prof. dr. ir. H.H. (Harrie) Weinans

prof. dr. ir. H.H. (Harrie) Weinans

Associate Professor
prof. dr. ir. H.H. (Harrie) Weinans
  • Department of Orthopaedics



Our stiff bones are held together by ligaments and tendons and carry the weight and transfer the large forces that are required for locomotion. Without these load bearing mechanical tissues we would look like a gelatin pudding. With aging or after trauma the delicate internal architecture of these connective tissues gets lost, which can result in e.g. cartilage damage and subsequent deterioration (osteoarthritis), loss of bone mass (osteoporosis) problematic healing of fractures or tendons. Bone and cartilage are load bearing structures and degeneration and regeneration in these tissues are continuously influenced by and adapted to the biomechanical demands. The major goal of my research is to investigate the degenerative processes in the skeletal structures and find methods to counterbalance this degeneration or even induce appropriate regeneration after the tissue is already diminished.

Harrie Weinans is minority shareholder of Uplanner BV and Replasia BV

Research Output (208)

Statistical shape model of the talus bone morphology: A comparison between impinged and nonimpinged ankles

Arbabi Saeed, Weinans Harrie, Foppen Wouter, Seevinck Peter, de Jong Pim, Sturkenboom Joran, van Hamersvelt Robbert, Foppen Wouter, Arbabi Vahid Jan 2023, In: Journal of Orthopaedic Research. 41 , p. 183-195 13 p.

Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

Roemer Frank W, Jansen Mylène, Marijnissen Anne C A, Guermazi Ali, Heiss Rafael, Maschek Susanne, Lalande Agnes, Blanco Francisco J, Berenbaum Francis, van de Stadt Lotte A, Kloppenburg Margreet, Haugen Ida K, Ladel Christoph H, Bacardit Jaume, Wisser Anna, Eckstein Felix, Lafeber Floris P J G, Weinans Harrie H, Wirth Wolfgang 17 Nov 2022, In: BMC Musculoskeletal Disorders. 23

An In Vitro Model to Test the Influence of Immune Cell Secretome on Mesenchymal Stromal Cell Osteogenic Differentiation

Khokhani Paree, Belluomo Ruggero, Croes Michiel, Gawlitta Debby, Kruyt Moyo C, Weinans Harrie 30 Jun 2022, In: Tissue engineering. Part C, Methods. 28 , p. 420-430 11 p.

Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort

van Helvoort Eefje M, Jansen Mylène P, Marijnissen Anne C A, Kloppenburg Margreet, Blanco Francisco J, Haugen Ida K, Berenbaum Francis, Bay-Jensen Anne-Christine C, Ladel Christoph, Lalande Agnes, Larkin Jonathan, Loughlin John, Mobasheri Ali, Weinans Harrie H, Widera Pawel, Bacardit Jaume, Welsing Paco M J, Lafeber Floris P J G 16 May 2022, In: Rheumatology (Oxford, England). 62 , p. 147-157 11 p.

Controlled temperature-mediated curcumin release from magneto-thermal nanocarriers to kill bone tumors

Khodaei A., Jahanmard F., Madaah Hosseini H. R., Bagheri R., Dabbagh A., Weinans H., Amin Yavari S. May 2022, In: Bioactive Materials. 11 , p. 107-117 11 p.

Correction to:Making the patient voice heard in a research consortium: experiences from an EU project (IMI-APPROACH) (Research Involvement and Engagement, (2021), 7, 1, (24), 10.1186/s40900-021-00267-0)

Taylor Jane, Dekker Sjouke, Jurg Diny, Skandsen Jon, Grossman Maureen, Marijnissen Anne Karien, Ladel Christoph, Mobasheri Ali, Larkin Jon, Weinans Harrie, Kanter-Schlifke Irene, 19 Apr 2022, In: Research involvement and engagement. 8

Sprague Dawley Rats Show More Severe Bone Loss, Osteophytosis and Inflammation Compared toWistar Han Rats in a High-Fat, High-Sucrose Diet Model of Joint Damage

Warmink Kelly, Rios Jaqueline L, van Valkengoed Devin R, Korthagen Nicoline M, Weinans Harrie 28 Mar 2022, In: International journal of molecular sciences. 23 , p. 1-10

Patient-specific 3D-printed shelf implant for the treatment of hip dysplasia tested in an experimental animal pilot in canines

Willemsen Koen, Tryfonidou Marianna A., Sakkers Ralph J.B., Castelein René M., Beukers Martijn, Seevinck Peter R., Weinans Harrie, van der Wal Bart C.H., Meij Björn P. 22 Feb 2022, In: Scientific Reports. 12 , p. 3032

Good long-term outcomes of the hip Chiari osteotomy in adolescents and adults with hip dysplasia:a systematic review

Willemsen Koen, Niemeyer Menco J.S., Harlianto Netanja I., Sadiqi Said, Seevinck Peter R., Sakkers Ralph J.B., Weinans Harrie, van der Wal Bart C.H. 4 Feb 2022, In: Acta Orthopaedica. 93 , p. 296-302 7 p.

Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

de Vor Lisanne, van Dijk Bruce, van Kessel Kok, Kavanaugh Jeffrey S., de Haas Carla, Aerts Piet C., Viveen Marco C., Boel Edwin C., Fluit Ad C., Kwiecinski Jakub M., Krijger Gerard C., Ramakers Ruud M., Beekman Freek J., Dadachova Ekaterina, Lam Marnix G. E. H., Vogely H. Charles, van der Wal Bart C. H., van Strijp Jos A. G., Horswill Alexander R., Weinans Harrie, Rooijakkers Suzan H. M. 6 Jan 2022, In: eLife. 11 , p. 1-25

All research output

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