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prof. dr. ir. J.J.W. Lagendijk

prof. dr. ir. J.J.W. Lagendijk

Full Professor
prof. dr. ir. J.J.W. Lagendijk
  • Radiology

Research Programs

Strategic Program Cancer

Biography

Biography

Jan Lagendijk's research focus is the application of MRI in radiotherapy. MRI is used for all aspects of radiotherapy. With MRI it is possible to find and characterize tumours. Jan Lagendijk is developing the MRI linac system to visualize the tumour and its surrounding tissues, in real time, at the moment of treatment. This to guide and optimize treatment and to prevent that normal tissues are being irradiated. Jan Lagendijk also uses MRI for response assessment, to quantify the impact of treatments. His motto is ‘See what you treat’. The technology, he develops, must create the next generation radiotherapy standard. Together with Elekta and Philips he is introducing this MRI technology in routine clinic.

 

See here a movie explaining MR Linac >

See here the UMCU page of Radiotherapy >

Side Activities

Not applicable.

Fellowship and Awards

ESHO award for life time achievement in hyperthermia

Research Output (332)

Accumulated bladder wall dose is correlated with patient-reported acute urinary toxicity in prostate cancer patients treated with stereotactic, daily adaptive MR-guided radiotherapy

Willigenburg Thomas, van der Velden Joanne M., Zachiu Cornel, Teunissen Frederik R., Lagendijk Jan J.W., Raaymakers Bas W., de Boer Johannes C.J., van der Voort van Zyp Jochem R.N. Jun 2022, In: Radiotherapy and Oncology. 171 , p. 182-188 7 p.

A mask-compatible, radiolucent, 8-channel head and neck receive array for MRI-guided radiotherapy treatments and pre-treatment simulation

Zijlema Stefan Emiel, Breimer Wico, Gosselink Mark W J M, Bruijnen Tom, Arteaga de Castro Catalina S, Tijssen Rob H N, Lagendijk Jan J W, Philippens Marielle E P, Van den Berg Cornelis A T 11 May 2022, In: Physics in medicine and biology. 67 , p. 1-14

Clinical implementation and feasibility of long-course fractionated MR-guided chemoradiotherapy for patients with esophageal cancer:An R-IDEAL stage 1b/2a evaluation of technical innovation

Boekhoff M. R., Bouwmans R., Doornaert P. A.H., Intven M. P.W., Lagendijk J. J.W., van Lier A. L.H.M.W., Rasing M. J.A., van de Ven S., Meijer G. J., Mook S. May 2022, In: Clinical and translational radiation oncology. 34 , p. 82-89 8 p.

Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Vasmel Jeanine E., Groot Koerkamp Maureen L., Mandija Stefano, Veldhuis Wouter B., Moman Maaike R., Froeling Martijn, van der Velden Bas H.M., Charaghvandi Ramona K., Vreuls Celien P.H., van Diest Paul J., van Leeuwen A. M.Gijs, van Gorp Joost, Philippens Marielle E.P., van Asselen Bram, Lagendijk Jan J.W., Verkooijen Helena M., van den Bongard H. J.G.Desirée, Houweling Antonetta C. 8 Apr 2022, In: Advances in Radiation Oncology. 7 , p. 1-11

Value of Targeted Biopsies and Combined PSMA PET/CT and mp-MRI Imaging in Locally Recurrent Prostate Cancer after Primary Radiotherapy

Rasing Marnix, van Son Marieke, Moerland Marinus, de Keizer Bart, Wessels Frank, Jonges Trudy, van de Pol Sandrine, Eppinga Wietse, Noteboom Juus, Lagendijk Jan, van der Voort van Zijp Jochem, Peters Max 1 Feb 2022, In: Cancers. 14 , p. 1-13

Fast and accurate deformable contour propagation for intra-fraction adaptive magnetic resonance-guided prostate radiotherapy

Willigenburg Thomas, Zachiu Cornel, Lagendijk Jan J W, van der Voort van Zyp Jochem R N, de Boer Hans C J, Raaymakers Bas W Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 62-65 4 p.

Conventional radical versus focal treatment for localised prostate cancer:a propensity score weighted comparison of 6-year tumour control

van Son Marieke J., Peters Max, Reddy Deepika, Shah Taimur T., Hosking-Jervis Feargus, Robinson Stephen, Lagendijk Jan J.W., Mangar Stephen, Dudderidge Tim, McCracken Stuart, Hindley Richard G., Emara Amr, Nigam Raj, Persad Raj, Virdi Jaspal, Lewi Henry, Moore Caroline, Orczyk Clement, Emberton Mark, Arya Manit, Ahmed Hashim U., van der Voort van Zyp Jochem R.N., Winkler Matt, Falconer Alison Dec 2021, In: Prostate cancer and prostatic diseases. 24 , p. 1120-1128 9 p.

Minimizing the need for coil attenuation correction in integrated PET/MRI at 1.5 T using low-density MR-linac receive arrays

Zijlema Stefan Emiel, Branderhorst Woutjan, Bastiaannet Remco, Tijssen Rob H N, Lagendijk Jan J W, Van den Berg Cornelis A T 27 Sep 2021, In: Physics in medicine and biology. 66 , p. 1-12 12 p.

Seminal vesicle intrafraction motion during the delivery of radiotherapy sessions on a 1.5 T MR-Linac

De D. M. Muinck Keizer, Willigenburg T., Van J. R. N. der Voort van Zyp, Raaymakers B. W., Lagendijk J. J. W., De J. C. J. Boer Sep 2021, In: Radiotherapy and Oncology. 162 , p. 162-169 8 p.

Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer

Willigenburg Thomas, van Son Marieke J, van de Pol Sandrine M G, Eppinga Wietse S C, Lagendijk Jan J W, de Boer Hans C J, Moerland Marinus A, van der Voort van Zyp Jochem R N, Peters Max Sep 2021, In: Clinical and translational radiation oncology. 30 , p. 7-14 8 p.

All research output

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