prof. dr. B.W. (Bas W.) Raaymakers
Full Professor
- Experimental Clinical Physics Radiotherapy
Contact
Biography
Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.
Side Activities
Member of International Advisory Committee of Physics in Medicine and Biology
Fellowship and Awards
VENI grant in 2003, Technical feasibility of the MRI accelerator
Research Output (165)
Delivered dose quantification in prostate radiotherapy using online 3D cine imaging and treatment log files on a combined 1.5T magnetic resonance imaging and linear accelerator system
Kontaxis Charis, de Muinck Keizer Daan M., Kerkmeijer Linda G.W., Willigenburg Thomas, den Hartogh Mariska D., van der Voort van Zyp Jochem R.N., de Groot-van Breugel Eline N., Hes Jochem, Raaymakers Bas W., Lagendijk Jan J.W., de Boer Hans C.J. jul 2020, In: Physics and Imaging in Radiation Oncology. 15 , p. 23-29 7 p.
Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment
Winkel Dennis, Bol Gijsbert H., Werensteijn-Honingh Anita M., Intven Martijn P.W., Eppinga Wietse S.C., Hes Jochem, Snoeren Louk M.W., Sikkes Gonda G., Gadellaa-van Hooijdonk Christa G.M., Raaymakers Bas W., Jürgenliemk-Schulz Ina M., Kroon Petra S. 1 mei 2020, In: Radiotherapy and Oncology. 146 , p. 118-125 8 p.
DeepDose:Towards a fast dose calculation engine for radiation therapy using deep learning
Kontaxis C, Bol G H, Lagendijk J J W, Raaymakers B W 8 apr 2020, In: Physics in medicine and biology. 65 10 p.
Dosimetric impact of soft-tissue based intrafraction motion from 3D cine-MR in prostate SBRT
de Muinck Keizer D M, Kontaxis C, Kerkmeijer L G W, van der Voort van Zyp J R N, van den Berg C A T, Raaymakers B W, Lagendijk J J W, de Boer J C J 17 jan 2020, In: Physics in Medicine and Biology. 65 10 p.
Biomechanical quality assurance criteria for deformable image registration algorithms used in radiotherapy guidance
Zachiu Cornel, de Senneville Baudouin Denis, Raaymakers Bas W, Ries Mario 10 jan 2020, In: Physics in Medicine and Biology. 65 19 p.
Fast contour propagation for MR-guided prostate radiotherapy using convolutional neural networks
Eppenhof K A J, Maspero M, Savenije M H F, de Boer J C J, van der Voort van Zyp J R N, Raaymakers B W, Raaijmakers A J E, Veta M, van den Berg C A T, Pluim J P W 26 dec 2019, In: Medical Physics. 47 , p. 1238-1248 11 p.
Soft-tissue prostate intrafraction motion tracking in 3D cine-MR for MR-guided radiotherapy
de Muinck Keizer Daan M, Kerkmeijer Linda G W, Maspero Matteo, Andreychenko Anna, van der Voort van Zyp Jochem R N, Van den Berg Cornelis A T, Raaymakers Bas W, Lagendijk Jan J W, de Boer J C J 5 dec 2019, In: Physics in Medicine and Biology. 64 , p. 235008 12 p.
The transformation of radiation oncology using real-time magnetic resonance guidance:A review
Hall William A., Paulson Eric S., van der Heide Uulke A., Fuller Clifton D., Raaymakers B. W., Lagendijk Jan J.W., Li X. Allen, Jaffray David A., Dawson Laura A., Erickson Beth, Verheij Marcel, Harrington Kevin J., Sahgal Arjun, Lee Percy, Parikh Parag J., Bassetti Michael F., Robinson Clifford G., Minsky Bruce D., Choudhury Ananya, Tersteeg Robert J.H.A., Schultz Christopher J., 1 nov 2019, In: European Journal of Cancer. 122 , p. 42-52 11 p.
ReconSocket:A low-latency raw data streaming interface for real-time MRI-guided radiotherapy
Borman P. T.S., Raaymakers B. W., Glitzner M. 17 sep 2019, In: Physics in medicine and biology. 64 , p. 185008
Evaluating the benefit of PBS vs. VMAT dose distributions in terms of dosimetric sparing and robustness against inter-fraction anatomical changes for pediatric abdominal tumors
Guerreiro Filipa, Zachiu Cornel, Seravalli Enrica, Ribeiro Cássia O, Janssens Geert O, Ries Mario, de Senneville Baudouin Denis, Maduro John H, Brouwer Charlotte L, Korevaar Erik W, Knopf Antje C, Raaymakers Bas W sep 2019, In: Radiotherapy & Oncology. 138 , p. 158-165 8 p.