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dr. A.F. (Floriaan) Schmidt

dr. A.F. (Floriaan) Schmidt

Assistant Professor
  • Onderzoek Precision medicine

Research Output (35)

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

Schmidt Amand F., Hunt Nicholas B., Gordillo-Marañón Maria, Charoen Pimphen, Drenos Fotios, Kivimaki Mika, Lawlor Deborah A., Giambartolomei Claudia, Papacosta Olia, Chaturvedi Nishi, Bis Joshua C., O’Donnell Christopher J., Wannamethee Goya, Wong Andrew, Price Jackie F., Hughes Alun D., Gaunt Tom R., Franceschini Nora, Mook-Kanamori Dennis O., Zwierzyna Magdalena, Sofat Reecha, Hingorani Aroon D., Finan Chris dec 2021, In: Nature Communications. 12

No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease:A Mendelian Randomization Analysis

Mensah-Kane Josephine, Schmidt Amand F., Hingorani Aroon D., Finan Chris, Chen Yutang, van Duijvenboden Stefan, Orini Michele, Lambiase Pier D., Tinker Andrew, Marouli Eirini, Munroe Patricia B., Ramírez Julia 18 feb 2021, In: Frontiers in Genetics. 12

Risk Factors and Prevalence of Dilated Cardiomyopathy in Sub-Saharan Africa:Protocol for a Systematic Review

Fundikira Lulu Said, Chillo Pilly, van Laake Linda W, Mutagaywa Reuben Kato, Schmidt Amand Floriaan, Kamuhabwa Appolinary, Kwesigabo Gideon, Asselbergs Folkert W 21 jan 2021, In: JMIR Research Protocols. 10

Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population

Joshi Roshni, Wannamethee Goya, Engmann Jorgen, Gaunt Tom, Lawlor Deborah A., Price Jackie, Papacosta Olia, Shah Tina, Tillin Therese, Whincup Peter, Chaturvedi Nishi, Kivimaki Mika, Kuh Diana, Kumari Meena, Hughes Alun D., Casas Juan P., Humphries Steve E., Hingorani Aroon D., Schmidt A. Floriaan, jan 2021, In: Annals of Clinical Biochemistry. 58 , p. 47-53 7 p.

Mendelian randomization for studying the effects of perturbing drug targets

Gill Dipender, Georgakis Marios K., Walker Venexia M., Schmidt A. Floriaan, Gkatzionis Apostolos, Freitag Daniel F., Finan Chris, Hingorani Aroon D., Howson Joanna M.M., Burgess Stephen, Swerdlow Daniel I., Davey Smith George, Holmes Michael V., Dichgans Martin, Scott Robert A., Zheng Jie, Psaty Bruce M., Davies Neil M. 2021, In: Wellcome Open Research. 6

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease

Schmidt Amand F., Carter John Paul L., Pearce Lucy S., Wilkins John T., Overington John P., Hingorani Aroon D., Casas J. P. 20 okt 2020, In: The Cochrane database of systematic reviews. 10 , p. 1-87

Association between 8 P-glycoprotein (MDR1/ABCB1) gene polymorphisms and antipsychotic drug-induced hyperprolactinaemia

Geers Lisanne M., Pozhidaev Ivan V., Ivanova Svetlana A., Freidin Maxim B., Schmidt Amand F., Cohen Dan, Boiko Anastasiia S., Paderina Diana Z., Fedorenko Olga Yu, Semke Arkadiy V., Bokhan Nikolay A., Wilffert Bob, Kosterink Jos G.W., Touw Daan J., Loonen Anton J.M. 1 sep 2020, In: British Journal of Clinical Pharmacology. 86 , p. 1827-1835 9 p.

Genetic drug target validation using Mendelian randomisation

Schmidt Amand F, Finan Chris, Gordillo-Marañón Maria, Asselbergs Folkert W, Freitag Daniel F, Patel Riyaz S, Tyl Benoît, Chopade Sandesh, Faraway Rupert, Zwierzyna Magdalena, Hingorani Aroon D 26 jun 2020, In: Nature Communications. 11 , p. 1-12

Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases

Howe Laurence J, Dudbridge Frank, Schmidt Amand F, Finan Chris, Denaxas Spiros, Asselbergs Folkert W, Hingorani Aroon D, Patel Riyaz S 28 mei 2020, In: Human molecular genetics. 29 , p. 1388-1395 8 p.

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