prof. dr. F.H. Rutten

prof. dr. F.H. Rutten

Full Professor
prof. dr. F.H. Rutten
  • Department of General Practice
  • Julius Center Research Program Cardiovascular Epidemiology

Research Programs

Circulatory Health



I hold a position as professor in general practice. I lead a research group focusing on the management of cardiovascular disease in primary care, from early detection of disease and risk-stratification to risk-based treatment.

My teaching activities cover being involved in educational programs at the bachelor (CRU) and master (Summa) level at the medical school, and also being involved in the specialty training and post-graduate training courses of general practitioners. I am a member of the steering committee of the Dutch 'kaderopleiding hart- en vaatziekten' for general practitioners and actively participate in its teaching program.

My research group has contributed to improving the diagnosis of heart failure and deep venous thrombosis in the primary care setting, and our studies have been used as building blocks for diagnostic algorithms recommended by the (inter)national guidelines regarding these diseases. By showing that unrecognized heart failure is common in patients with chronic obstructive pulmonary disease (COPD) and also in type 2 diabetes, our work has helped revolutionize clinical practice. I contributed to the development of guidelines on heart failure, atrial fibrillation, left ventricular hypertrophy and Non-ST elevated Acute Coronary Syndrome for the European Society of Cardiology, and also to the educational practice guideline documents on heart failure and atrial fibrillation for the European Primary Care Cardiovascular Society. Over the years I have been actively involved in working groups of the Heart Failure Association of the European Society of Cardiology, and was instrumental in translating the interactive website '' to Dutch, making it understandable for patients and their carers.

Within the UMC Utrecht, I am member of the coreteam of the theme ('speerpunt') Circulatory Health.

I managed to acquire ample funding for the clinical research activities of our research group. In 2017 I became the successful recipient of a research grant of Cardiovascular Research Netherlands (CVON), with myself being the main applicant of a consortium that will focus on early diagnosis of heart failure, atrial fibrillation and coronary artery disease in patients who participate in primary care disease management programs for COPD or type 2 diabetes. The aim is to facilitate early treatment and improve prognosis by preventing acute cardiovascular events such as acute heart failure, stroke and acute coronary syndrome.

I am coordinator of the Research Programme Cardiovascular Health of the Julius Center for Health Sciences and Primary Care of the UMC Utrecht. In addition I am member of the leadership team of the Julius Center, chair of research of the department of general practice, and board member of the management team of the department of General Practice within the Julius Center.

I collaborate with other departments of the Julius Center (epidemiology, public health and nursing sciences) and the clinical departments of Cardiology, Vascular Surgery, Vascular Medicine and renal disease, as well as with the department of imaging.

Side Activities

2018- Member of the Advisory Board of the European Primary Care Cardiovascular Society

2017- Board Member of the research consortium of Dutch General Practitioners and of the 'Interfacultair Overleg Huisartsgeneeskunde, Research (IOH-R)'

2015-2022 Board Member of the Scientific Advisory Committee of the Netherlands Heart Foundation

2014-2018 Editorial Board Member of Family Practice

2012- Board Member and supervisor of General Practioners' 'Kaderopleiding hart- en vaatziekten'

1992-2018 General Practitioner, part-time, in Rhenen 

2018- Free lance General Practitioner no more than one day a week

2021- Editorial Board Member Frontiers of cardiovascular epidemiology

2019- Vice chair of the ZonMw research programme 'Early detection of disease'

Fellowship and Awards

2014   Utrecht General Practitioner of the year award

2017-  Fellow of the European Society of Cardiology

2018   The Dr. Carel Bakx award for achievements in cardiovascular research in primary care

Research Output (290)

Electrocardiographic Features of Left Ventricular Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction:A Systematic Review

Van Ommen Anne-Mar, Kessler Elise Laura, Valstar Gideon, Onland-Moret N Charlotte, Cramer Maarten Jan, Rutten Frans, Coronel Ruben, Den Ruijter Hester 17 dec 2021, In: Frontiers in cardiovascular medicine. 8 , p. 1-11

Cardiovasculaire combinatiepillen

Bots Michiel L., Rutten Frans H., Westerink Jan 15 okt 2021, In: Nederlands Tijdschrift voor Geneeskunde. 165

Nu thuismeting van zuurstofsaturatie ineens reguliere huisartsenzorg lijkt te zijn…

Zwart Dorien, Venekamp Roderick, Smit Karin, Geersing Geert Jan, Kalkman Cor, Rutten Frans 2021, In: Huisarts en Wetenschap. 64 , p. 43-44 2 p.

