dr. R.T. (Rolf) Urbanus

Associate Professor
dr. R.T. (Rolf) Urbanus
  • Hematology/Van Creveldclinic

Research Programs

Circulatory Health



Rolf Urbanus obtained his PhD at the department of Clinical Chemistry and Haematology of the UMC Utrecht on a dissertation entitled “Arterial Thrombosis in the Antiphospholipid Syndrome” in 2008. Following a period as a Postdoctoral Fellow, he became an Assistant Professor at the same department in 2011 to establish his own research line. When Rolf joined the Van Creveldkliniek in 2018, an existing fruitful collaboration was formalized and the Van Creveld laboratory for Thrombosis and Haemostasis was founded. Rolf’s current research focusses on the (patho)physiology of thrombosis and haemostasis, with an emphasis on rare thrombotic and hemorrhagic disorders. Special interests are the autoimmune disorder Antiphospholipid Syndrome (APS) and inherited platelet function defects.

Research Output (102)

Bleeding phenotype and diagnostic characterization of patients with congenital platelet defects

Blaauwgeers Maaike W., Kruip Marieke J.H.A., Beckers Erik A.M., Coppens Michiel, Eikenboom Jeroen, van Galen Karin P.M., Tamminga Rienk Y.J., Urbanus Rolf T., Schutgens Roger E.G. 1 okt 2020, In: American Journal of Hematology. 95 , p. 1142-1147 6 p.

Fasciola hepatica Serine Protease Inhibitor Family (Serpins):Purposely crafted for regulating host proteases

De Marco Verissimo Carolina, Jewhurst Heather L, Tikhonova Irina G, Urbanus Rolf T, Maule Aaron G, Dalton John P, Cwiklinski Krystyna 6 aug 2020, In: PLoS Neglected Tropical Diseases. 14 31 p.

Sex differences in flow cytometry-based platelet reactivity in stable outpatients suspected of myocardial ischemia

Waissi Farahnaz, Dekker Mirthe, Bank Ingrid E M, Korporaal Suzanne J A, Urbanus Rolf T, de Borst Gert J, Pasterkamp Gerard, Scholtens Asbjorn M, Grobbee Diederick E, Mosterd Arend, de Kleijn Dominique P V, Timmers Leo jul 2020, In: Research and practice in thrombosis and haemostasis. 4 , p. 879-885 7 p.

Schistosoma mansoni infection affects the proteome and lipidome of circulating extracellular vesicles in the host

Bexkens Michiel L, van Gestel Renske A, van Breukelen Bas, Urbanus Rolf T, Brouwers Jos F, Nieuwland Rienk, Tielens Aloysius G M, van Hellemond Jaap J 27 jun 2020, In: Molecular and Biochemical Parasitology. 238 7 p.

Diagnostiek bij een vermoedelijke stollingsstoornis

van Vulpen Lize F.D., Wichers Iris M., Urbanus Rolf T., van Galen Karin P.M. 1 jan 2020, In: Nederlands Tijdschrift voor Geneeskunde. 164 7 p.

Congenital platelet disorders and health status-related quality of life

Blaauwgeers Maaike W, Kruip Marieke J H A, Beckers Erik A M, Coppens Michiel, Eikenboom Jeroen, van Galen Karin P M, Tamminga Rienk Y J, Urbanus Rolf T, Schutgens Roger E G, jan 2020, In: Research and practice in thrombosis and haemostasis. 4 , p. 100-105 6 p.

Flow cytometric mepacrine fluorescence can be used for the exclusion of platelet dense granule deficiency

van Asten Ivar, Blaauwgeers Maaike, Granneman Lianne, Heijnen Harry F G, Kruip Marieke J H A, Beckers Erik A M, Coppens Michiel, Eikenboom Jeroen, Tamminga Rienk Y J, Pasterkamp Gerard, Huisman Albert, van Galen Karin P M, Korporaal Suzanne J A, Schutgens Roger E G, Urbanus Rolf T 9 dec 2019, In: Journal of thrombosis and haemostasis : JTH. 18 , p. 706-713 8 p.

Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia

Hartman Robin J.G., Korporaal Suzanne J.A., Mokry Michal, de Jager Saskia C.A., Meeuwsen John A.L., van der Laan Sander W., Lansu Nico R., Zoet Gerbrand A., Pasterkamp Gerard, Urbanus Rolf T., Hoefer Imo E., Franx Arie, Velthuis Birgitta K., van Rijn Bas B., den Ruijter Hester M., 1 dec 2019, In: Atherosclerosis. 291 , p. 114-121 8 p.

A head-to-head comparison of conjugation methods for VHHs:Random maleimide-thiol coupling versus controlled click chemistry

van Moorsel Marc V.A., Urbanus Rolf T., Verhoef S., Koekman C. A., Vink Maurice, Vermonden T., Maas Coen, Pasterkamp Gerard, Schiffelers Raymond M. 1 dec 2019, In: International Journal of Pharmaceutics: X. 1

Heparin Forms Polymers with Cell-free DNA Which Elongate Under Shear in Flowing Blood

de Vries Joost C, Barendrecht Arjan D, Clark Chantal C, Urbanus Rolf T, Boross Peter, de Maat Steven, Maas Coen 1 dec 2019, In: Scientific Reports. 9

All research output

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