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dr. A. (Aryan) Vink

Assistant Professor - medical

  • Department of Pathology

dr. A. (Aryan) Vink

Research Programs

Biography

After his medical training at the Free University in Amsterdam, Aryan Vink studied inflammation in atherosclerosis at the Laboratory for Experimental Cardiology of the UMC Utrecht which led to a thesis. Fascinated by the pathophysiology and microscopic world behind diseases he decided to become a pathologist and finished his residency in 2007. Currently he is a staff pathologist with special interest in Cardiovascular, Pulmonary and Autopsy pathology.

At the Pathology Department of UMC Utrecht we have one of the largest and best documented cardiac tissue biobanks of the world. Based on this cardiac tissue biobank the research of Aryan Vink focuses on the phenotype – genotype correlation in cardiomyopathies. In addition he works in close collaboration with researchers from the Hubrecht Laboratory to validate findings of basic myocardial research in human tissue from the biobank. Finally he is the consulting pathologist for the Athero-Express biobank.

On the topic of his other specialization, Pulmonary Pathology, he is involved in the continuous process of implementation of new diagnostic tests in lung cancer pathology to come to optimal personalized state-of-the-art treatment of lung cancer patients in the UMC Utrecht.

 

Research Output (165)

Plasma Immunoglobulin Levels Prior to Cardiac Transplantation are Associated with Post-Transplantation Survival

van den Hoogen P., Huibers M. M., van den Dolder F. W., de Weger R. A., Siera E., de Jonge N., Doevendans P. A., Sluijter J. P., de Jager S. C., Vink A. apr 2020, In: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 39 , p. S500-S501

The Netherlands Arrhythmogenic Cardiomyopathy Registry:design and status update

Bosman L. P., Verstraelen T. E., van Lint F. H.M., Cox M. G.P.J., Groeneweg J. A., Mast T. P., van der Zwaag P. A., Volders P. G.A., Evertz R., Wong L., de Groot N. M.S., Zeppenfeld K., van der Heijden J. F., van den Berg M. P., Wilde A. A.M., Asselbergs F. W., Hauer R. N.W., te Riele A. S.J.M., van Tintelen J. P., Baas A. F., Barge-Schaapveld D. Q.C.M., Boekholdt S. M., Cramer M. J.M., Dooijes D., Jongbloed J. D.H., Loh P., Planken R. N., Prakken N. H.J., van der Smagt J. J., van der Wal A. C., Teske A. J., van Veen T. A.B., Velthuis B. K., Vink A., Yap S. C., 1 okt 2019, In: Netherlands Heart Journal. 27 , p. 480-486 7 p.

Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure

van den Hoogen Patricia, de Jager Saskia C.A., Huibers Manon M.H., Schoneveld Arjan H., Puspitasari Yustina M., Valstar Gideon B., Oerlemans Marish I.F.J., de Weger Roel A., Doevendans Pieter A., den Ruijter Hester M., Laman Jon D., Vink Aryan, Sluijter Joost P.G. 26 sep 2019, In: Journal of Cellular and Molecular Medicine. 23 , p. 7505-7516 12 p.

Diagnosis of myocardial infarction at autopsy:AECVP reappraisal in the light of the current clinical classification

Michaud Katarzyna, Basso Cristina, d'Amati Giulia, Giordano Carla, Kholová Ivana, Preston Stephen D, Rizzo Stefania, Sabatasso Sara, Sheppard Mary N, Vink Aryan, van der Wal Allard C, 14 sep 2019, In: Virchows Archives. 476 , p. 179-194 16 p.

Conserved NPPB plus Border Zone Switches From MEF2-to AP-1-Driven Gene Program

van Duijvenboden Karel, de Bakker Dennis E M, Man Joyce C K, Janssen Rob, Günthel Marie, Hill Matthew C, Hooijkaas Ingeborg B, van der Made Ingeborg, van der Kraak Petra H, Vink Aryan, Creemers Esther E, Martin James F, Barnett Phil, Bakkers Jeroen, Christoffels Vincent M 9 sep 2019, In: Circulation. 140 , p. 864-879 16 p.

UNRAVEL:big data analytics research data platform to improve care of patients with cardiomyopathies using routine electronic health records and standardised biobanking

Sammani A., Jansen M., Linschoten M., Bagheri A., de Jonge N., Kirkels H., van Laake L. W., Vink A., van Tintelen J. P., Dooijes D., te Riele A. S.J.M., Harakalova M., Baas A. F., Asselbergs F. W. 1 sep 2019, In: Netherlands Heart Journal. 27 , p. 426-434 9 p.

Integrated analysis of transcriptional regulation in PLN R14del cardiomyopathy

Pei J., Harakalova M., Nagyova E., Gho J. M. I. H., Sepehrkhouy S., van Dinter J., van Mil A., Buijsrogge M. P., de Jonge N., Huibers M. M., Nieuwenhuis E. E. S., den Ruijter H. M., Pasterkamp G., Doevendans P. A., Hajjar R., Mercola M., Sluijter J. P. G., de Weger R. A., Cheng C., Vink A., Mokry M., Asselbergs F. W. jul 2019, In: European Journal of Human Genetics. 27 , p. 790-791

The Translational Landscape of the Human Heart

van Heesch Sebastiaan, Witte Franziska, Schneider-Lunitz Valentin, Schulz Jana F, Adami Eleonora, Faber Allison B, Kirchner Marieluise, Maatz Henrike, Blachut Susanne, Sandmann Clara-Louisa, Kanda Masatoshi, Worth Catherine L, Schafer Sebastian, Calviello Lorenzo, Merriott Rhys, Patone Giannino, Hummel Oliver, Wyler Emanuel, Obermayer Benedikt, Mücke Michael B, Lindberg Eric L, Trnka Franziska, Memczak Sebastian, Schilling Marcel, Felkin Leanne E, Barton Paul J R, Quaife Nicholas M, Vanezis Konstantinos, Diecke Sebastian, Mukai Masaya, Mah Nancy, Oh Su-Jun, Kurtz Andreas, Schramm Christoph, Schwinge Dorothee, Sebode Marcial, Harakalova Magdalena, Asselbergs Folkert W, Vink Aryan, de Weger Roel A, Viswanathan Sivakumar, Widjaja Anissa A, Gärtner-Rommel Anna, Milting Hendrik, Dos Remedios Cris, Knosalla Christoph, Mertins Philipp, Landthaler Markus, Vingron Martin, Linke Wolfgang A, Seidman Jonathan G, Seidman Christine E, Rajewsky Nikolaus, Ohler Uwe, Cook Stuart A, Hubner Norbert 29 mei 2019, In: Cell. 178 , p. 242-260.e29

Integrative Functional Annotation of 52 Genetic Loci Influencing Myocardial Mass Identifies Candidate Regulatory Variants and Target Genes

Hemerich Daiane, Pei Jiayi, Harakalova Magdalena, van Setten Jessica, Boymans Sander, Boukens Bas J, Efimov Igor R, Michels Michelle, van der Velden Jolanda, Vink Aryan, Cheng Caroline, van der Harst Pim, Moore Jason H, Mokry Michal, Tragante Vinicius, Asselbergs Folkert W feb 2019, In: Circulation. Genomic and precision medicine. 12 , p. 76-83 8 p.

All Research Output (165)