Real-life impact of clinical prediction rules for venous thromboembolism in primary care:a cross-sectional cohort study

van Maanen Rosanne, Kingma Annelieke E C, Oudega Ruud, Rutten Frans H, Moons Karel, Geersing Geert-Jan 28 dec 2020, In: BMJ Open. 10 , p. 1-13

Is the time of calling helpful for differentiating transient ischaemic attack and stroke from mimics in primary care out-of-hours services?:A cross-sectional study

Erkelens Daphne Ca, Zwart Dorien L, van der Meer Gerben H, Wouters Loes Tcm, De Groot Esther, Damoiseaux Roger Amj, Hoes Arno W, Rutten Frans H 17 dec 2020, In: BMJ Open. 10 , p. 1-10

Missed Acute Coronary Syndrome During Telephone Triage at Out-of-Hours Primary Care Lessons From A Case-Control Study

Erkelens Daphne C , Rutten Frans H, Wouters Loes, Kirkels Harmke, Poldervaart Judith, de Groot Esther, Damoiseaux Roger, Hoes Arno W., Zwart Dorien 14 dec 2020, In: Journal of Patient Safety.

Accuracy of telephone triage in patients suspected of transient ischaemic attack or stroke:a cross-sectional study

Erkelens Daphne C, Rutten Frans H, Wouters Loes T, Dolmans L Servaas, de Groot Esther, Damoiseaux Roger A, Zwart Dorien L 5 dec 2020, In: BMC Family Practice. 21 , p. 1-10

Training general practitioners to improve evidence-based drug treatment of patients with heart failure:a cluster randomised controlled trial

Valk M J M, Hoes A W, Mosterd A, Landman M A, Zuithoff N P A, Broekhuizen B D L, Rutten F H 30 sep 2020, In: Netherlands Heart Journal. 28 , p. 604-612 9 p.

Proactive screening for symptoms:A simple method to improve early detection of unrecognized cardiovascular disease in primary care. Results from the Lifelines Cohort Study

Zwartkruis Victor W., Groenewegen Amy, Rutten Frans H., Hollander Monika, Hoes Arno W., van der Ende M. Yldau, van der Harst Pim, Cramer Maarten Jan, van der Schouw Yvonne T., Koffijberg Hendrik, Rienstra Michiel, de Boer Rudolf A. sep 2020, In: Preventive Medicine. 138

Design and rationale of DUTCH-AF:a prospective nationwide registry programme and observational study on long-term oral antithrombotic treatment in patients with atrial fibrillation

Chu Gordon, Seelig Jaap, Trinks-Roerdink Emmy M., van Alem Anouk P., Alings Marco, van den Bemt Bart, Boersma Lucas Va, Brouwer Marc A., Cannegieter Suzanne C., Ten Cate Hugo, Kirchhof Charles Jhj, Crijns Harry Jgm, van Dijk Ewoud J., Elvan Arif, van Gelder Isabelle C., de Groot Joris R., den Hartog Frank R., de Jong Jonas Ssg, de Jong Sylvie, Klok Frederikus A., Lenderink Timo, Luermans Justin G., Meeder Joan G., Pisters Ron, Polak Peter, Rienstra Michiel, Smeets Frans, Tahapary Giovanni Jm, Theunissen Luc, Tieleman Robert G., Trines Serge A., van der Voort Pepijn, Geersing Geert Jan, Rutten Frans H., Hemels Martin Ew, Huisman Menno V. 24 aug 2020, In: BMJ Open. 10 , p. 1-9

All research output

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