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prof. dr. M. (Marry) van den Heuvel-Eibrink

Full Professor

  • Speerpunt

Research Programs

Biography

MD, PhD Professor translational Pediatric Oncology.

Since 2015, working in the Princess Maxima Center for Pediatric Oncology, and responsible for the now established centralized care and translational research program for all children with renal tumors and on the identification of (genetic) determinants direct and late toxicity.
Since 2016 Medical director of the late effects clinics in the Princess Maxima Center for Pediatric Oncology, Utrecht, the Netherlands.

Research
Decidated to translational research in pediatric oncology, with a special focus on myeloid malignancies, renal tumors and the (genetic) variation of early and late toxicity of childhood cancer.

Side Activities

  • (Inter)national Boards/Committees/Memberships

    • Dutch Pediatric Association (NVK), since 1991 (member)

    • Dutch Society of Oncology, NVvO, 1993- onwards (member)

    • Dutch Hematology Association (NVvH), since 1995 (member)

    • International Society of Pediatric Oncology (SIOP), since 1996 (member)

    • European Hematology Association (EHA), since 1998 (member)

    • American Society of Hematology (ASH), since 1998 (member)

    • EWOG-MDS group 1999-onwards (member)

    • Dutch Childhood Oncology Group (DCOG) Renal tumor committee 2000 – 2008 (member), 2008 – onwards (chair)

    • I-BFM-AML committee, 2000-onwards (member)

    • DCOG MDS protocol committee, 2003-onwards (chair)

    • Scientific Board of EWOG MDS, 2005 – 2011 (member), 2011 – 2017 (chair)

    • Steering committee DCOG-LATER committee, 2006 – onwards (member)

    • Advisory Board of the International JMML Foundation, 2007- onwards (member)

    • DCOG Disease Committee Bone Marrow Failure and MDS, 2008-onwards (member)

    • SIOP Scientific Programs Advisory Committee(SPAC), 2008-onwards (contributor)

    • DCOG Steering committee for Late effects, 2009- onwards (member)

    • Steering CIE SIOP-RTSG, since 2009 (member)

    • Advisory Board of the DCOG (Raad van Toezicht), 2014 – onwards (member)

    • Organizing committee of annual meeting of the European Hematology Association(EHA), SPC 2014, 2015, 2016 (member)

    • International Steering Committee for renal tumors (SIOP RTSG), 2014- onwards (member and co-chair)

    • Scientific EHA symposium board (SPC) 2014-2017 (member)

    • SIOP scientific CIE, October 2017-2020 (member)

    • Member SIOP-e (member)

    • PanCare (member)

     

    Editorial Board

    • European J of Cancer

    • Pediatric Blood and cancer

    • Journal of Pediatric Endocrinology

     

    Reviewer

    • Pediatric Blood and Cancer

    • Haematologica

    • J of Pediatric Biochemistry

    • Clinical Cancer Research

    • Leukaemia Research

    • J Ped Hem Onc

    • Clin Cancer Research

    • Leukaemia

    • British J of Hematology

    • J of supportive care in Cancer

    • European J of Endocrinology

    • Cancer

    • Am J of Blood

    • Eur J of Cancer

    • Lancet Oncology

    • BMC

    • JCO

    .

Research Output (102)

Paediatric metanephric tumours:a clinicopathological and molecular characterisation

de Jel Dominique V C, Hol Janna A, Ooms Ariadne H A G, de Krijger Ronald R, Jongmans Marjolijn C J, Littooij Annemieke S, Drost Jarno, van Grotel Martine, van den Heuvel-Eibrink Marry M jun 2020, In: Critical Reviews in Oncology/Hematology. 150 7 p.

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

Calandrini Camilla, Schutgens Frans, Oka Rurika, Margaritis Thanasis, Candelli Tito, Mathijsen Luka, Ammerlaan Carola, van Ineveld Ravian L., Derakhshan Sepide, de Haan Sanne, Dolman Emmy, Lijnzaad Philip, Custers Lars, Begthel Harry, Kerstens Hindrik H.D., Visser Lindy L., Rookmaaker Maarten, Verhaar Marianne, Tytgat Godelieve A.M., Kemmeren Patrick, de Krijger Ronald R., Al-Saadi Reem, Pritchard-Jones Kathy, Kool Marcel, Rios Anne C., van den Heuvel-Eibrink Marry M., Molenaar Jan J., van Boxtel Ruben, Holstege Frank C.P., Clevers Hans, Drost Jarno 11 mrt 2020, In: Nature Communications. 11

Is radiotherapy required in first-line treatment of stage I diffuse anaplastic Wilms tumor? A report of SIOP-RTSG, AIEOP, JWiTS, and UKCCSG

