dr. A.T. (Titia) Lely

dr. A.T. (Titia) Lely

Full Professor
  • Birth Center Obstetrics - Medical

Research Programs



With the combination of a PhD in Nephrology (UMCG) and Post-doctoral training in preeclampsia field (Harvard), Titia Levy developed a unique translational research line with focus on the kidney during and after hypertensive-complicated pregnancies within Cardiovascular research line of the UMC Utrecht.

Her clinical work as gynaecologist in the Obstetrical department has its focus on Maternal Medicine and especially care for pregnancy in women with kidney disease. As young-PI, she works in close collaboration with the department of Nephrology, Vascular Medicine and Epidemiology (Julius Center). Furthermore, as a result of her post-doctoral period in Groningen several projects are in close collaboration with the UMCG.

It is her aim to improve patient care during and after pregnancy for cardiovascular and renal patients. With her translational research line mainly focussing on the kidney and vascular bed, she hopes to improve with research from bench to bedside and vice-versa renal and pregnancy outcomes in the long run.

Side Activities

Elective fellowship Maternal and Fetal Medicine at Mount Sinai Hospital

Fellowship and Awards

Dutch Kidney Foundation, Innovation grant, € 100.000 (2017)

ZonMW, Clinical fellowship, personal carrier grant € 160.000 (2013) 
Dutch Kidney Foundation, Kolff, personal junior post-doc grant € 170.000 (2011)
Personal MD/PhD Grant - UMCG - K. Holwerda - Hydrogen sulphide: a gas as therapy for PE?
(Lely: supervisor), 170.000 euro, co-PI (2011) 
Mandem Stipendium, personal post-doc grant UMCG € 100.000 (2010)
Personal MD/PhD Grant - UMCG - A.M. van der Graaf - Vascular and renal alterations in relation
to PE: from prediction to renal disease with focus on the AT-1 receptor (Lely: supervisor), 170.000 euro, co-PI (2010)

Research Output (89)

From Molecules to Imaging:Assessment of Placental Hypoxia Biomarkers in Placental Insufficiency Syndromes

Al Darwish Fatimah M, Meijerink Lotte, Coolen Bram F, Strijkers Gustav J, Bekker Mireille, Lely Titia, Terstappen Fieke 17 Aug 2023, In: Cells. 12

Nanomedicines:An approach to treat placental insufficiency and the current challenges

van Kammen C M, van Woudenberg S J, Schiffelers R, Terstappen F, Lely A T 20 Jun 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 360 , p. 57-68 12 p.

Statins in pre-eclampsia or fetal growth restriction:A systematic review and meta-analysis on maternal blood pressure and fetal growth across species

Meijerink Lotte, Wever Kim E., Terstappen Fieke, Ganzevoort Wessel, Lely A. Titia, Depmann Martine May 2023, In: BJOG: An International Journal of Obstetrics and Gynaecology. 130 , p. 577-585 9 p.

OPtimal TIming of antenatal COrticosteroid administration in pregnancies complicated by early-onset fetal growth REstriction (OPTICORE):study protocol of a multicentre, retrospective cohort study

van de Meent Mette, Kleuskens Dianne G, Ganzevoort Wessel, Gordijn Sanne J, Kooi Elisabeth M W, Onland Wes, van Rijn Bas B, Duvekot Johannes J, Kornelisse René F, Al-Nasiry Salwan, Jellema Reint K, Knol H Marieke, Manten Gwendolyn T R, Mulder-de Tollenaer Susanne M, Derks Jan B, Groenendaal Floris, Bekker Mireille N, Schuit Ewoud, Lely A Titia, Kooiman Judith 17 Mar 2023, In: BMJ Open. 13

Optimizing cardiovascular risk assessment and registration in a developing cardiovascular learning health care system:Women benefit most

Groenhof T Katrien J, Haitjema Saskia, Lely A Titia, Grobbee Diederick E, Asselbergs Folkert W, Bots Michiel L, 8 Feb 2023, In: PLOS digital health. 2

Telemonitoring for COVID-19 positive pregnant women; feasibility and user experience of SAFE@home Corona:prospective pilot study

Moes Shinta L, Depmann Martine, Lely Titia A, Bekker Mireille N Dec 2022, In: BMC Pregnancy and Childbirth. 22

A nationwide Dutch cohort study shows relatively good pregnancy outcomes after kidney transplantation and finds risk factors for adverse outcomes

Gosselink Margriet E, van Buren Marleen C, Kooiman Judith, Groen Henk, Ganzevoort Wessel, van Hamersvelt Henk W, van der Heijden Olivier W H, van de Wetering Jacqueline, Lely A Titia Oct 2022, In: Kidney International. 102 , p. 866-875 10 p.

Menstrual problems in chronic immune thrombocytopenia:A monthly challenge - a cohort study and review

van Dijk Wobke E M, Punt Marieke C, van Galen Karin P M, van Leeuwen Jeanette, Lely A Titia, Schutgens Roger E G 3 Jun 2022, In: British Journal of Haematology. 198 , p. 753-764 12 p.

Cardiometabolic Profiles in Women with a History of Hypertensive and Normotensive Fetal Growth Restriction

Bijl Rianne C, Cornette Jérôme M J, Vasak Blanka, Franx Arie, Lely A Titia, Bots Michiel L, van Rijn Bas B, Koster Maria P H 12 Jan 2022, In: Journal of Women's Health. 31 , p. 63-70 8 p.

Differential effects of renin-angiotensine-aldosteron system inhibition, sympathoinhibition and low sodium diet on blood pressure in women with a history of preeclampsia:A double-blind, placebo-controlled cross-over trial (the PALM study)

Zoet Gerbrand A, Paauw Nina D, Veerbeek Jan H W, Groenhof T Katrien J, Spiering Wilko, Verhaar Marianne C, Franx A, Titia Lely A 6 Jan 2022, In: Pregnancy Hypertension. 27 , p. 173-175 3 p.

All research output

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