dr. J.J.C. (Joost) Verhoeff
dr. J.J.C. (Joost) Verhoeff
- Department of Radiotherapy
Research Programs
Biography
Biography
View my YouTube research presentation (in Dutch):
MRI-geleide radiotherapie in Utrecht: Harder, Better, Faster, Stronger https://youtu.be/aJerM2wQoKI?t=152
Performing research is expensive. If you want to support us to speed things up, please contact me.
T. 088 - 75 588 00 E. j.j.c.verhoeff-10@umcutrecht.nl
My lab's mission is to redefine Standard Radiotherapy
As radiation oncologists, we want to treat cancer patients with high precision radiotherapy. The UMC Utrecht has the right team and right machinery for this (3x MRI-linac, 10x CT-linac). My lab's goal is to design the best cancer treatment for each patient. Some patients want to live as long as possible regardless of treatment side effects, others want quality of life. To find balance is key.
The UMC Utrecht department of Radiation Oncology is a terrific place to do clinical research, as it is even the birthplace of the MRI-linac. Next, the Radiation Oncology department harbours 2 1.5T MRI systems, a 3.0T MRI, a 7.0T MRI and a MRI/PET scanner.
Joost Verhoeff subspecialized in treatment of brain tumors, lung cancer and cardiac SBRT. About half of his time he spends on research as associate professor.
Brain tumors:
- Increasing quality of life by compact but extremely precise focused radiation treatment
- Increasing overall survival by combining better treatment modalities
- Principal Investigator of ZonMW funded GOLD trial (dutch info), 30x2Gy+TMZ versus 6x6Gy+TMZ for primary GBM (responsible researcher drs. Arthur van der Boog)
- Principal Investigator of KWF funded RISinG trial (dutch info), 10x3.5Gy versus 4x7.5Gy for recurrent GBM (responsible researcher drs. Arthur van der Boog)
Brain metastases:
- Finding best treatments for each specific patient: personalized medicine.
- Increasing quality of life by incorporating MR-guided treatment post operative (MRI-linac)
- Coimbra brain metastasis prospective cohort (website, clinicaltrials.gov) (responsible researcher drs. Fia Cialdella)
Lung cancer:
- Better predicting patient survival and toxicity by smart analyses
- Increasing quality of life by incorporating MR-guided treatment (MR-Linac)
- U-color prospective cohort, for all lung cancer patients that receive radiotherapy
Cardiac Ablative SBRT:
- In the lead of a consortium of 30 European hospitals we develop strategies to treat Ventricular Tachycardia in the STOPSTORM.eu framework (Principal Investigator, EU H2020 grant).
Postdocs:
- Szabolcs David PhD (brain tumors, imaging)
- Jacqueline Pomp MD PhD, radiation oncologist, (lung cancer and deep learning)
- Peter van Rossum MD PhD MSc, resident radiation oncologist (MRI-linac, epidemiology, lung cancer)
PhD students:
- Eva van Grinsven MSc (neuro-psychology, brain tumors)
- Arthur van der Boog BS (brain tumors, clinical trials)
- Belle van Duin MD (melanoma, imaging, pathology)
- Fia Cialdella MD (brain metastases, neuro-oncology)
Residents radiation oncology performing research:
- Joyce Lodeweges MD (lung cancer)
- Max Peters MD PhD MSc (epidemiology, lung cancer)
- Pim Damen MD (immunotherapies)
- Emma Wolters MD PhD (neuro oncology)
- Rosa Sleddering MD (neuro oncology)
Students (medical, biomedical, informatics):
- Michelle Sierts (MR-Linac for brain tumors)
- Karlijn Smitt (brain tumors)
- Lucie Egberink (lung cancer)
- Myra van Laar (lung cancer)
Former group members (medical, biomedical, informatics):
- Steven Nagtegaal MD PhD (brain tumors, cognitive changes)
- Wouter van Amsterdam MD PhD (deep learning, lung cancer)
- Selena Huisman (brain tumor imaging)
- Victor Wasser (brain tumor imaging)
- Salah Gasle (brain tumor imaging)
- Mathijs Tomassen (lung cancer)
- Sjors Witteveen (lung cancer)
- Hajo Boersma (psychiatric disorders and radiotherapy)
- Hugo van Joolingen (lung cancer)
- Anne van der Tuin (MR-Linac for lung cancer)
- Eva Swinkels (lung cancer)
- Marnix Rading MD (lung cancer)
- Laura Merckel MD PhD (MRI-linac lung cancer)
- Bas Arends (deep learning for spine tumor treatment)
- Jasper Hennecken (spinal imaging)
- Céline Bogers (lung cancer)
- Eliza van Wulfften Palthe (brain metastases)
- Anouk Steennis (brain tumors)
- Ali Ghannam (brain metastases cohort)
- Emma Nessen (brain metastases)
- Marc Pijper (lung cancer)
- Cathalijne Post (brain tumors)
- Robin Schuijlenburg (brain tumors)
- Merel Kraak (lung cancer)
- Suzanne Vellinga (lung cancer)
- Netanja Harlianto (lung cancer)
- Yannic Hanekamp (Covid treatment)
- Sjors Wagemakers (pain meassurement)
- Max van Essen (brain tumors)
- Chris Hammerstein (survival analyses)
Full list of publications on PubMed: click here (automatic list is incomplete)
Research Output (152)
van Grinsven Eva E, de Leeuw Jordi, for Neuroimaging, Amsterdam, Netherlands Spinoza, Verhoeff Joost J C, van Zandvoort Martine J E, Cho Junghun, Philippens Marielle E P, Bhogal Alex A 28 Aug 2023, In: Cancers. 15 26 p.
