prof. dr. B.W. (Bas W.) Raaymakers

Full Professor
prof. dr. B.W. (Bas W.) Raaymakers
  • Experimental Clinical Physics Radiotherapy

Research Programs

Strategic Program Cancer



Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.

Side Activities

Member of International Advisory Committee of Physics in Medicine and Biology



Fellowship and Awards

VENI grant in 2003, Technical feasibility of the MRI accelerator

Research Output (176)

Deep learning prediction of proton and photon dose distributions for paediatric abdominal tumours

Guerreiro F, Seravalli E, Janssens G O, Maduro J H, Knopf A C, Langendijk J A, Raaymakers B W, Kontaxis C mrt 2021, In: Radiotherapy & Oncology. 156 , p. 36-42 7 p.

DeepDose:a robust deep learning-based dose engine for abdominal tumours in a 1.5 T MRI radiotherapy system

Tsekas Georgios, Bol Gijsbert H, Raaymakers Bas W, Kontaxis Charis 5 feb 2021, In: Physics in medicine and biology. 66 , p. 065017

Quantitative investigation of dose accumulation errors from intra-fraction motion in MRgRT for prostate cancer

Bosma Lando, Zachiu Cornel, Ries Mario G, Denis de Senneville Baudouin, Raaymakers Bas W 26 jan 2021, In: Physics in medicine and biology. 66 , p. 065002

Impact of a vacuum cushion on intrafraction motion during online adaptive MR-guided SBRT for pelvic and para-aortic lymph node oligometastases

Werensteijn-Honingh Anita M, Jürgenliemk-Schulz Ina M, Gadellaa-Van Hooijdonk Christa G, Sikkes Gonda G, Vissers Nicole G P M, Winkel Dennis, Eppinga Wietse S C, Intven Martijn, Raaymakers Bas W, Kroon Petra S jan 2021, In: Radiotherapy & Oncology. 154 , p. 110-117 8 p.

Proof-of-concept delivery of intensity modulated arc therapy on the Elekta Unity 1.5 T MR-linac

Kontaxis Charis, Woodhead Peter L, Bol Gijsbert H, Lagendijk Jan J W, Raaymakers Bas W 23 dec 2020, In: Physics in medicine and biology. 66

Roadmap:proton therapy physics and biology

Paganetti Harald, Beltran Chris J, Both Stefan, Dong Lei, Flanz Jacob B, Furutani Keith M, Grassberger Clemens, Grosshans David R, Knopf Antje-Christin, Langendijk Johannes A, Nyström Håkan, Parodi Katia, Raaymakers Bas W, Richter Christian, Sawakuchi Gabriel O, Schippers Jacobus Maarten, Shaitelman Simona F, Teo Kevin, Unkelbach Jan, Wohlfahrt Patrick, Lomax Antony John 23 nov 2020, In: Physics in medicine and biology. 66

Deep learning-enabled MRI-only photon and proton therapy treatment planning for paediatric abdominal tumours

Florkow Mateusz C, Guerreiro Filipa, Zijlstra Frank, Seravalli Enrica, Janssens Geert O, Maduro John H, Knopf Antje C, Castelein René M, van Stralen Marijn, Raaymakers Bas W, Seevinck Peter R 7 okt 2020, In: Radiotherapy & Oncology. 153 , p. 220-227 8 p.

Prostate intrafraction motion during the preparation and delivery of MR-guided radiotherapy sessions on a 1.5T MR-Linac

de Muinck Keizer D. M., Kerkmeijer L. G.W., Willigenburg T., van Lier A. L.H.M.W., Hartogh M. D.den, van der Voort van Zyp J. R.N., de Groot-van Breugel E. N., Raaymakers B. W., Lagendijk J. J.W., de Boer J. C.J. okt 2020, In: Radiotherapy and Oncology. 151 , p. 88-94 7 p.

Dosimetric feasibility of hypofractionation for SBRT treatment of lymph node oligometastases on the 1.5T MR-linac

Winkel D, Werensteijn-Honingh A M, Eppinga W S C, Intven M P W, Hes J, Snoeren L M W, Visser S A, Bol G H, Raaymakers B W, Jürgenliemk-Schulz I M, Kroon P S 16 sep 2020, In: Radiotherapy & Oncology. 154 , p. 243-248 6 p.

Anatomically-adaptive multi-modal image registration for image-guided external-beam radiotherapy

Zachiu Cornel, Denis de Senneville Baudouin, Willigenburg Thomas, van der Voort van Zyp Jochem R N, de Boer J C J, Raaymakers Bas W, Ries Mario G 7 aug 2020, In: Physics in medicine and biology. 65 , p. 1-21

All research output

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