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prof. dr. B.W. (Bas W.) Raaymakers

prof. dr. B.W. (Bas W.) Raaymakers

Full Professor
prof. dr. B.W. (Bas W.) Raaymakers
  • Experimental Clinical Physics Radiotherapy

Research Programs

Strategic Program Cancer

Biography

Biography

Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.

Side Activities

 

Member of International Advisory Committee of Physics in Medicine and Biology (unpaid)

 

 

 

Fellowship and Awards

VENI grant in 2003, Technical feasibility of the MRI accelerator

Research Output (210)

ESTRO Breur lecture 2022:Real-time MRI-guided radiotherapy: The next generation standard?

Lagendijk Jan J W, Raaymakers Bas W, Intven Martijn P W, van der Voort van Zyp Jochem R N Nov 2022, In: Radiotherapy & Oncology. 176 , p. 244-248 5 p.

Dosimetric evaluation of off-axis fields and angular transmission for the 1.5 T MR-linac

van den Dobbelsteen M., Hackett S. L., de Vries J. H.W., van Asselen B., Oolbekkink S., Woodings S. J., Raaymakers B. W. 21 Oct 2022, In: Physics in medicine and biology. 67

Robust deep learning-based forward dose calculations for VMAT on the 1.5T MR-Linac

Tsekas Georgios, Bol Gijsbert H, Raaymakers Bas W 5 Oct 2022, In: Physics in medicine and biology. 67 , p. 1-8

Clinical application of a sub-fractionation workflow for intrafraction re-planning during prostate radiotherapy treatment on a 1.5 Tesla MR-Linac:A practical method to mitigate intrafraction motion

Willigenburg Thomas, Zachiu Cornel, Bol Gijsbert H, de Groot-van Beugel Eline N, Lagendijk Jan J W, van der Voort van Zyp Jochem R N, Raaymakers Bas W, de Boer Johannes C J 14 Sep 2022, In: Radiotherapy & Oncology. 176 , p. 25-30 6 p.

Dosimetric impact of intrafraction motion under abdominal compression during MR-guided SBRT for (Peri-) pancreatic tumors

Grimbergen Guus, Eijkelenkamp Hidde, Heerkens Hanne D, Raaymakers Bas W, Intven Martijn P W, Meijer Gert J 30 Aug 2022, In: Physics in medicine and biology. 67 , p. 1-9

First experimental demonstration of VMAT combined with MLC tracking for single and multi fraction lung SBRT on an MR-linac

Uijtewaal Prescilla, Borman Pim T.S., Woodhead Peter L., Kontaxis Charis, Hackett Sara L., Verhoeff Joost, Raaymakers Bas W., Fast Martin F. 8 Jul 2022, In: Radiotherapy & Oncology. 174 , p. 149-157 9 p.

Impact of magnetic resonance-guided versus conventional radiotherapy workflows on organ at risk doses in stereotactic body radiotherapy for lymph node oligometastases

Werensteijn-Honingh Anita M, Kroon Petra S, Winkel Dennis, van Gaal J Carlijn, Hes Jochem, Snoeren Louk M W, Timmer Jaleesa K, Mout Christiaan C P, Bol Gijsbert H, Kotte Alexis N, Eppinga Wietse S C, Intven Martijn, Raaymakers Bas W, Jürgenliemk-Schulz Ina M Jul 2022, In: Physics and Imaging in Radiation Oncology. 23 , p. 66-73 8 p.

A hybrid 2D/4D-MRI methodology using simultaneous multi-slice imaging for radiotherapy guidance

Keijnemans Katrinus, Borman Pim T S, Uijtewaal Prescilla, Woodhead Peter L, Raaymakers Bas W, Fast Martin F 13 Jun 2022, In: Medical Physics. 49 , p. 6068-6081 14 p.

Accumulated bladder wall dose is correlated with patient-reported acute urinary toxicity in prostate cancer patients treated with stereotactic, daily adaptive MR-guided radiotherapy

Willigenburg Thomas, van der Velden Joanne M., Zachiu Cornel, Teunissen Frederik R., Lagendijk Jan J.W., Raaymakers Bas W., de Boer Johannes C.J., van der Voort van Zyp Jochem R.N. Jun 2022, In: Radiotherapy and Oncology. 171 , p. 182-188 7 p.

Robust Multi-Site Deep Learning-Based Dose Predictions for Volumetric Modulated Arc Therapy Using the MR-Linac

Tsekas G., Bol G., Raaymakers B. Jun 2022, In: Medical Physics. 49 , p. E344-E345

All research output

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