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prof. dr. A.C. Knulst

prof. dr. A.C. Knulst

Full Professor
prof. dr. A.C. Knulst
  • Dermatology and Allergology

Research Programs

Infection & Immunity

Biography

Biography

Prof. dr. André C. Knulst is dermatologist and immunologist at the Department of Dermatology/Allergology of the UMC Utrecht. He heads the outpatient department of Allergology and  has a longstanding experience in diagnosis and treatment of patients with allergies, urticaria and angio-edema, with a particular interest in food allergy, urticaria and angio-edema. The Dept. of Dermatology/Allergology is a centre of expertise for eczema, food allergy and urticaria/angio-edema. Prof. Knulst is involved in the training of dermatologists, otolaryngologists, pediatric allergists, and clinical immunologists/internist-allergologists.

He also heads the allergy research. Within the UMC Utrecht there is a close collaboration with the department of Children’s Pulmonology and Allergology and the Center of Translational Immunology of the UMC Utrecht. His research focus is on patient profiling and improvement of food allergy diagnosis a.o. using component resolved diagnostics. He participated in many multicenter studies a.o. the EU sponsored SAFE, CREATE and Europrevall projects. Another research area of particular interest is the development of novel therapeutic options for food allergy. He was involved in the VIPES study on the efficacy and safety of epicutaneously administered peanut and the FAST study on the efficacy of subcutaneous immunotherapy using a hypoallergenic cod fish parvalbumin.

 

Side Activities

Member guideline committee immunotherapy

2018 → …

Member programme committee Hub Future Food Utrecht

2016 → …

Health council advice food allergy

20162017

member ILSI Europe expert group ‘Prioritisation of allergenic foods with respect to public health relevance’

2015 → …

chair guideline chronic urticaria

20142016

vice chair guideline food provocations

20132016

international advisory board chronic urticaria Novartis

2012 → …

Advisory board immunotherapy ALK-ABELLO

2012 → …

Giving lectures on allergic diseases for general practitioners, otolaryngologists (in training), pediatricians (in training), immunologist-allergologists (in training), dermatologists (in training), also on the European level

2000

Research Output (291)

Systemic and local evidence for complement involvement in chronic spontaneous urticaria

Alizadeh Aghdam Mehran, van den Elzen Mignon, van Os-Medendorp Harmieke, van Dijk Marijke R, Knol Edward F, Knulst André C, Röckmann Heike, Otten Henny G jul 2021, In: Clinical and Translational Allergy. 11 , p. 1-8

Predicting the allergenicity of legume proteins using a PBMC gene expression assay

Smits Mark, Meijerink Marjolein, Le Thuy My, Knulst André, de Jong Aard, Caspers Martinus Petrus Maria, Lima Everton Souto, Babé Lilia, Ladics Gregory, McClain Scott, Houben Geert, Verhoeckx Kitty 13 apr 2021, In: BMC Immunology. 22 , p. 1-12

Fructo-Oligosaccharides Modify Human DC Maturation and Peanut-Induced Autologous T-Cell Response of Allergic Patients In Vitro

Hayen Simone M., Knulst André C., Garssen Johan, Otten Henny G., Willemsen Linette E.M. 15 feb 2021, In: Frontiers in Immunology. 11

Accidental food-allergic reactions are associated with higher costs and more sick leave but not with quality of life

Versluis Astrid, Knulst Andre C, Michelsen-Huisman Anouska D, Houben Geert F, Blom W Marty, Le Thuy-My, van Os-Medendorp Harmieke 1 feb 2021, In: Clinical and Experimental Allergy. 51 , p. 627-630 4 p.

Identification and Purification of Novel Low-Molecular-Weight Lupine Allergens as Components for Personalized Diagnostics

Jappe Uta, Karstedt Arabella, Warneke Daniela, Hellmig Saskia, Böttger Marisa, Riffelmann Friedrich W, Treudler Regina, Lange Lars, Abraham Susanne, Dölle-Bierke Sabine, Worm Margitta, Wagner Nicola, Ruëff Franziska, Reese Gerald, Knulst André C, Becker Wolf-Meinhard 28 jan 2021, In: Nutrients. 13 21 p.

Allergen labelling:Current practice and improvement from a communication perspective

Blom W Marty, van Dijk Liselotte M, Michelsen-Huisman Anouska, Houben Geert F, Knulst André C, Linders Yvette F M, Verhoeckx Kitty C M, Holleman Bregje C, Lentz Leo R 26 jan 2021, In: Clinical and Experimental Allergy. 51 , p. 574-584 11 p.

Digestion and Transport across the Intestinal Epithelium Affects the Allergenicity of Ara h 1 and 3 but Not of Ara h 2 and 6

Smits Mark, Nooijen Irene, Redegeld Frank, de Jong Aard, Le Thuy-My, Knulst André, Houben Geert, Verhoeckx Kitty 12 jan 2021, In: Molecular Nutrition & Food Research. 65 , p. e2000712

Ranking of 10 legumes according to the prevalence of sensitization as a parameter to characterize allergenic proteins

Smits Mark, Verhoeckx Kitty, Knulst André, Welsing Paco, de Jong Aard, Houben Geert, Le Thuy My jan 2021, In: Toxicology Reports. 8 , p. 767-773 7 p.

Safety and effectiveness of omalizumab for the treatment of chronic urticaria in pediatric patients

Dekkers Coco, Alizadeh Aghdam Mehran, Graaf Marlies de, Knulst André C, Meijer Yolanda, van den Reek Juul M P A, Stadermann Marike B, Röckmann Heike 2021, In: Pediatric Allergy and Immunology. 32 , p. 720-726 7 p.

IgE-binding to vicilin-like antimicrobial peptides is associated with systemic reactions to macadamia nut

Ehlers Anna M., Rohwer Stefanie, Otten Henny G., Brix Bettina, Le Thuy My, Suer Waltraud, Knulst André C. 2 dec 2020, In: Clinical and Translational Allergy. 10 , p. 1-5

All research output

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