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dr. V. (Victor) Peperzak

Assistant Professor

  • Laboratory for Translational Immunology (LTI)

Research Output (20)

Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting

Slomp Anne, Moesbergen Laura M, Gong Jia-Nan, Cuenca Marta, von dem Borne Peter A, Sonneveld Pieter, Huang David C S, Minnema Monique C, Peperzak Victor 23 dec 2019, In: Blood Advances. 3 , p. 4202-4214 13 p.

Multiple myeloma with amplification of chromosome 1q is highly sensitive to MCL-1 targeting

Slomp Anne, Moesbergen Laura, Gong Jia-nan, Cuenca Marta, Borne Peter von dem, Sonneveld Pieter, Huang David, Minnema Monique, Peperzak Victor okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E49-E50

A Highly Reproducible 3D Culture Approach for Functional Drug Testing on Primary Multiple Myeloma Cells.

Peperzak Victor, Cuenca Marta, Moesbergen Laura, van Nieuwenhuijzen Niels, Slomp Anne, Minnema Monique okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E97-E97

Dexamethasone synergizes with MCL-1 inhibition in multiple myeloma through suppression of S6 phosphorylation

Spaan Ingrid, Timmerman Laura, Kimman Thoman, Slomp Anne, Cuenca Marta, Minnema Monique, Raymakers Reinier, Peperzak Victor okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E110-E110

MCL-1 Inhibition Is Highly Effective Against Multiple Myeloma Cells from Poor Prognosis Patients

Slomp Anne, Moesbergen Laura M., Halkes Constantijn J. M., Sonneveld Pieter, Minnema Monique C., Peperzak Victor 29 nov 2018, In: Blood. 132 , p. 1916

From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells

van Nieuwenhuijzen Niels, Spaan Ingrid, Raymakers Reinier, Peperzak Victor 15 mei 2018, In: Cancer Research. 78 , p. 2449-2456 8 p.

Wnt signaling in multiple myeloma:a central player in disease with therapeutic potential

Spaan Ingrid, Raymakers Reinier A, van de Stolpe Anja, Peperzak Victor 2018, In: Journal of hematology & oncology. 11

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Vikström Ingela B, Slomp Anne, Carrington Emma M, Moesbergen Laura M, Chang Catherine, Kelly Gemma L, Glaser Stefan P, Jansen J H Marco, Leusen Jeanette H W, Strasser Andreas, Huang David C S, Lew Andrew M, Peperzak Victor, Tarlinton David M 2016, In: Cell death & disease. 7

The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation

Peperzak Victor, Veraar EA, Keller AM, Xiao Y, Borst J 1 dec 2010, In: Journal of Immunology.

Mcl-1 is essential for germinal center formation and B cell memory

Vikstrom I, Carotta S, Luthje K, Peperzak Victor, Jost PJ, Glaser S, Busslinger M, Bouillet P, Strasser A, Nutt SL, Tarlinton DM 19 nov 2010, In: Science.