prof. dr. W.W. (W.W.) van Solinge

Full Professor
prof. dr. W.W. (W.W.) van Solinge
  • Department of Clinical Chemistry and Haematology



Wouter van Solinge (1962) studied Pharmaceutical Sciences at Utrecht University. After finishing his studies in 1988, he moved to Copenhagen, Denmark for a period of four years to work at the University Hospital (Rigshospitalet). End of 1992, he started his residency at the Meander Medical Center in Amersfoort, to become a clinical chemist. He became a registered clinical chemist in February 1997 and accepted a job as clinical chemist and staff member both at the Meander Medical Center and at the University Medical Center St Radboud in Nijmegen. In September 1998, Van Solinge moved to the University Medical Center Utrecht, to work as clinical chemist and staff member at the Department of Clinical Chemistry and Haematology. In April 2000 he became Associate Head of Department and in April 2002, Head of Department. He became professor of Laboratory Medicine in December 2003. In 2004 he started the Utrecht Patient Oriented Database (UPOD), a translational database containing all data on patients treated at the UMC Utrecht, for research purposes.

In addition, among other, he was the Medical Director of the Division of Laboratories and Pharmacy from October 2007 and Chairman of the Division since June 2012 until September 2016.

Within the UMC Utrecht he is the Ambassador for eHealth & Big Data. In that capacity he is responsible for the corporate program Applied Data Analytics in Medicine (ADAM).


Research Output (244)

The interplay between drivers of erythropoiesis and iron homeostasis in rare hereditary anemias:Tipping the balance

Grootendorst Simon, de Wilde Jonathan, van Dooijeweert Birgit, van Vuren Annelies, van Solinge Wouter, Schutgens Roger, van Wijk Richard, Bartels Marije 2 feb 2021, In: International journal of molecular sciences. 22 17 p.

Neutrophil fluorescence in clozapine users is attributable to a 14kDa secretable protein

de With Sera A.J., Man Wai H., Maas Coen, Ten Berg Maarten, Cahn Wiepke, Koekman Arnold C., van Solinge Wouter W., Tak Tamar 1 okt 2020, In: Pharmacology research & perspectives. 8 , p. 1-8

Untargeted metabolic profiling in dried blood spots identifies disease fingerprint for pyruvate kinase deficiency

Van Dooijeweert Birgit, Broeks Melissa H, Verhoeven-Duif Nanda M, Van Beers Eduard J, Nieuwenhuis Edward E S, Van Solinge Wouter W, Bartels Marije, Jans Judith J, Van Wijk Richard 10 sep 2020, In: Haematologica. Online ahead of print , p. 1-20

Low-Density Lipoprotein Cholesterol Target Attainment in Patients With Established Cardiovascular Disease:Analysis of Routine Care Data

Groenhof T Katrien J, Kofink Daniel, Bots Michiel L, Nathoe Hendrik M, Hoefer Imo E, Van Solinge Wouter W, Lely A Titia, Asselbergs Folkert W, Haitjema Saskia 2 apr 2020, In: JMIR medical informatics. 8 , p. 1-12

Inappropriate laboratory testing in internal medicine inpatients:Prevalence, causes and interventions

Vrijsen B. E.L., Naaktgeboren C. A., Vos L. M., van Solinge W. W., Kaasjager H. A.H., ten Berg M. J. 1 mrt 2020, In: Annals of Medicine and Surgery. 51 , p. 48-53 6 p.

AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes

Rab Minke A E, van Oirschot Brigitte A, Kosinski Penelope A, Hixon Jeffrey, Johnson Kendall, Chubukov Victor, Dang Lenny, Pasterkamp Gerard, van Straaten Stephanie, van Solinge Wouter W, van Beers Eduard J, Kung Charles, van Wijk Richard 23 jan 2020, In: Haematologica. 106 , p. 238-249 12 p.

Fragile neutrophils in surgical patients:A phenomenon associated with critical illness

Hesselink Lillian, Spijkerman Roy, Hellebrekers Pien, van Bourgondiën Robert J, Blasse Enja, Haitjema Saskia, Huisman Albert, van Solinge Wouter W, Van Wessem Karlijn J P, Koenderman Leo, Leenen Luke P H, Hietbrink Falco 2020, In: PLoS ONE. 15 19 p.

Reticulated Platelets as Predictor of Myocardial Injury and 30 Day Mortality After Non-cardiac Surgery

Meershoek Armelle J A, Leunissen Tesse C, van Waes Judith A R, Klei Wilton A, Huisman Albert, de Groot Mark C H, Hoefer Imo E, van Solinge Wouter W, Moll Frans L, de Borst Gert J 4 dec 2019, In: European Journal of Vascular and Endovascular Surgery. 59 , p. 309-318 10 p.

A computerised decision support system for cardiovascular risk management 'live' in the electronic health record environment:development, validation and implementation-the Utrecht Cardiovascular Cohort Initiative

Groenhof T K J, Rittersma Z H, Bots M L, Brandjes M, Jacobs J J L, Grobbee D E, van Solinge W W, Visseren F L J, Haitjema S, Asselbergs F W, 1 aug 2019, In: Netherlands Heart Journal. 27 , p. 435-442 8 p.

Unbound Fraction of Clozapine Significantly Decreases with Elevated Plasma Concentrations of the Inflammatory Acute-Phase Protein Alpha-1-Acid Glycoprotein

Man Wai Hong, Wilting Ingeborg, Heerdink Eibert R., Hugenholtz Gerard W.K., Bognár Tim, ten Berg Maarten J., van Solinge Wouter W., Egberts Toine A.C.G., van Maarseveen Erik M. 1 aug 2019, In: Clinical Pharmacokinetics. 58 , p. 1069-1075 7 p.

All research output

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