Potts J., Mills E. N.Clare, van Ree Ronald, Knulst André C., Le Thuy My 1 jul 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7 , p. 1920-1928.e11

Perceived triggers of asthma impair quality of life in children with asthma

Kansen Hannah M., Le Thuy My, Meijer Yolanda, Uiterwaal Cuno S.P.M., Knulst André C., van der Ent Cornelis K., van Erp Francine C. 1 jul 2019, In: Clinical and Experimental Allergy. 49 , p. 980-989 10 p.

Birch pollen allergy in Europe

Biedermann T., Winther L., Till S. J., Panzner P., Knulst A., Valovirta E. 1 jul 2019, In: Allergy: European Journal of Allergy and Clinical Immunology. 74 , p. 1237-1248 12 p.

Sesame oleosins are minor allergens

Ehlers Anna M., Rossnagel Madlen, Brix Bettina, Blankestijn Mark A., Le Thuy My, Suer Waltraud, Otten Henny G., Knulst André C. 28 jun 2019, In: Clinical and Translational Allergy. 9

Specifieke allergenen bij de diagnostiek van pinda-allergie

van Erp Francine C., Le T. M., Kansen H. M., Meijer Y., van der Ent C. K., Knol E. F., Knulst A. C. 1 apr 2019, In: Nederlands Tijdschrift voor Dermatologie en Venereologie. 29 , p. 57-59 3 p.

Praktische adviezen bij pollengerelateerde voedselallergie

Blankestijn Mark A., Le T. M., Michelsen-Huisman A. D., van Dijk A. M., Knulst A. C. 1 apr 2019, In: Nederlands Tijdschrift voor Dermatologie en Venereologie. 29 , p. 63-65 3 p.

Ernstige urticaria solaris:Licht op een nieuwe behandelmogelijkheid

van Seggelen Wouter O., Knulst A. C., Sigurdsson V., Röckmann H. 1 apr 2019, In: Nederlands Tijdschrift voor Dermatologie en Venereologie. 29 , p. 49-51 3 p.

All Research Output (267)