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prof. dr. ir. H.H. (Harrie) Weinans

Associate Professor
prof. dr. ir. H.H. (Harrie) Weinans
  • Department of Orthopaedics

Biography

Biography

Our stiff bones are held together by ligaments and tendons and carry the weight and transfer the large forces that are required for locomotion. Without these load bearing mechanical tissues we would look like a gelatin pudding. With aging or after trauma the delicate internal architecture of these connective tissues gets lost, which can result in e.g. cartilage damage and subsequent deterioration (osteoarthritis), loss of bone mass (osteoporosis) problematic healing of fractures or tendons. Bone and cartilage are load bearing structures and degeneration and regeneration in these tissues are continuously influenced by and adapted to the biomechanical demands. The major goal of my research is to investigate the degenerative processes in the skeletal structures and find methods to counterbalance this degeneration or even induce appropriate regeneration after the tissue is already diminished.

 

Research Output (173)

The Effect of Postural Pelvic Dynamics on the Three-dimensional Orientation of the Acetabular Cup in THA Is Patient Specific

Snijders Thom E, Schlösser Tom P C, van Stralen Maartje, Castelein Renee M, Stevenson Rob P, Weinans Harrie, de Gast Arthur 29 sep 2020, In: Clinical Orthopaedics and Related Research. 479 , p. 561-571 11 p.

Unravelling the knee-hip-spine trilemma from the CHECK study THE RELATION BETWEEN SAGITTAL PELVIC MORPHOLOGY AND ONSET OF DEGENERATIVE KNEE, HIP, AND SPINE DISORDERS

Van Erp J. H.J., Gielis W. P., Arbabi V., De Gast A., Weinans H., Arbabi S., Öner F. C., Castelein R. M., Schlösser T. P.C. sep 2020, In: Bone and Joint Journal. 102 , p. 1261-1267 7 p.

Treating infections with ionizing radiation:a historical perspective and emerging techniques

van Dijk B, Lemans J V C, Hoogendoorn R M, Dadachova E, de Klerk J M H, Vogely H C, Weinans H, Lam M G E H, van der Wal B C H 31 jul 2020, In: Antimicrobial Resistance and Infection Control. 9

Cohort profile:The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers

van Helvoort Eefje M., van Spil Willem E., Jansen Mylène P., Welsing Paco M.J., Kloppenburg Margreet, Loef Marieke, Blanco Francisco J., Haugen Ida K., Berenbaum Francis, Bacardit Jaume, Ladel Christoph H., Loughlin John, Bay-Jensen Anne C., Mobasheri Ali, Larkin Jonathan, Boere Janneke, Weinans Harrie H., Lalande Agnes, Marijnissen Anne C.A., Lafeber Floris P.J.G. 28 jul 2020, In: BMJ Open. 10 10 p.

Long-term outcomes of the hip shelf arthroplasty in adolescents and adults with residual hip dysplasia:a systematic review

Willemsen Koen, Doelman Christiaan J, Sam Ali S Y, Seevinck Peter R, Sakkers Ralph J B, Weinans Harrie, van Der Wal Bart C H 3 jul 2020, In: Acta Orthopaedica. 91 , p. 383-389 7 p.

Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data

Widera Paweł, Welsing Paco M.J., Ladel Christoph, Loughlin John, Lafeber Floris P.F.J., Petit Dop Florence, Larkin Jonathan, Weinans Harrie, Mobasheri Ali, Bacardit Jaume 21 mei 2020, In: Scientific Reports. 10 15 p.

Radioimmunotherapy of methicillin-resistant Staphylococcus aureus in planktonic state and biofilms

van Dijk B, Allen K J H, Helal M, Vogely H C, Lam M G E H, de Klerk J M H, Weinans H, van der Wal B C H, Dadachova E 14 mei 2020, In: PLoS ONE. 15 10 p.

High-fat feeding primes the mouse knee joint to develop osteoarthritis and pathologic infrapatellar fat pad changes after surgically induced injury

Warmink Kelly, Lippinkhof-Kozijn Anne, Bobeldijk-Pastorova Ivana, Stoop R., Weinans H, Korthagen Nicoline mei 2020, In: Osteoarthritis and Cartilage. 28 , p. 593-602 10 p.

Bone regeneration in critical-sized bone defects treated with additively manufactured porous metallic biomaterials:The effects of inelastic mechanical properties

Koolen Marianne, Yavari Saber Amin, Lietaert Karel, Wauthle Ruben, Zadpoor Amir A., Weinans Harrie 24 apr 2020, In: Materials. 13 , p. 1-11

Deep learning-based MR-to-CT synthesis:The influence of varying gradient echo-based MR images as input channels

Florkow Mateusz C, Zijlstra Frank, Willemsen Koen, Maspero Matteo, van den Berg Cornelis A T, Kerkmeijer Linda G W, Castelein René M, Weinans Harrie, Viergever Max A, van Stralen Marijn, Seevinck Peter R apr 2020, In: Magnetic Resonance in Medicine. 83 , p. 1429-1441 13 p.

All research output

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