dr. H.M. van Santen
dr. H.M. van Santen
- Endocrinology patient care
Research Programs
Biography
Biography
Dr. HM van Santen moved her career in 2013 to Utrecht to support the Máxima initiative and to coordinate the endocrine care for children with cancer in the Princess Máxima Center.
She has co-authored > 100 articles on the endocrine effects of childhood cancer treatment, craniopharyngioma and pediatric thyroid cancer.
She is an associate professor, PI and clinical scientist in the research program of Child Health, WKZ, UMCU and co-PI in the Máxima Center for Pediatric Oncology.
Her research program focuses on the endocrine and metabolic effects of children with severe disease such as childhood craniopharyngioma, the acute and late effects of childhood cancer treatment on the endocrine system, and on pediatric thyroid cancer. The overall aim of her work is to preserve an intact endocrine system in children with neoplasms enabling normal growth and development into adulthood.
She is chair of the SIOPe craniopharyngioma working group and of the MC4 group Craniopharyngioma in the Máxima Center for Pediatric Oncology. Also she chairs the Late Effects of Childhood Cancer International Guideline Harmonization Groups (IGHG) for thyroid and hypothalamic-pituitary disorders, and is member of the IGHG working groups for male and female gonadal toxicity and preservation of fertility and metabolic syndrome.
She is chair of the Dutch and the European Guideline for Thyroid cancer in children (ETA) and the coordinator of the NFU/ ENDO-ERN expertise center Thyroid Tumors in Utrecht.
Furthermore, Dr Hm van Santen is a member of the SIOP low grade glioma working group, the national consortium for Late effects of treatment for childhood thyroid carcinoma, the consortium of the Dexadagen-2 study, the Dutch Growth Hormone Advisory board and has a consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma.
Side Activities
2020 - now member of the WKZ Onderzoeksfonds Scientific Committee
2020 member of the Internal Grant committee Princess Maxima Center
2020 Chair SIOPe craniopharyngioma board
2020 Member of the Advisory board of the Academic Japanese Consortium for Juvenile Thyroid Cancer (JCJTC, president Dr Ohtsuru)
2020 co-PI Prinses Maxima Center for Pediatric Oncology Utrecht
2019 BKO qualification UMCU
2019 Chair of the European Task Force for Recommendations of Treatment of Thyroid nodules and Carcinoma in Childhood
2016 – now Deputy educator ( plaatsvervangend opleider) of the clinical fellow pediatric endocrinology in the Wilhelmina Children’s Hospital, UMCU
2018 - now member of working group supportive care Princess Maxima Center
2017 - now member of fertility working group Princess Maxima Center
2016 - now Co-chair of the IGHG for surveillance of hypothalamic-pituitary disorders in Childhood Cancer Survivors
2016 - now Participant/ member of the working group of the IGHG working group for preservation of fertility in male childhood cancer survivors (in progress)
2016 – now Participant / working group lead of the IGHG working group for preservation of fertility in female childhood cancer survivors (in progress)
2016 - now Participant/ member of the working group of the IGHG recommendation for surveillance of the metabolic syndrome in childhood cancer survivors (in progress)
2016 - now Co-chair of the Dutch Guideline for Treatment of Thyroid nodules and cancer in children (in progress)
2016 - now Participant of the SIOP supportive care group
2016 - now Participant of the SIOP low grade glioma working group
2016 - now Participant of the national consortium for Late effects of treatment for childhood thyroid carcinoma ( PI T Links, UMCG)
2016 - now Participant of the consortium of the Dexadagen-2 study
2015 - now Participant of the Dutch Growth Hormone Advisory board (SEK)
2015 - now Consultative function for the “Cyberpoli” for thyroid diseases and craniopharyngioma(www.cyberpoli.nl)
2015 – now Participant of the SKION LATER Recommendations for screening Childhood Cancer Survivors https://www.skion.nl/workspace/uploads/vertaling-richtlijn-LATER-versie-final-okt-2014_2.pdf
Fellowship and Awards
2020 ZonMW Stimuleringssubsidie "Implementatie van nieuw behandelalgoritme voor hypothalame obesitas bij kinderen met een supra-sellaire tumor"
2019 KIKA project: THYRO-Dynamics Study (Prospective study on thyroid function during treatment with chemotherapy in 600 children)
2019 Princess Maxima Grant; research grant for 4-year PhD student: “Building an organoid model for craniopharyngioma”
2009-2011 Fellowship kinderendocrinologie in het Emma Kinderziekenhuis AMC
Research Output (145)
Lebbink Chantal A, van den Bos Cor, Dierselhuis Miranda P, Fiocco Marta, Verrijn Stuart Annemarie A, Lentjes Eef G W M, Plasschaert Sabine L A, Tissing Wim J E, van Santen Hanneke M Mar 2023, In: Cancers. 15
van Santen Hanneke M., van Schaik Jiska, van Roessel Ichelle M.A.A., Beckhaus Julia, Boekhoff Svenja, Müller Hermann L. 14 Feb 2023, In: European Journal of Endocrinology. 188 , p. 1-12 12 p.
