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dr. J.J.C. (Joost) Verhoeff Associate Professor - medical

  • Radiotherapy (research)
  • Department of Radiotherapy

J.J.C. Verhoeff


Research Programs


My mission is to redefine Standard Radiotherapy

As a radiation oncologist, I treat cancer patients with high precision radiotherapy. The UMC Utrecht has the right machinery for this (2x MRI-linac, 10x CT-linac). My goal is providing the best cancer treatment. Some patients want to live as long as possible regardless of treatment side effects, others want quality of life. To find balance is key.

The UMC Utrecht department of radiation oncology is a terrific place to spend my days, as it is even the birthplace of the MRI-linac.

I subspecialized in treatment of brain tumors and lung cancer. About half of my time I spend on research as associate professor.


Brain tumors:

  • Increasing quality of life by shorter but better focused radiation treatment
  • Increasing overall survival by combining better treatment modalities

Brain metastases:

  • Finding best treatments for each specific patient: personalized medicine.
  • Increasing quality of life by incorporating MR-guided treatment post operative (MRI-linac)

Lung cancer:

  • Better predicting patient survival by deep learning
  • Increasing quality of life by incorporating MR-guided treatment (MR-Linac)

Cardiac Ablative SBRT:

  • In collaboration with 17 other European hospitals we develop strategies to treat Ventricular Tachycardia in the STOPSTORM framework.



  • Szabolcs David (brain tumors)

PhD students:

  • Steven Nagtegaal MD (brain tumors)
  • Wouter van Amsterdam MD (deep learning, lung cancer)
  • Eva van Grinsven MSc (brain tumors)
  • Arthur van der Boog BS (brain tumors)

Residents radiation oncology performing research:

  • Marnix Rasing MD (lung cancer)
  • Laura Merckel MD PhD (MRI-linac lung cancer)
  • Joyce Lodeweges MD (lung cancer)
  • Max Peters MD PhD (epidemiology, lung cancer)
  • Peter van Rossum MD PhD (MRI-linac, epidemiology, lung cancer)
  • Pim Damen MD (immunotherapies)
  • Christa Gadella MD (brain tumors)


  • Alexander van Hulsbergen BS (brain tumors)
  • Daniel Versnel (brain tumors)
  • Myra van Laar (lung cancer)


Full list of publications on PubMed: click here (automatic list is incomplete)

Research Output (51)

Impact of body fat distribution and sarcopenia on the overall survival in patients with spinal metastases receiving radiotherapy treatment:a prospective cohort study

Pielkenrood B J, van Urk P R, van der Velden J M, Kasperts N, Verhoeff J J C, Bol G H, Verkooijen H M, Verlaan J J mrt 2020, In: Acta Oncologica. 59 , p. 291-297 7 p.

Eliminating biasing signals in lung cancer images for prognosis predictions with deep learning

van Amsterdam W. A. C., Verhoeff J. J. C., de Jong P. A., Leiner T., Eijkemans M. J. C. 10 dec 2019, In: NPJ DIGITAL MEDICINE. 2 , p. 122

Preoperative Prediction of Incomplete Resection in Non-Small Cell Lung Cancer: An Externally Validated Clinical Nomogram

Rasing M., Peters M., Moreno A., Hofman E., Herder J., Welvaart P., Schramel Franz M N H, Lodeweges J., Lin Steven H, Verhoeff J., Van Rossum P. okt 2019, In: Journal of Thoracic Oncology. 14 , p. S623-S623

Significance of Programmed Death Receptor Ligand One Expression in Brain Metastases of Non-Small Cell Lung Carcinoma

Hulsbergen A., Mammi M., Nagtegaal S., Verhoeff J., Smith T., Phillips J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E78-E78

A Multi-Institutional Estimation of Interobserver Variability in Glioblastoma Delineation in the EORTC-1709-BTG /CCTG CE.8 Trial

Kaidar-Person O., Saez J., Andratschke N., de Abrunhosa Branquinho A. N., Clementel E., Corning C., Hurkmans C., Monti A. F., Roth P., Verhoeff J., Dhermain F. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E617-E618

Comparing survival predicted by the diagnosis-specific Graded Prognostic Assessment (DS-GPA) to actual survival in patients with 1-10 brain metastases treated with stereotactic radiosurgery

Nagtegaal Steven, Claes An, Suijkerbuijk Karijn, Schramel Franz, Snijders Tom, Verhoeff Joost 1 sep 2019, In: Radiotherapy & Oncology. 138 , p. 173-179 7 p.

Occurrence of an Abscopal Radiation Recall Phenomenon in a Glioblastoma Patient Treated with Nivolumab and Re-Irradiation

Van Seggelen Wouter O., De Vos Filip Y., Röckmann Heike, Van Dijk Marijke R., Verhoeff Joost J.C. 1 sep 2019, In: Case Reports in Oncology. 12 , p. 896-900 5 p.

Any Radiation Dose to the Hippocampus Leads to Local Volume Loss in a Dose-Time-Dependent Way

Nagtegaal S., David S., Philippens M., Leemans A., Verhoeff J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E104-E105

A Multi-Institutional Estimation of Interobserver Variability in Glioblastoma Treatment Planning in the EORTC-1709-BTG / CCTG CE.8 trial

Monti A. F., de Abrunhosa Branquinho A. N., Andratschke N., Clementel E., Corning C., Dhermain F., Hurkmans C., Kaidar-Person O., Roth P., Saez J., Verhoeff J. 1 sep 2019, In: International Journal of Radiation Oncology Biology Physics. 105 , p. E619-E619

Brain and Head-and-Neck MRI in Immobilization Mask:A Practical Solution for MR-Only Radiotherapy

Mandija Stefano, D'Agata Federico, Navest Robin J M, Sbrizzi Alessandro, Tijssen Rob H N, Philippens Marielle E P, Raaijmakers Cornelis P J, Seravalli Enrica, Verhoeff Joost J C, Lagendijk Jan J W, van den Berg Cornelis A T 17 jul 2019, In: Frontiers in oncology. 9

All Research Output (51)
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