dr. H.M. van Santen
- Endocrinology patient care
Research Programs
Biography
Biography
Dr. HM van Santen moved her career in 2013 to Utrecht to support the Máxima initiative and to coordinate the endocrine care for children with cancer in the Princess Máxima Center.
She has co-authored 59 publications on the endocrine effects of childhood cancer treatment, of which 32 as first or last author.
She is an associate professor and PI in the research program of Child Health, WKZ, UMCU and co-PI in the Máxima Center for Pediatric Oncology.
Her research program focuses on the endocrine and metabolic effects of children with craniopharyngioma, the acute and late effects of childhood cancer treatment on the endocrine system, and on pediatric thyroid cancer. The overall aim of her work is to preserve an intact endocrine system in children with neoplasms enabling normal growth and development into adulthood.
She is chair of the MC4 group Craniopharyngioma in the Máxima Center for Pediatric Oncology, chair of the Late Effects of Childhood Cancer International Guideline Harmonization Groups (IGHG) for thyroid and hypothalamic-pituitary disorders, and member of the IGHG working groups for male and female gonadal toxicity and preservation of fertility and metabolic syndrome. She is chair of the Dutch and the European Guideline for Thyroid cancer in children and the coordinator of the NFU/ ENDO-ERN expertise center Thyroid Tumors in Utrecht. She is member of the SIOP craniopharyngioma working group and the SIOP low grade glioma working group, the national consortium for Late effects of treatment for childhood thyroid carcinoma, the consortium of the Dexadagen-2 study, the Dutch Growth Hormone Advisory board and has a consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma.
Side Activities
2020 co-PI Prinses Maxima Center for Pediatric Oncology Utrecht
2019 BKO qualification UMCU
2019 Chair of the European Task Force for Recommendations of Treatment of Thyroid nodules and Carcinoma in Childhood
2016 – now Deputy educator ( plaatsvervangend opleider) of the clinical fellow pediatric endocrinology in the Wilhelmina Children’s Hospital, UMCU
2018 - now member of working group supportive care Princess Maxima Center
2017 - now member of fertility working group Princess Maxima Center
2016 - now Co-chair of the IGHG for surveillance of hypothalamic-pituitary disorders in Childhood Cancer Survivors
2016 - now Participant/ member of the working group of the IGHG working group for preservation of fertility in male childhood cancer survivors (in progress)
2016 – now Participant / working group lead of the IGHG working group for preservation of fertility in female childhood cancer survivors (in progress)
2016 - now Participant/ member of the working group of the IGHG recommendation for surveillance of the metabolic syndrome in childhood cancer survivors (in progress)
2016 - now Co-chair of the Dutch Guideline for Treatment of Thyroid nodules and cancer in children (in progress)
2016 - now Participant of the SIOP supportive care group
2016 - now Participant of the SIOP low grade glioma working group
2016 - now Participant of the national consortium for Late effects of treatment for childhood thyroid carcinoma ( PI T Links, UMCG)
2016 - now Participant of the consortium of the Dexadagen-2 study
2015 - now Participant of the Dutch Growth Hormone Advisory board (SEK)
2015 - now Consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma(www.cyberpoli.nl)
2015 – now Participant of the SKION LATER Recommendations for screening Childhood Cancer Survivors https://www.skion.nl/workspace/uploads/vertaling-richtlijn-LATER-versie-final-okt-2014_2.pdf
Fellowship and Awards
2019 KIKA project: THYRO-Dynamics Study (Prospective study on thyroid function during treatment with chemotherapy in 600 children)
2019 Princess Maxima Grant; research grant for 4-year PhD student: “Building an organoid model for craniopharyngioma”
2009-2011 Fellowship kinderendocrinologie in het Emma Kinderziekenhuis AMC
Research Output (90)
van Iersel Laura, van Santen Hanneke M, Potter Brian, Li Zhenghong, Conklin Heather M, Zhang Hui, Chemaitilly Wassim, Merchant Thomas E 1 dec 2020, In: Pediatric Blood & Cancer. 67 , p. e28723
van Santen Hanneke M, van de Wetering Marianne D, Bos Annelies M E, Vd Heuvel-Eibrink Marry M, van der Pal Helena J, Wallace William Hamish dec 2020, In: The pediatric clinics of North America. 67 , p. 1187-1202 16 p.
van Santen Hanneke M dec 2020, In: European Journal of Endocrinology. 183 , p. C15-C18
Nuijts Myrthe A, Veldhuis Nienke, Stegeman Inge, van Santen Hanneke M, Porro Giorgio L, Imhof Saskia M, Schouten-van Meeteren Antoinette Y N 1 okt 2020, In: PLoS ONE. 15 , p. e0240016
van Santen Hanneke M, Chemaitilly Wassim, Meacham Lillian R, Tonorezos Emily S, Mostoufi-Moab Sogol okt 2020, In: The pediatric clinics of North America. 67 , p. 1171-1186 16 p.
Lebbink C. A., Dekker B. L., Bocca G., Braat A. J.A.T., Derikx J. P.M., Dierselhuis M. P., de Keizer B., Kruijff S., Kwast A. B.G., van Nederveen F. H., Nieveen van Dijkum E. J.M., Nievelstein R. A.J., Peeters R. P., Terwisscha van Scheltinga C. E.J., Tissing W. J.E., van der Tuin K., Vriens M. R., Zsiros J., van Trotsenburg A. S.P., Links T. P., van Santen H. M. okt 2020, In: European Journal of Endocrinology. 183 , p. P11-P18
van Santen Hanneke M., Alexander Erik K., Rivkees Scott A., Frey Eva, Clement Sarah C., Dierselhuis Miranda P., Lebbink Chantal A., Links Thera P., Lorenz Kerstin, Peeters Robin P., Reiners Christoph, Vriens Menno R., Nathan Paul, Schneider Arthur B., Verburg Frederik 1 sep 2020, In: European Journal of Endocrinology. 183 , p. P1-P10
van Schaik Jiska, Begijn Dominique G A, van Iersel Laura, Vergeer Yvonne, Hoving Eelco W, Peeters Babette, van Santen Hanneke M 11 aug 2020, In: Obesity Facts. 13 , p. 361-370 10 p.
Clement Sarah C, Lebbink Chantal A, Klein Hesselink Mariëlle S, Teepen Jop C, Links Thera P, Ronckers Cecile M, van Santen Hanneke M aug 2020, In: European Journal of Endocrinology. 183 , p. 169-180 12 p.
van Schaïk Jiska, Van Roessel I. M.A.A., Schouten-van Meeteren Antoinette Y. N., van Iersel Laura, Clement S.C., Boot Annemieke M, Claahsen-van der Grinten Hedi L, Caron Huib N., Janssens G.O., van Vuurden Dannis G, Michiels Erna M., Granzen Bernd, Han KS, van Trotsenburg A. S. Paul, Vandertop W. Peter, Kremer Leontine C M, van Santen HM 24 feb 2020, 2 p.