Fajardo Raquel Dávila, van den Heuvel-Eibrink Marry M., van Tinteren Harm, Spreafico Filippo, Acha Thomas, Bergeron Christophe, de Camargo Beatriz, Oldenburger Foppe, Rübe Christian, Oue Takaharu, Vokuhl Christian, de Krijger Ronald R., Vujanic Gordan, Sebire Neil, Coulomb-L'Hermine Aurore, Collini Paola, Gandola Lorenza, Pritchard-Jones Kathy, Graf Norbert, Janssens Geert O., van Grotel Martine 1 feb 2020, In: Pediatric Blood and Cancer. 67

Diagnostic tools for early detection of cardiac dysfunction in childhood cancer survivors:Methodological aspects of the Dutch late effects after childhood cancer (LATER) cardiology study

Leerink Jan M., Feijen E. Lieke A.M., van der Pal Helena J.H., Kok Wouter E.M., Mavinkurve-Groothuis Annelies M.C., Kapusta Livia, Pinto Yigal M., Maas Angela H.E.M., Bellersen Louise, Teske Arco J., Ronckers Cécile M., Louwerens Marloes, van Dalen Elvira C., van Dulmen-den Broeder Eline, Batenburg Lilian, van der Heiden-van der Loo Margriet, van den Heuvel-Eibrink Marry M., van Leeuwen Flora E., de Vries Andrica C.H., Weijers Gert, de Korte Chris L., Loonen Jacqueline J., Neggers Sebastian J.C.M.M., Versluys A. B.Birgitta, Tissing Wim J.E., Kremer Leontien C.M., 1 jan 2020, In: American Heart Journal. 219 , p. 89-98 10 p.

Renal cell carcinoma in young FH mutation carriers:case series and review of the literature

Hol J A, Jongmans M C J, Littooij A S, de Krijger R R, Kuiper R P, van Harssel J J T, Mensenkamp A, Simons M, Tytgat G A M, van den Heuvel-Eibrink M M, van Grotel M 2 dec 2019, In: Familial Cancer. 19 , p. 55-63 9 p.

Fatigue in Children Post-Cancer Treatment and Other Long-Term Diseases

Nap-Van der Vlist M., Dalmeijer G., Grootenhuis M., van der Ent C., van den Heuvel-Eibrink M., Wulffraat N., Swart J., van Litsenburg R., van de Putte E., Nijhof S. dec 2019, In: Pediatric Blood & Cancer. 66 , p. S150-S151

MRI-guided definition of cerebrospinal fluid distribution around cranial and sacral nerves:implications for brain tumors and craniospinal irradiation

Wood Amber M, Lequin Maarten H, Philippens Marielle M, Seravalli Enrica, Plasschaert Sabine L, van den Heuvel-Eibrink Marry M, Janssens Geert O dec 2019, In: Acta Oncologica. 58 , p. 1740-1744 5 p.

Towards More Efficient Detection of Genetic Predisposition in Pediatric Renal Tumors: A Systematic Phenotypic Characterization

Hol J., Kuiper R. P., Koudijs M. J., Waanders E., Morgado L. M., van den Heuvel-Eibrink M. M., Jongmans M. C. J. dec 2019, In: Pediatric Blood & Cancer. 66 , p. S19-S19

Publisher Correction:The UMBRELLA SIOP–RTSG 2016 Wilms tumour pathology and molecular biology protocol (Nature Reviews Urology, (2018), 15, 11, (693-701), 10.1038/s41585-018-0100-3)

Vujanić Gordan M., Gessler Manfred, Ooms Ariadne H.A.G., Collini Paola, Coulomb-l’Hermine Aurore, D’Hooghe Ellen, de Krijger Ronald R., Perotti Daniela, Pritchard-Jones Kathy, Vokuhl Christian, van den Heuvel-Eibrink Marry M., Graf Norbert, 1 sep 2019, In: Nature Reviews Urology. 16 , p. 563-563 1 p.

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort

Teepen Jop C., Kremer Leontien C., van der Heiden-van der Loo Margriet, Tissing Wim J., van der Pal Helena J., van den Heuvel-Eibrink Marry M., Loonen Jacqueline J., Louwerens Marloes, Versluys Birgitta, van Dulmen-den Broeder Eline, Visser Otto, Maduro John H., van Leeuwen Flora E., Ronckers Cecile M., Aleman B. M.P., Caron H. N., Grootenhuis M. A., den Hartogh J. G., Hollema N., Neggers S. J.C.M.M., Postma A., de Ridder-Sluiter J. G., Rutgers E. J.T., 1 sep 2019, In: Cancer Causes and Control. 30 , p. 909-922 14 p.

All Research Output (102)