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dr. J. (Jorg) van Loosdregt

dr. J. (Jorg) van Loosdregt

Associate Professor

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Research Output (33)

Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation

Mijnheer Gerdien, Lutter Lisanne, Mokry Michal, van der Wal Marlot, Scholman Rianne, Fleskens Veerle, Pandit Aridaman, Tao Weiyang, Wekking Mark, Vervoort Stephin, Roberts Ceri, Petrelli Alessandra, Peeters Janneke G C, Knijff Marthe, de Roock Sytze, Vastert Sebastiaan, Taams Leonie S, van Loosdregt Jorg, van Wijk Femke dec 2021, In: Nature Communications. 12 , p. 1-16

Tissue-Resident Memory T Cells in Chronic Inflammation-Local Cells with Systemic Effects?

Samat Anoushka Ashok Kumar, van der Geest Jolijn, Vastert Sebastiaan J, van Loosdregt Jorg, van Wijk Femke 16 feb 2021, In: Cells. 10 18 p.

COMPARTMENTALIZATION, PERSISTENCE AND CONSERVED SHARED MOTIFS OF DOMINANT (REGULATORY) T CELL CLONES IN AUTOIMMUNE INFLAMMATION

Mijnheer G., Servaas N., Lutter L., Leong J. Y., Spierings E., Chen P., Petrelli A., Vastert S., de Boer R., Albani S., van Loosdregt J., Pandit A., van Wijk F. 2021, In: Clinical and Experimental Rheumatology. 39 , p. 1153-1154

Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis:Results From a Five-Year Follow-Up Study

ter Haar Nienke M., van Dijkhuizen E. H.Pieter, Swart Joost F., van Royen-Kerkhof Annet, el Idrissi Ayman, Leek Arjen P., de Jager Wilco, de Groot Mark C.H., Haitjema Saskia, Holzinger Dirk, Foell Dirk, van Loosdregt Jorg, Wulffraat Nico M., de Roock Sytze, Vastert Sebastiaan J. 8 mrt 2019, In: Arthritis & Rheumatology. 71 , p. 1163-1173 11 p.

Restoring T cell tolerance, exploring the potential of histone deacetylase inhibitors for the treatment of juvenile idiopathic arthritis

Nijhuis Lotte, Peeters Janneke G.C., Vastert Sebastiaan J., Van Loosdregt Jorg 7 feb 2019, In: Frontiers in Immunology. 10

Molecular mechanisms of autophagic memory in pathogenic T cells in human arthritis

Kumar Pavanish, Yao Leong Jing, Saidin Suzan, Paleja Bhairav, van Loosdregt Jorg, Chua Camillus, Arkachaisri Thaschawee, Consolaro Alessandro, Gattorno Marco, Martini Alberto, Pischel Ken D., Williams Gary W., Lotz Martin, Albani Salvatore 1 nov 2018, In: Journal of Autoimmunity. 94 , p. 90-98 9 p.

The role of WNT signaling in mature T cells:T cell factor is coming home

Van Loosdregt Jorg, Coffer Paul J. 15 okt 2018, In: Journal of Immunology. 201 , p. 2193-2200 8 p.

Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method:A study protocol

Schoemaker Casper G., Armbrust Wineke, Swart Joost F., Vastert Sebastiaan J., Van Loosdregt Jorg, Verwoerd Anouk, Whiting Caroline, Cowan Katherine, Olsder Wendy, Versluis Els, Van Vliet Rens, Fernhout Marlous J., Bookelman Sanne L., Cappon Jeannette, Van Den Berg J. Merlijn, Schatorjé Ellen, Muller Petra C.E.Hissink, Kamphuis Sylvia, De Boer Joke, Lelieveld Otto T.H.M., Van Der Net Janjaap, Jongsma Karin R., Van Rensen Annemiek, Dedding Christine, Wulffraat Nico M. 15 sep 2018, In: Pediatric Rheumatology. 16

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

Peeters J. G.C., Picavet L. W., Coenen S. G.J.M., Mauthe M., Vervoort S. J., Mocholi E., de Heus C., Klumperman J., Vastert S. J., Reggiori F., Coffer P. J., Mokry M., van Loosdregt J. 28 aug 2018, In: Autophagy. 15 , p. 98-112 15 p.

ARTHRITIS IS NOT A PREREQUISITE DISEASE MANIFESTATION FOR THE DIAGNOSIS OF SYSTEMIC JIA: RESULTS OF A PROSPECTIVE COHORT TRIAL USING RIL-1RA AS FIRST LINE TREATMENT WITH LONG TERM FOLLOW-UP

Ter Haar N. M., Leek A., El Idrissi A., Swart J. F., van Loosdregt J., Wulffraat N., de Roock S., Vastert S. jun 2018, In: Annals of the Rheumatic Diseases. 77 , p. 1663-1663

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