prof. dr. L.P.H. (Luke) Leenen

prof. dr. L.P.H. (Luke) Leenen

Full Professor
prof. dr. L.P.H. (Luke) Leenen
  • Division of Surgical Specialties

Research Programs

Infection & Immunity



Luke PH Leenen (1957) graduated from medical school of the Radboud University in Nijmegen in 1982. From 1980 until 1985 he was a research fellow in the anatomical department of the Radboud University. He earned his PhD (1985) in basic neuroanatomical research on an electron microscopical analysis of the pyramidal tract of the rat.

From 1985 until 1988 he trained as a surgical resident at the Radboud University Hospital Nijmegen (Program director: Prof de Boer, later Prof Goris). He continued (1988-1991) his training in the Elisabeth Hospital Tilburg (Prof van Vroonhoven, later Prof vd Werken). After completion of his residency he visited Prof Waneboo in Providence for a oncology fellowship, followed by a AO fellowship in Chur (CH) with Prof Ruedi. From 1992 on he was staff surgeon at the Canisius Hospital Nijmegen responsible for Trauma and was appointed director of the Emergency Department.

From June 1993 he returned to Tilburg as a staff surgeon responsible for Trauma and Intensive Care.
He went to Utrecht in 1999 as a staff surgeon for Trauma and Intensive Care. He is the director for Surgical Intensive Care (until 2005), Emergency Department (until 2012) and the Major Incident Hospital (Calamiteitenhospitaal) (until 2021). In 2000 he was appointed professor of “Integral quality management in hospitals”. In 2002 he was appointed Professor of Trauma, Intensive Care and Acute Care Surgery.

He holds the position as chair of the trauma department and is the medical manager of the Traumacenter and local trauma registry.

Side Activities

Secretary of the Dutch Trauma Society (1993-1999)

Founding board member and secretary of the European Trauma Society (currently ESTES). European Society of Trauma and Emergency Surgery  ( past president

Board member of the World Coalition for the care of Trauma. 
Founding father of the Dutch ATLS foundation.

Chairman of the Dutch Advanced Life Support Group (until 2017)

Chaiman of the MedicALS foundation (until Dec 2021)

Member of the supervisory board of the Regional Ambulance service (RAVU) (until 2015).
Part of the group reengineering the Dutch Medical Disaster organization (GHOR) (1995-1999)

Founder of the Dutch Trauma Registry

Chair of the Scientific board of the Dutch Trauma Registry, Landelijk Netwerk Acute Zorg

Member of the Dutch National Traumacenter Advisory board, Landelijk Netwerk Acute Zorg

Member of the advisory board of the Centre of Trauma research of the Ulm University Germany

Associate editor European Journal of Trauma and Emergency Surgery

Member of the editorial board of Journal of Trauma and emergency surgery and Der Unfallchirurg

Research Output (371)

Outcomes of the resuscitative and emergency thoracotomy at a Dutch level-one trauma center:are there predictive factors for survival?

Sam A. S.Y., Nawijn F., Benders K. E.M., Houwert R. M., Leenen L. P.H., Hietbrink F. Dec 2022, In: European Journal of Trauma and Emergency Surgery. 48 , p. 4877-4887 11 p.

Visualization of the inflammatory response to injury by neutrophil phenotype categories:Neutrophil phenotypes after trauma

de Fraiture Emma J, Bongers Suus H, Jukema Bernard N, Koenderman Leo, Vrisekoop Nienke, van Wessem Karlijn J P, Leenen Luke P H, Hietbrink Falco 8 Nov 2022, In: European Journal of Trauma and Emergency Surgery. 49 , p. 1023-1034 12 p.

The potential value of observational studies of elective surgical interventions using routinely collected data

Ochen Yassine, Gademan Maaike Gj, Nelissen Rob Ghh, Poolman Rudolf W, Leenen Luke pH, Houwert R Marijn, Groenwold Rolf Hh 14 Oct 2022, In: Annals of epidemiology. 76 , p. 13-19 7 p.

Longitudinal assessment of the inflammatory response:The next step in personalized medicine after severe trauma

de Fraiture E J, Vrisekoop N, Leenen L P H, van Wessem K J P, Koenderman L, Hietbrink F 20 Sep 2022, In: Frontiers in medicine. 9 , p. 1-9

Variation of in-hospital trauma team staffing:new resuscitation, new team

van Maarseveen Oscar E.C., Huijsmans Roel L.N., Leenen Luke P.H., Ham Wietske H.W. 15 Sep 2022, In: BMC Emergency Medicine. 22 , p. 1-6

Evaluation of validity and reliability of video analysis and live observations to assess trauma team performance

van Maarseveen Oscar E C, Ham Wietske H W, van Cruchten Stijn, Duhoky Rauand, Leenen Luke P H 11 Jul 2022, In: European Journal of Trauma and Emergency Surgery. 48 , p. 4797-4803 7 p.

How to assess applicability and methodological quality of comparative studies of operative interventions in orthopedic trauma surgery

Luijken Kim, van de Wall Bryan J M, Hooft Lotty, Leenen Luke P H, Houwert R Marijn, Groenwold Rolf H H, 9 Jul 2022, In: European Journal of Trauma and Emergency Surgery. 48 , p. 4943-4953 11 p.

Trauma Resuscitation Training:An Evaluation of Nurses' Knowledge

Chowdhury Sharfuddin, Almarhabi Maha, Varghese Benish, Leenen Luke 1 Jul 2022, In: Journal of trauma nursing : the official journal of the Society of Trauma Nurses. 29 , p. 192-200 9 p.

Shift of Neutrophils From Blood to Bone Marrow Upon Extensive Experimental Trauma Surgery

Teuben Michel P.J., Heeres Marjolein, Blokhuis Taco, Spijkerman Roy, Knot Eric, Vrisekoop Nienke, Pfeifer Roman, Pape Hans Christoph, Koenderman Leo, Leenen Luke P.H. 17 May 2022, In: Frontiers in Immunology. 13 , p. 1-13

Geriatric Falls:A Registry-Based Study in the Netherlands

Verbeek Frank H.O., Ham Wietske H.W., Verbeek André L.M., de Man-van Ginkel Janneke M., van Os-Medendorp Harmieke, Westers Paul, Leenen Luke P.H. 1 May 2022, In: Journal of Trauma Nursing. 29 , p. 111-118 8 p.

All research output

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