dr. M. (Monique) Nijhuis

Associate Professor

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Research Output (117)

Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in all common circulating HIV subtypes and recombinant forms

Bosman Kobus J., Wensing Annemarie M. J., Pijning Aster E., van Snippenberg Wilco J., van Ham Petra M., de Jong Dorien M. C., Hoepelman Andy I. M., Nijhuis Monique 14 sep 2018, In: Journal of the International AIDS Society [E]. 21

The antiretroviral CCR5-inhibitor maraviroc effectively reverses HIV latency by phosphorylation of Nf-kappa B

Symons J., vanLelyveld S. F. L., deSpiegelaere W., Wensing A. M. J., Zerbato J. M., vanHam P. M., Drylewicz J., Middel A., Hoepelman A. I. M., Cameron P. U., Lu H. K., Dantanarayana A. I., Borghans J. A. M., Vandekerckhove L., Lewin S. R., Tesselaar K., Nijhuis M. jul 2018, In: Journal of the International AIDS Society [E]. 21 , p. 29-30

Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance

Fun Axel, Leitner Thomas, Vandekerckhove Linos, Däumer Martin, Thielen Alexander, Buchholz Bernd, Hoepelman Andy I.M., Gisolf Elizabeth H., Schipper Pauline J., Wensing Annemarie M.J., Nijhuis Monique 5 jan 2018, In: Retrovirology. 15 13 p.

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

Lebbink Robert Jan, de Jong Dorien C M, Wolters Femke, Kruse Elisabeth M, van Ham Petra M, Wiertz Emmanuel J H J, Nijhuis Monique 8 feb 2017, In: Scientific Reports. 7

HIV protease inhibitor resistance

Wensing Annemarie M.J., Fun Axel, Nijhuis Monique 1 jan 2017, p. 567-602 36 p.

High rates of transmission of drug-resistant HIV in Aruba resulting in reduced susceptibility to the WHO recommended first-line regimen in nearly half of newly diagnosed HIV-infected patients

Hofstra L. Marije, Rivas Elena Sánchez, Nijhuis Monique, Bank Leonie E.A., Wilkinson Eduan, Kelly Karina, Mudrikova Tania, Schuurman Rob, De Oliveira Tulio, De Kort Jaclyn, Wensing Annemarie M.J. 2017, In: Clinical Infectious Diseases. 64 , p. 1092-1097 6 p.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

van Diemen Ferdy R., Kruse Elisabeth M., Hooykaas Marjolein J G, Bruggeling Carlijn E., Schürch Anita C., van Ham Petra M., Imhof Saskia M., Nijhuis Monique, Wiertz Emmanuel J H J, Lebbink Robert Jan 1 jun 2016, In: PLoS Pathogens. 12

The presence of protective cytotoxic T lymphocytes does not correlate with shorter lifespans of productively infected cells in HIV-1 infection

Spits Hilde B, Mudrikova Tania, Schellens Ingrid M M, Wensing Annemarie M J, Prins Jan M, Feuth Thijs, Spierings Erik, Nijhuis Monique, van Baarle Debbie, Borghans José A M 2 jan 2016, In: AIDS. 30 , p. 9-17 9 p.

Clinical outcome of maraviroc-containing therapy in heavily pre-treated HIV-1-infected patients

Van Lelyveld S. F L, Symons J., Van Ham P., Connell B. J., Nijhuis M., Wensing A. M J, Hoepelman A. I M 1 jan 2016, In: International Journal of Antimicrobial Agents. 47 , p. 84-90 7 p.

Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir

Bosman K. J., Nijhuis M., van Ham P. M., Wensing A. M. J., Vervisch K., Vandekerckhove L., De Spiegelaere W. 9 sep 2015, In: Scientific Reports. 5 9 p.

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