Back

dr. ir. G.C.M. (Trudy) Straetemans

dr. ir. G.C.M. (Trudy) Straetemans

Assistant Professor
  • Laboratory for Translational Immunology (LTI)
  • Department of Medical Oncology

Research Programs

Strategic Program Cancer

Research Output (13)

αβ T-cell graft depletion for allogeneic HSCT in adults with hematological malignancies

De Witte Moniek A., Janssen Anke, Nijssen Klaartje, Karaiskaki Froso, Swanenberg Luuk, van Rhenen Anna, Admiraal Rick, van der Wagen Lotte, Minnema Monique C., Petersen Eefke, Raymakers Reinier A.P., Westinga Kasper, Straetemans Trudy, Halkes Constantijn J.M., Boelens Jaap Jan, Kuball Jurgen 12 jan 2021, In: Blood Advances. 5 , p. 240-249 10 p.

gamma 9 delta 2T cell diversity and the receptor interface with tumor cells

Vyborova Anna, Beringer Dennis X, Fasci Domenico, Karaiskaki Froso, van Diest Eline, Kramer Lovro, de Haas Aram, Sanders Jasper, Janssen Anke, Straetemans Trudy, Olive Daniel, Leusen Jeanette Hw, Boutin Lola, Nedellec Steven, Schwartz Samantha L, Wester Michael J, Lidke Keith A, Scotet Emmanuel, Lidke Diane, Heck Albert Jr, Sebestyen Zsolt, Kuball Jurgen 2 jun 2020, In: Journal of Clinical Investigation. 130 , p. 4637-4651 15 p.

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

Johanna Inez, Hernández-López Patricia, Heijhuurs Sabine, Bongiovanni Laura, de Bruin Alain, Beringer Dennis, van Dooremalen Sanne, Shultz Leonard D, Ishikawa Fumihiko, Sebestyen Zsolt, Straetemans Trudy, Kuball Jürgen 5 feb 2020, In: Journal of Leukocyte Biology. 107 , p. 1069-1079 11 p.

gamma delta T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity

Janssen Anke, Villacorta Hidalgo José, Beringer Dennis X, van Dooremalen Sanne F.J., Fernando Febilla, van Diest Eline, Terrizzi Antonela R, Bronsert Peter, Kock Sylvia, Schmitt-Graeff Annette, Werner Martin, Heise Kerstin, Follo Marie, Straetemans Trudy, Sebestyen Zsolt, Chudakov Dmitriy M, Kasatskaya Sofya A, Frenkel Felix E, Ravens Sarina, Spierings Eric, Prinz Immo, Küppers Ralf, Malkovsky Miroslav, Fisch Paul, Kuball Jurgen 4 feb 2020, In: Cancer Immunology Research. 8 , p. 530-543 14 p.

TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product

Straetemans Trudy, Janssen Anke, Jansen Koen, Doorn Ruud, Aarts Tineke, van Muyden Anna D D, Simonis Marieke, Bergboer Judith, de Witte Moniek, Sebestyen Zsolt, Kuball Jurgen 14 dec 2019, In: Molecular Therapy. 28 , p. 561-571 11 p.

Identification of a tumor-specific allo-HLA-restricted γδTCR

Kierkels G J J, Scheper W, Meringa A D, Johanna I, Beringer D X, Janssen A, Schiffler M, Aarts-Riemens T, Kramer L, Straetemans T, Heijhuurs S, Leusen J H W, San José E, Fuchs K, Griffioen M, Falkenburg J H, Bongiovanni L, de Bruin A, Vargas-Diaz D, Altelaar M, Heck A J R, Shultz L D, Ishikawa F, Nishimura M I, Sebestyén Z, Kuball J 8 okt 2019, In: Blood Advances. 3 , p. 2870-2882 13 p.

Evaluating in vivo efficacy - Toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

Johanna Inez, Straetemans Trudy, Heijhuurs Sabine, Aarts-Riemens Tineke, Norell Håkan, Bongiovanni Laura, De Bruin Alain, Sebestyen Zsolt, Kuball Jürgen 12 mrt 2019, In: Journal for ImmunoTherapy of Cancer. 7

GMP-grade manufacturing of T cells engineered to express a defined γδTCR

Straetemans Trudy, Kierkels Guido J.J., Doorn Ruud, Jansen Koen, Heijhuurs Sabine, dos Santos Joao M., van Muyden Anna D.D., Vie Henri, Clemenceau Béatrice, Raymakers Reinier, de Witte Moniek, Sebestyén Zsolt, Kuball Jürgen 30 mei 2018, In: Frontiers in Immunology [E]. 9

Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Braham Maaike V.J., Minnema Monique C., Aarts Tineke, Sebestyen Zsolt, Straetemans Trudy, Vyborova Anna, Kuball Jurgen, Öner F. Cumhur, Robin Catherine, Alblas Jacqueline 12 feb 2018, In: OncoImmunology. 7

The next step toward GMP-grade production of engineered immune cells

Kierkels Guido J J, Straetemans Trudy, de Witte Moniek A, Kuball Jürgen feb 2016, In: OncoImmunology. 5

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht

Contact

Emergency?

Directions

Appointments

Practical

umcutrecht.nl maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet