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prof. dr. F. (Femke) van Wijk

Full Professor
  1. Contact
  2. Research Programs
  3. Biography
  4. Side Activities
  5. Fellowship and Awards
  6. Research Output
prof. dr. F. (Femke) van Wijk
E. fwijk@umcutrecht.nl
  • Laboratory for Translational Immunology (LTI)

Research Programs

Biography

Biography

Femke van Wijk obtained her PhD on mechanisms of oral tolerance and allergic sensitization to peanut at the Utrecht University in 2006. After her first postdoctoral training in human immunology in the lab of Prof Prakken she obtained a KNAW fellowship for a 2-year postdoc in the lab of Dr. Cheroutre in the La Jolla Institute for Allergy and Immunology in San Diego. In this basic immunology institute she worked on T cell plasticity and tissue-controlled T cell differentiation. After being awarded a VENI fellowship in 2010, she moved to the UMC Utrecht to further develop her research program in translational immunology. For her research on how antigen presenting cells sabotage T cell regulation in inflammation van Wijk was awarded a VIDI grant (2014) and starting 2015 she has been appointed Associate Professor. Her research is embedded in the Laboratory of Translational Immunology and Pediatric Immunology group and addresses conceptual and mechanistic immunological questions with a strong link to the clinic. She is participating in several worldwide networks including Eureka Institute for Translational Medicine (www.eurekainstitute.org) and Understanding Childhood Arthritis Worldwide Network (www.ucan-u.org) that are aimed at (international) exchanges and training of people, knowledge sharing, and enhancing reproducibility of human data.

 

Side Activities

  • Member scientific committee ZonMW Off-road program

Fellowship and Awards

  • PhD Supervisor (co-promotor) of the year 2017, Graduate School of Life Sciences

    Stimulerings Associate Professorship UMCU (2015)

    KNAW fellowship Ter Meulen Fund

    NWO VIDI (2014)

    NWO Veni (2010)

     

Research Output (82)

Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor Tregs

Wienke Judith, Brouwers Laura, van der Burg Leone M, Mokry Michal, Scholman Rianne C, Nikkels Peter G J, van Rijn Bas B, van Wijk Femke 18 aug 2020, In: JCI Insight. 5 , p. 1-21

Endothelial and Inflammation Biomarker Profiles at Diagnosis Reflecting Clinical Heterogeneity and Serving as a Prognostic Tool for Treatment Response in Two Independent Cohorts of Patients With Juvenile Dermatomyositis

Wienke Judith, Pachman Lauren M, Morgan Gabrielle A, Yeo Joo Guan, Amoruso Maria C, Hans Victoria, Kamphuis Sylvia S M, Hoppenreijs Esther P A H, Armbrust Wineke, van den Berg J Merlijn, Hissink Muller Petra C E, Gelderman Kyra A, Arkachaisri Thaschawee, van Wijk Femke, van Royen-Kerkhof Annet 26 feb 2020, In: Arthritis & Rheumatology. 72 , p. 1214-1226 13 p.

Dupilumab is very effective in a large cohort of difficult-to-treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry

Ariens Lieneke F. M., van der Schaft Jorien, Bakker Daphne S., Balak Deepak, Romeijn Margreet L. E., Kouwenhoven Tessa, Kamsteeg Marijke, Giovannone Barbara, Drylewicz Julia, van Amerongen Cynthia Catalina Aurora, Delemarre Evelien M., Knol Edward F., van Wijk Femke, Nierkens Stefan, Thijs Judith L., Schuttelaar Marie L. A., de Bruin-Weller Marjolein S. 1 jan 2020, In: Allergy. 75 , p. 116-126 11 p.

Colonic mucosal kinase activity, cytokine and chemokine profiles in inflammatory bowel disease

Brand E., Roosenboom B., Fernandez B. Malvar, Lutter L., van Koolwijk E., van Lochem E. G., Horje C. S. Horjus Talabur, Reedquist K. A., van Wijk F., Oldenburg B. jan 2020, In: Journal of Crohn's & Colitis. 14 , p. S139-S140

IgA coating of intestinal microbiota is associated with inflammatory bowel disease in twin pairs discordant for inflammatory bowel disease

Brand E., Laenen Y., van Wijk F., de Zoete M., Oldenburg B. jan 2020, In: Journal of Crohn's & Colitis. 14 , p. S010-S011

Confirmation of multiple endotypes in atopic dermatitis based on serum biomarkers

Bakker Daphne S, Nierkens Stefan, Knol Edward F, Giovannone Barbara, Delemarre Eveline M, van der Schaft Jorien, van Wijk Femke, de Bruin-Weller Marjolein S, Drylewicz Julia, Thijs Judith L 2020, In: The Journal of Allergy and Clinical Immunology. 147 , p. 189-198 10 p.

Endotyping of adult and paediatric atopic dermatitis; is it one disease?

Thijs J., Bakker D., Delemarre E., de Graaf M., Knol E., Drylewicz J., van Wijk F., Nierkens S., de Bruin-Weller M. sep 2019, In: Journal of Investigative Dermatology. 139 , p. S285-S285

The identification of CCL18 as biomarker of disease activity in localized scleroderma

Mertens J. S., de Jong E. M.G.J., van den Hoogen L. L., Wienke J., Thurlings R. M., Seyger M. M.B., Hoppenreijs E. P.A.H., Wijngaarde C. A., van Vlijmen-Willems I. M.J.J., van den Bogaard E., Giovannone B., van Wijk F., van Royen-Kerkhof A., Marut W., Radstake T. R.D. 1 jul 2019, In: Journal of Autoimmunity. 101 , p. 86-93 8 p.

T-Cell Compartmentalization and Functional Adaptation in Autoimmune Inflammation: Lessons From Pediatric Rheumatic Diseases.

Mijnheer Gerdien, van Wijk Femke mei 2019, In: Frontiers in Immunology [E]. 10

Dupilumab:Eerste resultaten vanuit het BioDay-register

Ariëns Lieneke F.M., van der Schaft J., Bakker D. S., Balak D. M.W., Giovannone B., Romeijn M., Kouwenhoven T., Kamsteeg M., Drylewicz J., van Wijk F., Nierkens Stefan, Thijs J. L., Schuttelaar M. L., de Bruin-Weller M. S. 1 apr 2019, In: Nederlands Tijdschrift voor Dermatologie en Venereologie. 29 , p. 29-34 6 p.

All research output