prof. dr. ir. J. Malda Full Professor
- Department of Orthopaedics
- Department of Orthopaedics
Contact
jmalda@umcutrecht.nl
Research Programs
Biography
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Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing.
Areas of interest
- Joint regeneration
- Biofabrication- Biomaterial development
- Bioreactors
- Extracellular matrix-derived scaffolds
- Nutrient limitation
Side Activities
International Society for Biofabrication (ISBF), President
International Cartilage Repair Society (ICRS), General Board member, Fellow member and Chair of Basic Science Committee
Professor of Biofabrication in Translational Regenerative Medicine (0.3FTE), Department of Equine Sciences, Utrecht University
Former President of the International Society for Biofabrication (ISBF)
Co-chair of the international Conference on Biofabrication 2015
Fellowship and Awards
Anna Prize 2017, Anna Foundation and Nederlandse Orthopaedische Vereniging
Nanonica Prize 2015 for the breakthrough of the year in the field of nanotechnology, Nanonica Europe
ERC Consolidator Grant ERC-2014-CoG_647426
NWO Veni Fellowship: Printen van levend kraakbeen
Research Output (128)
Kristen Marleen, Ainsworth Madison J., Chirico Nino, van der Ven Casper F.T., Doevendans Pieter A., Sluijter Joost P.G., Malda Jos, van Mil Alain, Castilho Miguel 11 okt 2019, In: Advanced Healthcare Materials. 9 21 p.
Martin Ivan, Malda Jos, Rivron Nicolas C. 1 okt 2019, In: Current Opinion in Organ Transplantation. 24 , p. 562-567 6 p.
Malda Jos, Groll Jürgen, van Weeren P. René okt 2019, In: Nature Reviews Rheumatology. 15 , p. 571-572 2 p.
Klotz Barbara J, Oosterhoff Loes A, Utomo Lizette, Lim Khoon S, Vallmajo-Martin Queralt, Clevers Hans, Woodfield Tim B F, Rosenberg Antoine J W P, Malda Jos, Ehrbar Martin, Spee Bart, Gawlitta Debby 12 aug 2019, In: Advanced Healthcare Materials. 8
Mancini I A D, Rieppo L, Pouran B, Afara I O, Braganca F M Serra, van Rijen M H P, Kik M, Weinans H, Toyras J, van Weeren P R, Malda J 3 jul 2019, In: Bone. 127 , p. 664-673 10 p.
Nykänen Olli, Sarin Jaakko K, Ketola Juuso H, Leskinen Henri, Te Moller Nikae C R, Tiitu Virpi, Mancini Irina A D, Visser Jetze, Brommer Harold, René van Weeren P, Malda Jos, Töyräs Juha, Nissi Mikko J 2 jul 2019, In: Osteoarthritis and Cartilage. 27 , p. 1481-1490 10 p.
Visser Jetze, Melchels Ferry P W, Weinans Harrie, Kruyt Moyo C, Malda Jos 5 jun 2019, In: Nederlands Tijdschrift voor Geneeskunde. 163
Sarin Jaakko K, Nykänen Olli, Tiitu Virpi, Mancini Irina A D, Brommer Harold, Visser Jetze, Malda Jos, van Weeren P René, Afara Isaac O, Töyräs Juha 6 mei 2019, In: Annals of Biomedical Engineering. 47 , p. 1815-1826 12 p.
Lim Khoon S, Klotz BJ, Lindberg Gabriella C J, Melchels Ferry P W, Hooper Gary J, Malda Jos, Gawlitta Debby, Woodfield Tim B F 26 apr 2019, In: Macromolecular Bioscience. 19 14 p.
Piluso Susanna, Li Yang, Abinzano Florencia, Levato Riccardo, Moreira Teixeira Liliana, Karperien Marcel, Leijten Jeroen, van Weeren René, Malda Jos 16 apr 2019, In: Trends in biotechnology. 37 , p. 1063-1077 15 p.