prof. dr. G. (Gerard) Pasterkamp
Full Professor
- Department of Clinical Chemistry and Haematology
Contact
Biography
Gerard Pasterkamp, MD, is professor Experimental Cardiology and scientific medical manager of the division LAB. UMC Utrecht. His research interests are in the field of cardiovascular biology and more specifically innovation in biomarkers. His research interests are in the field of cardiovascular biology and innovation in biomarkers and drug targets. The research group houses the largest atherosclerotic plaque biobank worldwide: Athero Express including >4000 patients. This biobank has generated new insights into determinants of plaque destabilisation. The laboratory also invests in the excavation of genetic determinants of atherosclerotic plaque characteristics. He coordinates national and EU based consortia with the aim to unravel biomarkers and mechanisms of atherosclerotic disease. His translational profile is noted in the private public consortia he is involved in. He is supervising three public private grants that have been rewarded with the aim to develop novel biomarkers and imaging technology to detect cardiac ischemia and endothelial dysfunction. In 2018 he obtained a LeDucq grant together with Prof G Owens (Virginia University) on the role of smooth muscle cell plasticity in the atherosclerotic plaque.
Side Activities
Editorial scientific board ATVB, Cardiovascular research, Atherosclerosis, Eur J Cardiovascular Pharmacology
Board member of Dutch Atherosclerosis Society
Review board LS7 EU-ERC advanced grants
Research Output (560)
Validation of randomized controlled trial-derived models for the prediction of postintervention outcomes in chronic limb-threatening ischemia
Wijnand Joep G J, van Koeverden Ian D, Teraa Martin, Spreen Marlon I, Mali Willem P T M, van Overhagen Hans, Pasterkamp Gerard, de Borst Gert J, Conte Michael S, Gremmels Hendrik, Verhaar Marianne C 1 mrt 2020, In: Journal of Vascular Surgery. 71 , p. 869-879 11 p.
Automated calcium scores collected during myocardial perfusion imaging improve identification of obstructive coronary artery disease
Dekker Mirthe, Waissi Farahnaz, Bank Ingrid E.M., Lessmann Nikolas, Išgum Ivana, Velthuis Birgitta K., Scholtens Asbjørn M., Leenders Geert E., Pasterkamp Gerard, de Kleijn Dominique P.V., Timmers Leo, Mosterd Arend 1 feb 2020, In: IJC Heart and Vasculature. 26 6 p.
The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases
Bosch Lena, de Haan Judith J., Seijkens Tom T.P., van Tiel Claudia M., Brans Maike A.D., Pasterkamp Gerard, Lutgens Esther, de Jager Saskia C.A. 1 feb 2020, In: International Journal of Cardiology. 300 , p. 220-220 1 p.
Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac:the Aneurysm-Express Biobank Cohort
van Laarhoven Constance J.H.C.M., van Setten Jessica, van Herwaarden Joost A., Pasterkamp Gerard, de Kleijn Dominique P.V., de Borst Gert J., van der Laan Sander W. 27 dec 2019, In: Scientific Reports. 9
Magnetic Resonance Imaging Identified Brain Ischaemia in Symptomatic Patients Undergoing Carotid Endarterectomy Is Related to Histologically Apparent Intraplaque Haemorrhage
Rots Marjolijn L., Timmerman Nathalie, de Kleijn Dominique P.V., Pasterkamp Gerard, Brown Martin M., Bonati Leo H., de Borst Gert J. 1 dec 2019, In: European Journal of Vascular and Endovascular Surgery. 58 , p. 796-804 9 p.
A Pro-Inflammatory Biomarker-Profile Predicts Amputation-Free Survival in Patients with Severe Limb Ischemia
Gremmels Hendrik, Teraa Martin, de Jager Saskia C.A., Pasterkamp Gerard, de Borst Gert J., Verhaar Marianne C. 1 dec 2019, In: Scientific Reports. 9
A head-to-head comparison of conjugation methods for VHHs:Random maleimide-thiol coupling versus controlled click chemistry
van Moorsel Marc V.A., Urbanus Rolf T., Verhoef S., Koekman C. A., Vink Maurice, Vermonden T., Maas Coen, Pasterkamp Gerard, Schiffelers Raymond M. 1 dec 2019, In: International Journal of Pharmaceutics: X. 1
Associations of autozygosity with a broad range of human phenotypes
Clark David W et al. 1 dec 2019, In: Nature Communications. 10
Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia
Hartman Robin J.G., Korporaal Suzanne J.A., Mokry Michal, de Jager Saskia C.A., Meeuwsen John A.L., van der Laan Sander W., Lansu Nico R., Zoet Gerbrand A., Pasterkamp Gerard, Urbanus Rolf T., Hoefer Imo E., Franx Arie, Velthuis Birgitta K., van Rijn Bas B., den Ruijter Hester M., 1 dec 2019, In: Atherosclerosis. 291 , p. 114-121 8 p.
Effect of vagus nerve stimulation on tissue damage and function loss in a mouse myocardial ischemia-reperfusion model
Nederhoff M. G.J., Fransen D. E., Verlinde S. A.M.W., Brans M. A.D., Pasterkamp G., Bleys R. L.A.W. 1 nov 2019, In: Autonomic Neuroscience: Basic and Clinical. 221