prof. dr. ir. J.J.W. Lagendijk

Full Professor
prof. dr. ir. J.J.W. Lagendijk
  • Medical Physics Group

Research Programs

Strategic Program Cancer



Jan Lagendijk's research focus is the application of MRI in radiotherapy. MRI is used for all aspects of radiotherapy. With MRI it is possible to find and characterize tumours. Jan Lagendijk is developing the MRI linac system to visualize the tumour and its surrounding tissues, in real time, at the moment of treatment. This to guide and optimize treatment and to prevent that normal tissues are being irradiated. Jan Lagendijk also uses MRI for response assessment, to quantify the impact of treatments. His motto is ‘See what you treat’. The technology, he develops, must create the next generation radiotherapy standard. Together with Elekta and Philips he is introducing this MRI technology in routine clinic.

Side Activities

  • Member Dutch Health Council

Fellowship and Awards

  • ESHO award for life time achievement in hyperthermia

Research Output (311)

Evaluation of the radiofrequency performance of a wide-bore 1.5 T positron emission tomography/magnetic resonance imaging body coil for radiotherapy planning

Branderhorst Woutjan, Steensma Bart R., Beijst Casper, Huijing Erik R., Alborahal Cezar, Versteeg Edwin, Weissler Bjoern, Schug David, Gebhardt Pierre, Gross-Weege Nicolas, Mueller Florian, Krueger Karl, Dey Thomas, Radermacher Harald, Lips Oliver, Lagendijk Jan, Schulz Volkmar, de Jong Hugo W.A.M., Klomp Dennis W.J. apr 2021, In: Physics and Imaging in Radiation Oncology. 17 , p. 13-19 7 p.

Determining the safety of ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer:A toxicity assessment of 150 patients

van Son Marieke, Peters Max, Moerland Marinus, van de Pol Sandrine, Eppinga Wietse, Lagendijk Jan, van der Voort van Zyp Jochem mrt 2021, In: Clinical and translational radiation oncology. 27 , p. 1-7 7 p.

Deep learning-based reconstruction of in vivo pelvis conductivity with a 3D patch-based convolutional neural network trained on simulated MR data

Gavazzi Soraya, van den Berg Cornelis A.T., Savenije Mark H.F., Kok H. Petra, de Boer Peter, Stalpers Lukas J.A., Lagendijk Jan J.W., Crezee Hans, van Lier Astrid L.H.M.W. 1 nov 2020, In: Magnetic Resonance in Medicine. 84 , p. 2772-2787 16 p.

Health-related quality of life after ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer:reporting the patient's perspective

van Son Marieke, Monninkhof Evelyn, Peters Max, Lagendijk Jan, van der Voort van Zyp Jochem nov 2020, In: Clinical and translational radiation oncology. 25 , p. 81-87 7 p.

Prostate intrafraction motion during the preparation and delivery of MR-guided radiotherapy sessions on a 1.5T MR-Linac

de Muinck Keizer D. M., Kerkmeijer L. G.W., Willigenburg T., van Lier A. L.H.M.W., Hartogh M. D.den, van der Voort van Zyp J. R.N., de Groot-van Breugel E. N., Raaymakers B. W., Lagendijk J. J.W., de Boer J. C.J. okt 2020, In: Radiotherapy and Oncology. 151 , p. 88-94 7 p.

Technical feasibility of magnetic resonance fingerprinting on a 1.5T MRI-linac

Bruijnen Tom, van der Heide Oscar, Intven Martijn P W, Mook Stella, Lagendijk Jan J W, Van den Berg Cornelis A T, Tijssen Rob H N 25 sep 2020, In: Physics in medicine and biology. 65

Problems and Promises of Introducing the Magnetic Resonance Imaging Linear Accelerator Into Routine Care:The Case of Prostate Cancer

Hehakaya Charisma, Van der Voort van Zyp Jochem R, Lagendijk Jan J W, Grobbee Diederick E, Verkooijen Helena M, Moors Ellen H M 2 sep 2020, In: Frontiers in oncology. 10 11 p.

Optimizing MR-Guided Radiotherapy for Breast Cancer Patients

Koerkamp Maureen L. Groot, Vasmel Jeanine E., Russell Nicola S., Shaitelman Simona F., Anandadas Carmel N., Currey Adam, Vesprini Danny, Keller Brian M., De-Colle Chiara, Han Kathy, Braunstein Lior Z., Mahmood Faisal, Lorenzen Ebbe L., Philippens Marielle E. P., Verkooijen Helena M., Lagendijk Jan J. W., Houweling Antonetta C., van den Bongard H. J. G. Desiree, Kirby Anna M. 28 jul 2020, In: Frontiers in oncology. 10 , p. 1107 13 p.

Improving the imaging performance of the 1.5 T MR-linac using a flexible, 32-channel, on-body receive array

Zijlema Stefan Emiel, Tijssen Rob H N, van Dijk Luca, Hackett Sara L, Wolthaus Jochem W H, Breimer Wico, Lagendijk Jan J W, Van den Berg Cornelis A T 22 jul 2020, In: Physics in medicine and biology. 65 , p. 215008

Image guidance in radiation therapy for better cure of cancer

Grégoire Vincent, Guckenberger Matthias, Haustermans Karin, Lagendijk Jan J.W., Ménard Cynthia, Pötter Richard, Slotman Ben J., Tanderup Kari, Thorwarth Daniela, van Herk Marcel, Zips Daniel 1 jul 2020, In: Molecular Oncology. 14 , p. 1470-1491 22 p.

All research output