dr. H.M. van Santen Associate Professor - medical
- Endocrinology patient care
Dr. HM van Santen moved her career in 2013 to Utrecht to support the Máxima initiative and to coordinate the endocrine care for children with cancer in the Princess Máxima Center.
She has co-authored > 50 publications on the endocrine effects of childhood cancer treatment, of which 27 as first or last author.
She is an associate professor and PI in the research program of Child Health, WKZ, UMCU and collaborates closely together with the Máxima Center for Pediatric Oncology . Internationally, she collaborates closely with the endocrine and late effects department of the St Jude’s Hospital (Dr W Chemaitilly, Dr M Hudson).
Her research program focusses on craniopharyngioma and thyroid cancer in childhood and on the endocrine effects of childhood cancer treatment, with special interest for the thyroid gland, pituitary gland and hypothalamus aiming to preserve an intact endocrine system in children with cancer enabling normal growth and development of the child during and after childhood cancer treatment.
She is chair of the Late Effects of Childhood Cancer International Guideline Harmonization Groups (IGHG) for thyroid and hypothalamic-pituitary disorders, and member of the IGHG working groups for male and female gonadal toxicity and preservation of fertility and metabolic syndrome. She is chair of the Dutch and the European Guideline for Thyroid cancer in children and the coordinator of the NFU/ ENDO-ERN expertise center Thyroid Tumors in Utrecht. She is member of the SKION craniopharyngioma working group, the SIOP supportive care group, the SIOP low grade glioma working group, the national consortium for Late effects of treatment for childhood thyroid carcinoma, the consortium of the Dexadagen-2 study, the Dutch Growth Hormone Advisory board and has a consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma.
2019 BKO qualification UMCU
2019 Chair of the European Task Force for Recommendations of Treatment of Thyroid nodules and Carcinoma in Childhood
2016 – now Deputy educator ( plaatsvervangend opleider) of the clinical fellow pediatric endocrinology in the Wilhelmina Children’s Hospital, UMCU
2018 - now member of working group supportive care Princess Maxima Center
2017 - now member of fertility working group Princess Maxima Center
2016 - now Co-chair of the IGHG for surveillance of hypothalamic-pituitary disorders in Childhood Cancer Survivors
2016 - now Participant/ member of the working group of the IGHG working group for preservation of fertility in male childhood cancer survivors (in progress)
2016 – now Participant / working group lead of the IGHG working group for preservation of fertility in female childhood cancer survivors (in progress)
2016 - now Participant/ member of the working group of the IGHG recommendation for surveillance of the metabolic syndrome in childhood cancer survivors (in progress)
2016 - now Co-chair of the Dutch Guideline for Treatment of Thyroid nodules and cancer in children (in progress)
2016 - now Participant of the SIOP supportive care group
2016 - now Participant of the SIOP low grade glioma working group
2016 - now Participant of the national consortium for Late effects of treatment for childhood thyroid carcinoma ( PI T Links, UMCG)
2016 - now Participant of the consortium of the Dexadagen-2 study
2015 - now Participant of the Dutch Growth Hormone Advisory board (SEK)
2015 - now Consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma(www.cyberpoli.nl)
2015 – now Participant of the SKION LATER Recommendations for screening Childhood Cancer Survivors https://www.skion.nl/workspace/uploads/vertaling-richtlijn-LATER-versie-final-okt-2014_2.pdf
Fellowship and Awards
2019 KIKA project: THYRO-Dynamics Study (Prospective study on thyroid function during treatment with chemotherapy in 600 children)
2019 Princess Maxima Grant; research grant for 4-year PhD student: “Building an organoid model for craniopharyngioma”
2009-2011 Fellowship kinderendocrinologie in het Emma Kinderziekenhuis AMC