prof. dr. ir. J.J.W. Lagendijk

prof. dr. ir. J.J.W. Lagendijk

Professor Emeritus
prof. dr. ir. J.J.W. Lagendijk
  • Imaging - research

Research Programs




Jan Lagendijk's research focus is the application of MRI in radiotherapy. MRI is used for all aspects of radiotherapy. With MRI it is possible to find and characterize tumours. Jan Lagendijk is developing the MRI linac system to visualize the tumour and its surrounding tissues, in real time, at the moment of treatment. This to guide and optimize treatment and to prevent that normal tissues are being irradiated. Jan Lagendijk also uses MRI for response assessment, to quantify the impact of treatments. His motto is ‘See what you treat’. The technology, he develops, must create the next generation radiotherapy standard. Together with Elekta and Philips he is introducing this MRI technology in routine clinic.


See here a movie explaining MR Linac >

See here the UMCU page of Radiotherapy >

Side Activities

Not applicable.

Fellowship and Awards

ESHO award for life time achievement in hyperthermia

Research Output (338)

Intrafraction motion analysis in online adaptive radiotherapy for esophageal cancer

Boekhoff Mick R, Lagendijk Jan J W, van Lier Astrid L H M W, Mook Stella, Meijer Gert J Apr 2023, In: Physics and Imaging in Radiation Oncology. 26 , p. 1-4

Recurrence characteristics after focal salvage HDR brachytherapy in prostate cancer

Rasing Marnix J.A., Peters Max, van Son Marieke, Moerland Marinus A., Eppinga Wietse, van de Pol Sandrine M.G., Noteboom Juus, Lagendijk Jan, van der Voort van Zyp Jochem R.N. Mar 2023, In: Radiotherapy and Oncology. 180 7 p.

ESTRO Breur lecture 2022:Real-time MRI-guided radiotherapy: The next generation standard?

Lagendijk Jan J W, Raaymakers Bas W, Intven Martijn P W, van der Voort van Zyp Jochem R N Nov 2022, In: Radiotherapy & Oncology. 176 , p. 244-248 5 p.

Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief

Rasing Marnix J.A., Peters Max, Moerland M. A., Noteboom Juus L., Lagendijk Jan J., van der Voort van Zyp Jochem R.N. 5 Oct 2022, In: Nederlands Tijdschrift voor Geneeskunde. 166

Clinical application of a sub-fractionation workflow for intrafraction re-planning during prostate radiotherapy treatment on a 1.5 Tesla MR-Linac:A practical method to mitigate intrafraction motion

Willigenburg Thomas, Zachiu Cornel, Bol Gijsbert H, de Groot-van Beugel Eline N, Lagendijk Jan J W, van der Voort van Zyp Jochem R N, Raaymakers Bas W, de Boer Johannes C J 14 Sep 2022, In: Radiotherapy & Oncology. 176 , p. 25-30 6 p.

Accumulated bladder wall dose is correlated with patient-reported acute urinary toxicity in prostate cancer patients treated with stereotactic, daily adaptive MR-guided radiotherapy

Willigenburg Thomas, van der Velden Joanne M., Zachiu Cornel, Teunissen Frederik R., Lagendijk Jan J.W., Raaymakers Bas W., de Boer Johannes C.J., van der Voort van Zyp Jochem R.N. Jun 2022, In: Radiotherapy and Oncology. 171 , p. 182-188 7 p.

A mask-compatible, radiolucent, 8-channel head and neck receive array for MRI-guided radiotherapy treatments and pre-treatment simulation

Zijlema Stefan Emiel, Breimer Wico, Gosselink Mark W J M, Bruijnen Tom, Arteaga de Castro Catalina S, Tijssen Rob H N, Lagendijk Jan J W, Philippens Marielle E P, Van den Berg Cornelis A T 11 May 2022, In: Physics in medicine and biology. 67 , p. 1-14

Clinical implementation and feasibility of long-course fractionated MR-guided chemoradiotherapy for patients with esophageal cancer:An R-IDEAL stage 1b/2a evaluation of technical innovation

Boekhoff M. R., Bouwmans R., Doornaert P. A.H., Intven M. P.W., Lagendijk J. J.W., van Lier A. L.H.M.W., Rasing M. J.A., van de Ven S., Meijer G. J., Mook S. May 2022, In: Clinical and translational radiation oncology. 34 , p. 82-89 8 p.

Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Vasmel Jeanine E., Groot Koerkamp Maureen L., Mandija Stefano, Veldhuis Wouter B., Moman Maaike R., Froeling Martijn, van der Velden Bas H.M., Charaghvandi Ramona K., Vreuls Celien P.H., van Diest Paul J., van Leeuwen A. M.Gijs, van Gorp Joost, Philippens Marielle E.P., van Asselen Bram, Lagendijk Jan J.W., Verkooijen Helena M., van den Bongard H. J.G.Desirée, Houweling Antonetta C. 8 Apr 2022, In: Advances in Radiation Oncology. 7 , p. 1-11

Value of Targeted Biopsies and Combined PSMA PET/CT and mp-MRI Imaging in Locally Recurrent Prostate Cancer after Primary Radiotherapy

Rasing Marnix, van Son Marieke, Moerland Marinus, de Keizer Bart, Wessels Frank, Jonges Trudy, van de Pol Sandrine, Eppinga Wietse, Noteboom Juus, Lagendijk Jan, van der Voort van Zijp Jochem, Peters Max 1 Feb 2022, In: Cancers. 14 , p. 1-13

All research output

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