dr. K. Oude Rengerink

dr. K. Oude Rengerink

Assistant Professor
dr. K. Oude Rengerink
  • Department of Epidemiology



Katrien Oude Rengerink works at the Julius Center, at the subdepartment of Clinical Trial Methodology, focusing on implementing and developing novel methodology for clinical trials. Next to that she is detached to the Medicines Evaluation Board / College ter Beoordeling van de Geneesmiddelen as methodology assesor. She is member of the Institutional Review Board of the department of Pharmacoepidemiology and Pharmacotherapy. She is member of the committeee Proefpersonenwerving of the Dutch Clinical Research Foundation.

After studying Biomedical Sciences, with a master in Epidemiology at Radboud University Nijmegen, she obtained her PhD on her thesis ‘Embedding trials in evidence-based clinical practice’ at the Academic Medical Center in Amsterdam, focused on improving recruitment of patients in clinical trials and the integration of EBM teaching in clinical practice.

During and after obtaining her PhD she worked as a methodologist for the Consortium for Studies in Womens’ Health ( and the department of Obstetrics and Gynaecology at the Academic Medical Center, Amsterdam. She was involved in the design, conduct, analysis and reporting of multiple multicenter trials in Obstetrics and Gynaecology, mostly focused on induction of labour and urinary incontinence treatment.
From 2015-2016 she worked as a
ssistant professor on Work Package 3 of the Get Real project, focused on methodological and operational challenges in pragmatic trial design. (


Research Output (76)

A narrative review of estimands in drug development and regulatory evaluation:old wine in new barrels?

Mitroiu M, Oude Rengerink K, Teerenstra S, Pétavy F, Roes K C B 23 jul 2020, In: Trials. 21

Inhibitor development in previously untreated patients with severe haemophilia:A comparison of included patients and outcomes between a clinical study and a registry-based study

Jonker Carla J, Oude Rengerink Katrien, Hoes Arno W, Mol Peter G M, van den Berg H Marijke 6 jul 2020, In: Haemophilia. 26 , p. 809-816 8 p.

Rivaroxaban was found to be noninferior to warfarin in routine clinical care:A retrospective noninferiority cohort replication study

Althunian Turki A, de Boer Anthonius, Groenwold Rolf H H, Rengerink Katrien O, Souverein Patrick C, Klungel Olaf H 14 jun 2020, In: Pharmacoepidemiology and Drug Safety. 29 , p. 1263-1272 10 p.

Rethinking the intention-to-treat principle:one size does not fit all

Oude Rengerink K, Mitroiu M, Teerenstra S, Pétavy F, Roes K C B 4 mei 2020, In: Journal of Clinical Epidemiology. 125 , p. 198-200 3 p.

The (cost) effectiveness of procedural sedation and analgesia versus general anaesthesia for hysteroscopic myomectomy, a multicentre randomised controlled trial:PROSECCO trial, a study protocol

van der Meulen Julia F, Bongers Marlies Y, Coppus Sjors F P J, Bosmans Judith E, Maessen José M C, Oude Rengerink Katrien, Overdijk Lucilla E, Radder Celine M, van der Voet Lucet F, Smeets Nicol A C, van Vliet Huib A A M, Hehenkamp Wouter J K, Manger Arentje P, Spaans Wilbert A, Bakkum Erica A, Horrée Nicole, Briët Justine M, van der Steeg Jan Willem, Kok Helen S 22 mrt 2019, In: BMC Women's Health. 19 , p. 46

Balloon catheter for induction of labor in women with one previous cesarean and an unfavorable cervix

Huisman Claartje M A, Ten Eikelder Mieke L G, Mast Kelly, Oude Rengerink Katrien, Jozwiak Marta, van Dunné Frédérique, Duvekot Johannes J, van Eyck Jim, Gaugler-Senden Ingrid, de Groot Christianne J M, Franssen Maureen T M, van Gemund Nicolette, Langenveld Josje, de Leeuw Jan Willem, Oude Lohuis Eefje J, Oudijk Martijn A, Papatsonis Dimitri, van Pampus Mariëlle, Porath Martina, Rombout-de Weerd Sabina, van Roosmalen Jos J, van der Salm Paulien C M, Scheepers Hubertina C J, Sikkema Marko J, Sporken Jan, Stigter Rob H, van Wijngaarden Wim J, Woiski Mallory, Mol Ben Willem J, Bloemenkamp Kitty W M, 5 feb 2019, In: Acta Obstetricia et Gynecologica Scandinavica. 98 , p. 920-928 9 p.

Systematic review showed that stepped wedge cluster randomized trials often did not reach their planned sample size

Eichner Felizitas A, Groenwold Rolf Hh, Grobbee Diederick E, Rengerink Katrien Oude 17 nov 2018, In: Journal of Clinical Epidemiology. 107 , p. 89-100 12 p.

Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe:methodological uncertainties

Pontes Caridad, Fontanet Juan Manuel, Vives Roser, Sancho Aranzazu, Gómez-Valent Mònica, Ríos José, Morros Rosa, Martinalbo Jorge, Posch Martin, Koch Armin, Roes Kit, Rengerink Katrien Oude, Torrent-Farnell Josep, Torres Ferran 15 nov 2018, In: Orphanet Journal of Rare Diseases. 13

Applicability and added value of novel methods to improve drug development in rare diseases

Mitroiu Marian, Rengerink Katrien Oude, Pontes Caridad, Sancho Aranzazu, Vives Roser, Pesiou Stella, Fontanet Juan Manuel, Torres Ferran, Nikolakopoulos Stavros, Pateras Konstantinos, Rosenkranz Gerd, Posch Martin, Urach Susanne, Ristl Robin, Koch Armin, Loukia Spineli, van der Lee Johanna H, Roes Kit C B 12 nov 2018, In: Orphanet Journal of Rare Diseases. 13 , p. 200

Pharmacological pain relief and fear of childbirth in low risk women; secondary analysis of the RAVEL study

Logtenberg Sabine L M, Verhoeven Corine J, Rengerink Katrien Oude, Sluijs Anne-Marie, Freeman Liv M, Schellevis François G, Mol Ben Willem 25 aug 2018, In: BMC Pregnancy and Childbirth [E]. 18

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht





Practical maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet