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prof. dr. E.E.S. Nieuwenhuis

Full Professor

  • Gastroenterology & Hepatology research 1
  • Onderzoek

Research Output (121)

AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Wiggers Caroline R M, Baak Mirna L, Sonneveld Edwin, Nieuwenhuis Edward E S, Bartels Marije, Creyghton Menno P 10 sep 2019, In: Cell Reports. 28 , p. 2866-2877.e5

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

Govers Anita M A P, Wiggers Caroline R M, van Boxtel Ruben, Mokry Michal, Nieuwenhuis Edward E S, Creyghton Menno P, Bartels Marije, Coffer Paul J aug 2019, In: HemaSphere. 3

Motor function impairment is an early sign of CLN3 disease

Kuper Willemijn F.E., Van Alfen Claudia, Van Eck Linda, Huijgen Barbara C.H., Nieuwenhuis Edward E.S., Van Brussel Marco, Van Hasselt Peter M. 16 jul 2019, In: Neurology. 93 , p. e293-e297

Integrated analysis of transcriptional regulation in PLN R14del cardiomyopathy

Pei J., Harakalova M., Nagyova E., Gho J. M. I. H., Sepehrkhouy S., van Dinter J., van Mil A., Buijsrogge M. P., de Jonge N., Huibers M. M., Nieuwenhuis E. E. S., den Ruijter H. M., Pasterkamp G., Doevendans P. A., Hajjar R., Mercola M., Sluijter J. P. G., de Weger R. A., Cheng C., Vink A., Mokry M., Asselbergs F. W. jul 2019, In: European Journal of Human Genetics. 27 , p. 790-791

Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

Schreurs Renée R C E, Baumdick Martin E, Sagebiel Adrian F, Kaufmann Max, Mokry Michal, Klarenbeek Paul L, Schaltenberg Nicola, Steinert Fenja L, van Rijn Jorik M, Drewniak Agata, The Sarah-May M L, Bakx Roel, Derikx Joep P M, de Vries Niek, Corpeleijn Willemijn E, Pals Steven T, Gagliani Nicola, Friese Manuel A, Middendorp Sabine, Nieuwenhuis Edward E S, Reinshagen Konrad, Geijtenbeek Teunis B H, van Goudoever Johannes B, Bunders Madeleine J 19 feb 2019, In: Immunity. 50 , p. 462-476.e1-e8

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

Vervoort Stephin J, de Jong Olivier G, Roukens M Guy, Frederiks Cynthia L, Vermeulen Jeroen F, Lourenço Ana Rita, Bella Laura, Vidakovic Ana Tufegdzic, Sandoval José L, Moelans Cathy, van Amersfoort Miranda, Dallman Margaret J, Bruna Alejandra, Caldas Carlos, Nieuwenhuis Edward, van der Wall Elsken, Derksen Patrick, van Diest Paul, Verhaar Marianne C, Lam Eric W-F, Mokry Michal, Coffer Paul J 3 dec 2018, In: eLife. 7

Megakaryocyte lineage development is controlled by modulation of protein acetylation

Bartels Marije, Govers Anita, Polak Roel, Vervoort Stephin, Van Boxtel Ruben, Pals Cornelieke, Bierings Marc, Van Solinge Wouter, Egberts Toine, Nieuwenhuis Edward, Mokry Michal, Coffer Paul James 26 apr 2018, In: PLoS ONE. 13

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency

van Rijn Jorik M., Ardy Rico Chandra, Kuloğlu Zarife, Härter Bettina, van Haaften-Visser Désirée Y., van der Doef Hubert P.J., van Hoesel Marliek, Kansu Aydan, van Vugt Anke H.M., Thian Marini, Kokke Freddy T.M., Krolo Ana, Başaran Meryem Keçeli, Kaya Neslihan Gurcan, Aksu Aysel Ünlüsoy, Dalgıç Buket, Ozcay Figen, Baris Zeren, Kain Renate, Stigter Edwin C.A., Lichtenbelt Klaske D., Massink Maarten P.G., Duran Karen J., Verheij Joke B.G.M., Lugtenberg Dorien, Nikkels Peter G.J., Brouwer Henricus G.F., Verkade Henkjan J., Scheenstra René, Spee Bart, Nieuwenhuis Edward E.S., Coffer Paul J., Janecke Andreas R., van Haaften Gijs, Houwen Roderick H.J., Müller Thomas, Middendorp Sabine, Boztug Kaan 28 mrt 2018, In: Gastroenterology. 155 , p. 130-143.e15

Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease

Schneeberger Kerstin, Roth Sabrina, Nieuwenhuis Edward E. S., Middendorp Sabine feb 2018, In: Disease Models & Mechanisms. 11 12 p.

Chromatin Conformation Links Distal Target Genes to CKD Loci

Brandt Maarten M., Meddens Claartje A., Louzao-Martinez Laura, Van Den Dungen Noortje A.M., Lansu Nico R., Nieuwenhuis Edward E.S., Duncker Dirk J., Verhaar Marianne C., Joles Jaap A., Mokry Michal, Cheng Caroline 1 nov 2017, In: Journal of the American Society of Nephrology. 29 , p. 462-476 15 p.