dr. A. (Aryan) Vink

dr. A. (Aryan) Vink

Assistant Professor - medical
dr. A. (Aryan) Vink
  • Department of Pathology

Research Programs

Circulatory Health



After his medical training at the Free University in Amsterdam, Aryan Vink studied inflammation in atherosclerosis at the Laboratory for Experimental Cardiology of the UMC Utrecht which led to a thesis. Fascinated by the pathophysiology and microscopic world behind diseases he decided to become a pathologist and finished his residency in 2007. Currently he is a staff pathologist with special interest in Cardiovascular, Pulmonary and Autopsy pathology.

At the Pathology Department of UMC Utrecht we have one of the largest and best documented cardiac tissue biobanks of the world. Based on this cardiac tissue biobank the research of Aryan Vink focuses on the phenotype – genotype correlation in cardiomyopathies. In addition he works in close collaboration with researchers from the Hubrecht Laboratory to validate findings of basic myocardial research in human tissue from the biobank. Finally he is the consulting pathologist for the Athero-Express biobank.

On the topic of his other specialization, Pulmonary Pathology, he is involved in the continuous process of implementation of new diagnostic tests in lung cancer pathology to come to optimal personalized state-of-the-art treatment of lung cancer patients in the UMC Utrecht.


Research Output (191)

Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model

Gaar-Humphreys Karen R, Spanjersberg Talitha C F, Santarelli Giorgia, Grinwis Guy C M, Szatmári Viktor, Roelen Bernard A J, Vink Aryan, van Tintelen J Peter, Asselbergs Folkert W, Fieten Hille, Harakalova Magdalena, van Steenbeek Frank G 1 Jul 2022, In: Animals : an open access journal from MDPI. 12 , p. 1-18

Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

Wehrens Martijn, de Leeuw Anne E., Wright-Clark Maya, Eding Joep E.C., Boogerd Cornelis J., Molenaar Bas, van der Kraak Petra H., Kuster Diederik W.D., van der Velden Jolanda, Michels Michelle, Vink Aryan, van Rooij Eva 10 May 2022, In: Cell Reports. 39 , p. 1-22

Radiography and Computed Tomography Detection of Intimal and Medial Calcifications in Leg Arteries in Comparison to Histology

Vos Annelotte, Vink Aryan, Kockelkoren Remko, Takx Richard A P, Celeng Csilla, Mali Willem P T M, Isgum Ivana, Bleys Ronald L A W, de Jong Pim A May 2022, In: Journal of Personalized Medicine. 12 , p. 1-7

Characteristics and time course of acute and chronic myocardial lesion formation after electroporation ablation in the porcine model

Neven Kars, van Driel Vincent J.H.M., Vink Aryan, du Pré Bastiaan C., van Wessel Harry, Füting Anna, Doevendans Pieter A., Wittkampf Fred H.M., van Es René Mar 2022, In: Journal of Cardiovascular Electrophysiology. 33 , p. 360-367 8 p.

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

Pei J, Schuldt M, Nagyova E, Gu Z, El Bouhaddani S, Yiangou L, Jansen M, Calis J J A, Dorsch L M, Blok C Snijders, van den Dungen N A M, Lansu N, Boukens B J, Efimov I R, Michels M, Verhaar M C, de Weger R, Vink A, van Steenbeek F G, Baas A F, Davis R P, Uh H W, Kuster D W D, Cheng C, Mokry M, van der Velden J, Asselbergs F W, Harakalova M Dec 2021, In: Clinical Epigenetics. 13 , p. 1-20

Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in Mice

Kessler Elise L., Wang Jiong Wei, Kok Bart, Brans Maike A., Nederlof Angelique, van Stuijvenberg Leonie, Huang Chenyuan, Vink Aryan, Arslan Fatih, Efimov Igor R., Lam Carolyn S.P., Vos Marc A., de Kleijn Dominique P.V., Fontes Magda S.C., van Veen Toon A.B. 1 Nov 2021, In: International journal of molecular sciences. 22 , p. 1-13

Can automatic image analysis replace the pathologist in cardiac allograft rejection diagnosis?

Veta Mitko, van Diest Paul J, Vink Aryan 21 Jun 2021, In: European heart journal. 42 , p. 2370-2372 3 p.

False-negative programmed death-ligand 1 immunostaining in ethanol-fixed endobronchial ultrasound-guided transbronchial needle aspiration specimens of non-small-cell lung cancer patients

Koomen Bregje M, Vreuls Willem, de Boer Mirthe, de Ruiter Emma J, Hoelters Juergen, Vink Aryan, Willems Stefan M 8 Jun 2021, In: Histopathology. 79 , p. 480-490 11 p.

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

Cuello Friederike, Knaust Anika E, Saleem Umber, Loos Malte, Raabe Janice, Mosqueira Diogo, Laufer Sandra, Schweizer Michaela, van der Kraak Petra, Flenner Frederik, Ulmer Bärbel M, Braren Ingke, Yin Xiaoke, Theofilatos Konstantinos, Ruiz-Orera Jorge, Patone Giannino, Klampe Birgit, Schulze Thomas, Piasecki Angelika, Pinto Yigal, Vink Aryan, Hübner Norbert, Harding Sian, Mayr Manuel, Denning Chris, Eschenhagen Thomas, Hansen Arne 7 Jun 2021, In: Embo Molecular Medicine. 13 , p. 1-19

Donor-Derived Testicular Germ Cell Cancer in a Heart Transplant Recipient

Oerlemans Marish I.F.J., Groenewegen Gerard, Vink Aryan, van Laake Linda W., van der Kaaij Niels P., de Jonge Nicolaas Jun 2021, In: JACC: CardioOncology. 3 , p. 322-325 4 p.

All research output

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