van Atteveld Jenneke E., de Winter Demi T.C., Pluimakers Vincent G., Fiocco Marta, Nievelstein Rutger A.J., Hobbelink Monique G.G., de Vries Andrica C.H., Loonen Jacqueline J., van Dulmen-den Broeder Eline, van der Pal Helena J., Pluijm Saskia M.F., Kremer Leontien C.M., Ronckers Cécile M., van der Heiden-van der Loo Margriet, Versluijs A. Birgitta, Louwerens Marloes, Bresters Dorine, van Santen Hanneke M., Olsson Daniel S., Hoefer Imo, van den Berg Sjoerd A.A., den Hartogh Jaap, Tissing Wim J.E., Neggers Sebastian J.C.M.M., van den Heuvel-Eibrink Marry M., Jan 2023, In: The Lancet Diabetes and Endocrinology. 11 , p. 21-32 12 p.
van Roessel Ichelle M A A, Bakker Boudewijn, van Santen Hanneke M, Chemaitilly Wassim 13 Dec 2022, In: Endocrine connections. 12
van Santen HM, Lebbink Chantal, Czarniecka Agnieszka, Dias Renuka P, Elisei Rossella, Izatt Louise, Krude Heiko, Links Thera P, Lorenz Kerstin, Luster Markus, Newbold Katherine, Piccardo Arnoldo, Sobrinho Simões Manuel, Takano Toru, van Trotsenburg A. S. Paul, Verburg Frederik A. 19 Nov 2022,
Van Atteveld Jenneke E., de Winter Demi T.C., Pluimakers Vincent, Fiocco M., Nievelstein Rutger Jan, Hobbelink MGG, Kremer Leontien, Ronckers Cécile, Grootenhuis Martha, Maurice-Stam Heleen, Tissing Wim, de Vries Andrica C, Loonen Jacqueline J, van Dulmen-den Broeder E., van der Pal Helena J H, Pluijm Saskia, Van Der Heiden-Van Der Loo M., Versluijs Birgitta, Louwerens Marloes, Bresters Dorine, van Santen HM, Höfer IE, Van Den Berg Sjoerd A., Hoeijmakers Jan H. J., Neggers Sebastian J C M M, van den Heuvel-Eibrink M.M. 15 Nov 2022, In: Blood. 140 , p. 6026–6027
de Winter Demi T.C., Van Atteveld Jenneke E., Pluimakers Vincent, Fiocco M., Nievelstein Rutger A. J., Hobbelink MGG, de Vries Andrica C, Loonen Jacqueline J, Van Dulmen-Den Broeder Eline, van der Pal Helena J H, Pluijm Saskia, Kremer Leontien, Ronckers Cécile, Van Der Heiden-Van Der Loo M., Olsson Daniel S., Höfer IE, Van Den Berg Sjoerd A., den Hartogh Jaap, Versluijs Birgitta, Tissing Wim, Neggers Sebastian J C M M, van den Heuvel-Eibrink M.M., van Santen HM, Louwerens Marloes, Bresters D. 15 Nov 2022, In: Blood. 140 , p. 922–923
van Hulst Annelienke M, van den Akker Erica L. T., Verwaaijen Emma, Fiocco M., Rensen Niki, van Litsenburg Raphaele R. L., Pluijm Saskia, Zwaan Michel, van Santen HM, Pieters Rob, Evers Andrea W M, Grootenhuis Martha, van den Heuvel-Eibrink M.M. 15 Nov 2022, In: Blood. 140 , p. 3162–3163
van Santen HM, Lebbink Chantal, Czarniecka Agnieszka, Dias Renuka P, Elisei Rossella, Izatt Louise, Krude Heiko, Links Thera P, Lorenz Kerstin, Luster Markus, Newbold Katherine, Piccardo Arnoldo, Sobrinho Simões Manuel, Takano Toru, van Trotsenburg A. S. Paul, Verburg Frederik A. 19 Oct 2022,
Kooijmans Esmee C.M., van der Pal Helena J.H., Pilon Maxime C.F., Pluijm Saskia M.F., van der Heiden-van der Loo Margriet, Kremer Leontien C.M., Bresters Dorine, van Dulmen-den Broeder Eline, van den Heuvel-Eibrink Marry M., Loonen Jacqueline J., Louwerens Marloes, Neggers Sebastian J.C., van Santen Hanneke M., Tissing Wim J.E., de Vries Andrica C.H., Kaspers Gertjan J.L., Veening Margreet A., Bökenkamp Arend, 6 Oct 2022, In: Scandinavian Journal of Clinical and Laboratory Investigation. 82 , p. 541-548 8 p.