prof. dr. L.P.H. (Luke) Leenen

prof. dr. L.P.H. (Luke) Leenen

Full Professor
prof. dr. L.P.H. (Luke) Leenen
  • Division of Surgical Specialties

Research Programs

Infection & Immunity



Luke PH Leenen (1957) graduated from medical school of the Radboud University in Nijmegen in 1982. From 1980 until 1985 he was a research fellow in the anatomical department of the Radboud University. He earned his PhD (1985) in basic neuroanatomical research on an electron microscopical analysis of the pyramidal tract of the rat.

From 1985 until 1988 he trained as a surgical resident at the Radboud University Hospital Nijmegen (Program director: Prof de Boer, later Prof Goris). He continued (1988-1991) his training in the Elisabeth Hospital Tilburg (Prof van Vroonhoven, later Prof vd Werken). After completion of his residency he visited Prof Waneboo in Providence for a oncology fellowship, followed by a AO fellowship in Chur (CH) with Prof Ruedi. From 1992 on he was staff surgeon at the Canisius Hospital Nijmegen responsible for Trauma and was appointed director of the Emergency Department.

From June 1993 he returned to Tilburg as a staff surgeon responsible for Trauma and Intensive Care.
He went to Utrecht in 1999 as a staff surgeon for Trauma and Intensive Care. He is the director for Surgical Intensive Care (until 2005), Emergency Department (until 2012) and the Major Incident Hospital (Calamiteitenhospitaal) (until 2021). In 2000 he was appointed professor of “Integral quality management in hospitals”. In 2002 he was appointed Professor of Trauma, Intensive Care and Acute Care Surgery.

He holds the position as chair of the trauma department and is the medical manager of the Traumacenter and local trauma registry.

Side Activities

Secretary of the Dutch Trauma Society (1993-1999)

Founding board member and secretary of the European Trauma Society (currently ESTES). European Society of Trauma and Emergency Surgery  ( past president

Board member of the World Coalition for the care of Trauma. 
Founding father of the Dutch ATLS foundation.

Chairman of the Dutch Advanced Life Support Group (until 2017)

Chaiman of the MedicALS foundation (until Dec 2021)

Member of the supervisory board of the Regional Ambulance service (RAVU) (until 2015).
Part of the group reengineering the Dutch Medical Disaster organization (GHOR) (1995-1999)

Founder of the Dutch Trauma Registry

Chair of the Scientific board of the Dutch Trauma Registry, Landelijk Netwerk Acute Zorg

Member of the Dutch National Traumacenter Advisory board, Landelijk Netwerk Acute Zorg

Member of the advisory board of the Centre of Trauma research of the Ulm University Germany

Associate editor European Journal of Trauma and Emergency Surgery

Member of the editorial board of Journal of Trauma and emergency surgery and Der Unfallchirurg

Research Output (365)

Longitudinal assessment of the inflammatory response:The next step in personalized medicine after severe trauma

de Fraiture E J, Vrisekoop N, Leenen L P H, van Wessem K J P, Koenderman L, Hietbrink F 20 Sep 2022, In: Frontiers in medicine. 9 , p. 1-9

Variation of in-hospital trauma team staffing:new resuscitation, new team

van Maarseveen Oscar E.C., Huijsmans Roel L.N., Leenen Luke P.H., Ham Wietske H.W. 15 Sep 2022, In: BMC Emergency Medicine. 22 , p. 1-6

Trauma Resuscitation Training:An Evaluation of Nurses' Knowledge

Chowdhury Sharfuddin, Almarhabi Maha, Varghese Benish, Leenen Luke 1 Jul 2022, In: Journal of trauma nursing : the official journal of the Society of Trauma Nurses. 29 , p. 192-200 9 p.

Shift of Neutrophils From Blood to Bone Marrow Upon Extensive Experimental Trauma Surgery

Teuben Michel P.J., Heeres Marjolein, Blokhuis Taco, Spijkerman Roy, Knot Eric, Vrisekoop Nienke, Pfeifer Roman, Pape Hans Christoph, Koenderman Leo, Leenen Luke P.H. 17 May 2022, In: Frontiers in Immunology. 13 , p. 1-13

Geriatric Falls:A Registry-Based Study in the Netherlands

Verbeek Frank H.O., Ham Wietske H.W., Verbeek André L.M., de Man-van Ginkel Janneke M., van Os-Medendorp Harmieke, Westers Paul, Leenen Luke P.H. 1 May 2022, In: Journal of Trauma Nursing. 29 , p. 111-118 8 p.

Severe isolated injuries have a high impact on resource use and mortality:a Dutch nationwide observational study

Driessen Mitchell L S, de Jongh Mariska A C, Sturms Leontien M, Bloemers Frank W, Ten Duis Henk Jan, Edwards Michael J R, Hartog Dennis den, Leenhouts Peter A, Poeze Martijn, Schipper Inger B, Spanjersberg Richard W, Wendt Klaus W, de Wit Ralph J, van Zutphen Stefan W A M, Leenen Luke P H 21 Apr 2022, In: European Journal of Trauma and Emergency Surgery. 48 , p. 4267-4276 10 p.

Outcomes of Trauma Patients Present to the Emergency Department with a Shock Index of ≥1.0

Chowdhury Sharfuddin, Parameaswari P J, Leenen Luke 4 Apr 2022, In: Journal of emergencies, trauma, and shock. 15 , p. 17-22 6 p.

Computed Tomography-Based L1 Bone Mineral Density in 624 Dutch Trauma Patients-Are North American Reference Values Valid in Europe?

Kobes Tim, Sweet Arthur, Verstegen Sophie, Houwert Marijn, Veldhuis Wouter, Leenen Luke, de Jong Pim, van Baal Mark 16 Mar 2022, In: Journal of Personalized Medicine. 12

Evaluating pre-hospital triage and decision-making in patients who died within 30 days post-trauma:A multi-site, multi-center, cohort study

Lokerman Robin D, Waalwijk Job F, van der Sluijs Rogier, Houwert Roderick M, Leenen Luke P H, van Heijl Mark, 4 Mar 2022, In: Injury. 53 , p. 1699-1706 8 p.

Physiology dictated treatment after severe trauma:timing is everything

van Wessem Karlijn J P, Leenen Luke P H, Hietbrink Falco 26 Feb 2022, In: European Journal of Trauma and Emergency Surgery. 48 , p. 3969-3979 11 p.

All research output

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