dr. S. (Stefano) Mandija

dr. S. (Stefano) Mandija

Assistant Professor
dr. S. (Stefano) Mandija
  • Computational Imaging

Research Programs




Stefano is currently employed as assistant professor at the radiotherapy department of the University Medical Center Utrecht (The Netherlands). His research topics range from fundamental and methodological research to clinical development of quantitative MRI methods and MRI biomarkers for diagnostic and radiotherapy treatment response prediction and monitoring. In particular, he works on the characterization of tissue electrical properties for radiotherapy treatments efficacy assessment using MRI (NWO recipient VENI grant 2020), MRI-guided cardiac radio-ablation using stereotactic radiotherapy ( consortium), MRI-based guidance of spinal cord stimulation (RESTORE and Prep2GO consortia), and he also supports the development and translation of quantitative MRI methods in clinical settings (MR-STAT).


Stefano was born in Camposampiero, Padua (Italy) in September 1988. He was educated as a bioengineer at the University of Padua, 2007-2013. Afterwards, he moved to The Netherlands where he received his Ph.D. in the field of non-invasive characterization of tissue electrical properties with MRI at the University Medical Center Utrecht (The Netherlands) in 2018. Subsequently, he was offered a Post-Doc position at the Radiology and Radiotherapy departments of the University Medical Center Utrecht. Because of his passion for MRI and his positive attitude, which makes him looking at research challenges as new opportunities to expand his knowledge and to establish new collaborations, he also recently started investigating MRI-based guidance of cardiac ablation using stereotactic radiotherapy at the radiotherapy department of the University Medical Center Utrecht within the European STOPSTORM consortium.

Fellowship and Awards

NWO VENI Grant (2020): MR-based measurements of ‘Tissue ElectroMagnetic Properties in radiation Oncology (TEMPO)’: A predictive tool for early-stage assessment of radiotherapy treatments

Junior Fellow of the International Society for Magnetic Resonance in Medicine, ISMRM (2020)

Trainee Educational Stipend of the International Society for Magnetic Resonance in Medicine, ISMRM (2014, 2015, 2016)

Research Output (49)

MiPhDUO:microwave imaging via physics-informed deep unrolled optimization

Zumbo Sabrina, Mandija Stefano, Isernia Tommaso, Bevacqua Martina T. Apr 2024, In: Inverse Problems. 40

Stereotactic Arrhythmia Radioablation (STAR):Assessment of cardiac and respiratory heart motion in ventricular tachycardia patients - A consortium review

Stevens Raoul R F, Hazelaar Colien, Fast Martin F, Mandija Stefano, Grehn Melanie, Cvek Jakub, Knybel Lukas, Dvorak Pavel, Pruvot Etienne, Verhoeff Joost, Blanck Oliver, van Elmpt Wouter 4 Aug 2023, In: Radiotherapy & Oncology. 188

Real-time myocardial landmark tracking for MRI-guided cardiac radio-ablation using Gaussian Processes

Huttinga Niek Ricardo Ferdinand, Akdag Osman, Fast Martin F, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Van den Berg Cornelis A T, Sbrizzi Alessandro, Mandija Stefano 20 Jun 2023, In: Physics in medicine and biology. 68 14 p.

Synthetic MRI with Magnetic Resonance Spin TomogrAphy in Time-Domain (MR-STAT):Results from a Prospective Cross-Sectional Clinical Trial

Kleinloog Jordi P D, Mandija Stefano, D'Agata Federico, Liu Hongyan, van der Heide Oscar, Koktas Beyza, Dankbaar Jan Willem, Keil Vera C, Vonken Evert-Jan, Jacobs Sarah M, van den Berg Cornelis A T, Hendrikse Jeroen, van der Kolk Anja G, Sbrizzi Alessandro May 2023, In: Journal of Magnetic Resonance Imaging. 57 , p. 1451-1461 11 p.

STereotactic Arrhythmia Radioablation (STAR):the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium ( and review of current patterns of STAR practice in Europe

Grehn Melanie, Mandija Stefano, Miszczyk Marcin, Krug David, Tomasik Bartłomiej, Stickney Kristine E, Alcantara Pino, Alongi Filippo, Anselmino Matteo, Aranda Ricardo Salgado, Balgobind Brian V, Boda-Heggemann Judit, Boldt Leif-Hendrik, Bottoni Nicola, Cvek Jakub, Elicin Olgun, De Ferrari Gaetano Maria, Hassink Rutger J, Hazelaar Colien, Hindricks Gerhard, Hurkmans Coen, Iotti Cinzia, Jadczyk Tomasz, Jiravsky Otakar, Jumeau Raphaël, Buus Kristiansen Steen, Levis Mario, López Manuel Algara, Martí-Almor Julio, Mehrhof Felix, Møller Ditte Sloth, Molon Giulio, Ouss Alexandre, Peichl Petr, Plasek Jiri, Postema Pieter G, Quesada Aurelio, Reichlin Tobias, Rordorf Roberto, Rudic Boris, Saguner Ardan M, Ter Bekke Rachel M A, Torrecilla José López, Troost Esther G C, Vitolo Viviana, Andratschke Nicolaus, Zeppenfeld Katja, Blamek Slawomir, Fast Martin, de Panfilis Ludovica, Blanck Oliver, Pruvot Etienne, Verhoeff Joost J C 6 Mar 2023, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 25 , p. 1284-1295 12 p.

Walking with the ISMRM in the footprints of our MR history

Mandija Stefano, Ma Chao, Bai Ruiliang, Feng Li, Giganti Francesco, Ianus Andrada, Lee Hong-Hsi, Li Fei, Welton Thomas, Calamante Fernando Mar 2023, In: Magnetic Resonance in Medicine. 89 , p. 883-885 3 p.

Data-driven electrical conductivity brain imaging using 3 T MRI

Jung Kyu Jin, Mandija Stefano, Cui Chuanjiang, Kim Jun Hyeong, Al-masni Mohammed A., Meerbothe Thierry G., Park Mina, van den Berg Cornelis A.T., Kim Dong Hyun 2023, In: Human Brain Mapping. 44 , p. 4986-5001 16 p.

A database for MR-based electrical properties tomography with in silico brain data—ADEPT

Meerbothe T. G., Meliado E. F., Stijnman P. R.S., van den Berg C. A.T., Mandija S. 2023, In: Magnetic Resonance in Medicine. 91 , p. 1190-1199 10 p.

A Framework for Assessing the Effect of Cardiac and Respiratory Motion for Stereotactic Arrhythmia Radioablation Using a Digital Phantom With a 17-Segment Model:A Consortium Study

Stevens Raoul R F, Hazelaar Colien, Bogowicz Marta, Ter Bekke Rachel M A, Volders Paul G A, Verhoeven Karolien, de Ruysscher Dirk, Verhoeff Joost J C, Fast Martin F, Mandija Stefano, Cvek Jakub, Knybel Lukas, Dvorak Pavel, Blanck Oliver, van Elmpt Wouter 2023, In: International Journal of Radiation Oncology Biology Physics. 118 , p. 533-542 10 p.

Unrolled Microwave Imaging via Physics-assisted Deep Learning

Zumbo Sabrina, Mandija Stefano, Van Den Berg Cornelis A.T., Bevacqua Martina T., Isernia Tommaso 2023, p. 7-9 3 p.

All research output

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