Stevens Raoul R F, Hazelaar Colien, Fast Martin F, Mandija Stefano, Grehn Melanie, Cvek Jakub, Knybel Lukas, Dvorak Pavel, Pruvot Etienne, Verhoeff Joost, Blanck Oliver, van Elmpt Wouter 4 Aug 2023, In: Radiotherapy & Oncology. 188 , p. 109844
van Opijnen Mark P, de Vos Filip Y F, Nabuurs Rob J A, Snijders Tom J, Nandoe Tewarie Rishi D S, Taal Walter, Verhoeff Joost J C, van der Hoeven Jacobus J M, Broekman Marike L D 1 Aug 2023, In: Neuro-Oncology Practice. 10 , p. 360-369 10 p.
Nijskens Lotte, van den Berg Cornelis A T, Verhoeff Joost J C, Maspero Matteo 18 Jul 2023, In: Physica Medica. 112
Huttinga Niek Ricardo Ferdinand, Akdag Osman, Fast Martin F, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Van den Berg Cornelis A T, Sbrizzi Alessandro, Mandija Stefano 20 Jun 2023, In: Physics in medicine and biology. 68 14 p.
Peters Max, Boersma Hajo W., van Rossum Peter S.N., van Oort Jasper, Cahn Wiepke, Verhoeff Joost J.C. May 2023, In: Clinical and translational radiation oncology. 40 7 p.
Damen Pim J J, Verhoeff Joost J C 31 Mar 2023, In: Translational Cancer Research. 12 , p. 688-691 4 p.
Tomassen Mathijs L, Damen Pim J J, Verkooijen Helena M, Peters Max, van der Stap Janneke, van Lindert Anne S R, Verhoeff Joost J C, van Rossum Peter S N 16 Mar 2023, In: Acta Oncologica. 62 , p. 237-244 8 p.
Grehn Melanie, Mandija Stefano, Miszczyk Marcin, Krug David, Tomasik Bartłomiej, Stickney Kristine E, Alcantara Pino, Alongi Filippo, Anselmino Matteo, Aranda Ricardo Salgado, Balgobind Brian V, Boda-Heggemann Judit, Boldt Leif-Hendrik, Bottoni Nicola, Cvek Jakub, Elicin Olgun, De Ferrari Gaetano Maria, Hassink Rutger J, Hazelaar Colien, Hindricks Gerhard, Hurkmans Coen, Iotti Cinzia, Jadczyk Tomasz, Jiravsky Otakar, Jumeau Raphaël, Buus Kristiansen Steen, Levis Mario, López Manuel Algara, Martí-Almor Julio, Mehrhof Felix, Møller Ditte Sloth, Molon Giulio, Ouss Alexandre, Peichl Petr, Plasek Jiri, Postema Pieter G, Quesada Aurelio, Reichlin Tobias, Rordorf Roberto, Rudic Boris, Saguner Ardan M, Ter Bekke Rachel M A, Torrecilla José López, Troost Esther G C, Vitolo Viviana, Andratschke Nicolaus, Zeppenfeld Katja, Blamek Slawomir, Fast Martin, de Panfilis Ludovica, Blanck Oliver, Pruvot Etienne, Verhoeff Joost J C 6 Mar 2023, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 25 , p. 1284-1295 12 p.
Ter Maat Laurens S, van Duin Isabella A J, Elias Sjoerd G, Leiner Tim, Verhoeff Joost J C, Arntz Eran R A N, Troenokarso Max F, Blokx Willeke A M, Isgum Ivana, de Wit Geraldine A, van den Berkmortel Franchette W P J, Boers-Sonderen Marye J, Boomsma Martijn F, van den Eertwegh Fons J M, de Groot Jan Willem B, Piersma Djura, Vreugdenhil Art, Westgeest Hans M, Kapiteijn Ellen, van Diest Paul J, Pluim Josien P W, de Jong Pim A, Suijkerbuijk Karijn P M, Veta Mitko 24 Feb 2023, In: European Journal of Cancer. 185 , p. 167-177 11 p.