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dr. S.W. (Sander) van der Laan

Assistant Professor

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Research Output (60)

Monocyte-chemoattractant protein-1 levels in human atherosclerotic lesions associate with plaque vulnerability

Georgakis Marios K., van der Laan Sander W., Asare Yaw, Mekke Joost M., Haitjema Saskia, Schoneveld Arjan H., de Jager Saskia C.A., Nurmohamed Nick S., Kroon Jeffrey, Stroes Erik S.G., de Kleijn Dominique P.V., de Borst Gert J., Maegdefessel Lars, Soehnlein Oliver, Pasterkamp Gerard, Dichgans Martin 8 apr 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41 , p. 2038-2048 11 p.

The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease

Demandt J A F, Dubois L J, van Kuijk K, Zaťovičová M, Jin H, Parkkila S, van der Laan S W, Jelenska L, Mees B M E, Reutelingsperger C P M, Cleutjens K B J M, van der Kallen C J H, Schalkwijk C G, van Greevenbroek M M J, Biessen E A L, Pasterkamp G, Pastoreková S, Stehouwer C D A, Sluimer J C 11 jan 2021, In: Scientific Reports. 11 14 p.

Functional investigation of the coronary artery disease gene SVEP1

Winkler Michael J, Müller Philipp, Sharifi Amin M, Wobst Jana, Winter Hanna, Mokry Michal, Ma Lijiang, van der Laan Sander W, Pang Shichao, Miritsch Benedikt, Hinterdobler Julia, Werner Julia, Stiller Barbara, Güldener Ulrich, Webb Tom R, Asselbergs Folkert W, Björkegren Johan L M, Maegdefessel Lars, Schunkert Heribert, Sager Hendrik B, Kessler Thorsten dec 2020, In: Basic Research in Cardiology. 115 , p. 1-15

Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells

Aherrahrou Rédouane, Guo Liang, Nagraj Vijay Peter, Aguhob Aaron Andrew, Hinkle Jameson, Chen Lisa, Soh Joon Yuhl, Lue Dillon, Alencar Gabriel F, Boltjes Arjan, van der Laan Sander W, Farber Emily, Fuller Daniela, Anane-Wae Rita, Akingbesote Ngozi D, Manichaikul Ani W, Ma Lijiang, Kaikkonen Minna U, Björkegren Johan Lm, Onengut-Gumuscu Suna, Pasterkamp Gerard, Miller Clint L, Owens Gary K, Finn Aloke V, Navab Mohamad, Fogelman Alan M, Berliner Judith A, Civelek Mete 12 okt 2020, In: Circulation research. 127 , p. 1552-1565 14 p.

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Depuydt Marie Ac, Prange Koen Hm, Slenders Lotte, Örd Tiit, Elbersen Danny, Boltjes Arjan, de Jager Saskia Ca, Asselbergs Folkert W, de Borst Gert J, Aavik Einari, Lönnberg Tapio, Lutgens Esther, Glass Christopher K, den Ruijter Hester M, Kaikkonen Minna U, Bot Ilze, Slütter Bram, van der Laan Sander W, Yla-Herttuala Seppo, Mokry Michal, Kuiper Johan, de Winther Menno Pj, Pasterkamp Gerard 28 sep 2020, In: Circulation research. 127 , p. 1437-1455 19 p.

Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke

von Berg Joanna, van der Laan Sander W, McArdle Patrick F, Malik Rainer, Kittner Steven J, Mitchell Braxton D, Worrall Bradford B, de Ridder Jeroen, Pulit Sara L 11 feb 2020, In: European Journal of Human Genetics. 28 , p. 963-972 10 p.

Beyond GWAS in Atrial Fibrillation Genetics

van der Laan Sander W, Asselbergs Folkert W 31 jan 2020, In: Circulation research. 126 , p. 361-363 3 p.

PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling

Rykaczewska Urszula, Suur Bianca E, Röhl Samuel, Razuvaev Anton, Lengquist Mariette, Sabater-Lleal Maria, van der Laan Sander W, Miller Clint L, Wirka Robert C, Kronqvist Malin, Gonzalez Diez Maria, Vesterlund Mattias, Gillgren Peter, Odeberg Jacob, Lindeman Jan Hn, Veglia Fabrizio, Humphries Steve E, de Faire Ulf, Baldassarre Damiano, Tremoli Elena, Lehtiö Janne, Hansson Göran K, Paulsson-Berne Gabrielle, Pasterkamp Gerard, Quertermous Thomas, Hamsten Anders, Eriksson Per, Hedin Ulf, Matic Ljubica 2 jan 2020, In: Circulation research. 126 , p. 571-585 15 p.

Family history and polygenic risk of cardiovascular disease:Independent factors associated with secondary cardiovascular events in patients undergoing carotid endarterectomy

Timmerman Nathalie, de Kleijn Dominique P.V., de Borst Gert J., den Ruijter Hester M., Asselbergs Folkert W., Pasterkamp Gerard, Haitjema Saskia, van der Laan Sander W. 1 jan 2020, In: Atherosclerosis. 307 , p. 121-129 9 p.

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