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dr. V. (Victor) Peperzak Assistant Professor

  • Laboratory for Translational Immunology (LTI)

V. Peperzak

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Research Programs

Research Output (17)

Dexamethasone synergizes with MCL-1 inhibition in multiple myeloma through suppression of S6 phosphorylation

Spaan Ingrid, Timmerman Laura, Kimman Thoman, Slomp Anne, Cuenca Marta, Minnema Monique, Raymakers Reinier, Peperzak Victor okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E110-E110

MCL-1 Inhibition Is Highly Effective Against Multiple Myeloma Cells from Poor Prognosis Patients

Slomp Anne, Moesbergen Laura M., Halkes Constantijn J. M., Sonneveld Pieter, Minnema Monique C., Peperzak Victor 29 nov 2018, In: Blood. 132 , p. 1916

From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells

van Nieuwenhuijzen Niels, Spaan Ingrid, Raymakers Reinier, Peperzak Victor 15 mei 2018, In: Cancer Research. 78 , p. 2449-2456 8 p.

Wnt signaling in multiple myeloma:a central player in disease with therapeutic potential

Spaan Ingrid, Raymakers Reinier A, van de Stolpe Anja, Peperzak Victor 2018, In: Journal of hematology & oncology. 11

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Vikström Ingela B, Slomp Anne, Carrington Emma M, Moesbergen Laura M, Chang Catherine, Kelly Gemma L, Glaser Stefan P, Jansen J H Marco, Leusen Jeanette H W, Strasser Andreas, Huang David C S, Lew Andrew M, Peperzak Victor, Tarlinton David M 2016, In: Cell death & disease. 7

The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation

Peperzak Victor, Veraar EA, Keller AM, Xiao Y, Borst J 1 dec 2010, In: Journal of Immunology.

Mcl-1 is essential for germinal center formation and B cell memory

Vikstrom I, Carotta S, Luthje K, Peperzak Victor, Jost PJ, Glaser S, Busslinger M, Bouillet P, Strasser A, Nutt SL, Tarlinton DM 19 nov 2010, In: Science.

The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells

Zwart W, Peperzak Victor, de Vries E, Keller AM, van der Horst G, Veraar EA, Geumann U, Janssen H, Janssen L, Naik SH, Neefjes J, Borst J 1 nov 2010, In: Journal of Cell Science.

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells

Xiao Y, Peperzak Victor, van Rijn L, Borst J, de Bruijn JD jul 2010, In: Journal of Tissue Engineering and Regenerative Medicine.

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

Peperzak Victor, Xiao Y, Veraar EA, Borst J jan 2010, In: Journal of Clinical Investigation.

All Research Output (17)
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