prof. dr. ir. H.H. (Harrie) Weinans Associate Professor
- ORT Research
Contact
hweinans@umcutrecht.nl
Research Programs
Biography
Our stiff bones are held together by ligaments and tendons and carry the weight and transfer the large forces that are required for locomotion. Without these load bearing mechanical tissues we would look like a gelatin pudding. With aging or after trauma the delicate internal architecture of these connective tissues gets lost, which can result in e.g. cartilage damage and subsequent deterioration (osteoarthritis), loss of bone mass (osteoporosis) problematic healing of fractures or tendons. Bone and cartilage are load bearing structures and degeneration and regeneration in these tissues are continuously influenced by and adapted to the biomechanical demands. The major goal of my research is to investigate the degenerative processes in the skeletal structures and find methods to counterbalance this degeneration or even induce appropriate regeneration after the tissue is already diminished.
Research Output (173)
Florkow Mateusz C, Zijlstra Frank, Willemsen Koen, Maspero Matteo, van den Berg Cornelis A T, Kerkmeijer Linda G W, Castelein René M, Weinans Harrie, Viergever Max A, van Stralen Marijn, Seevinck Peter R apr 2020, In: Magnetic Resonance in Medicine. 83 , p. 1429-1441 13 p.
Koolen Marianne K.E., Kruyt Moyo C., Öner Fetullah C., Schaden Wolfgang, Weinans Harrie, van der Jagt Olav P. 1 dec 2019, In: ARCHIVES OF OSTEOPOROSIS. 14 7 p.
Koolen Marianne K.E., Kruyt Moyo C., Öner Fetullah C., Schaden Wolfgang, Weinans Harrie, van der Jagt Olav P. 1 dec 2019, In: ARCHIVES OF OSTEOPOROSIS. 14 7 p.
Gielis W P, Weinans H, Welsing P M J, van Spil W E, Agricola R, Cootes T F, de Jong P A, Lindner C 8 okt 2019, In: Osteoarthritis and Cartilage. 28 , p. 62-70 9 p.
Gielis W P, Weinans H, Welsing P M J, van Spil W E, Agricola R, Cootes T F, de Jong P A, Lindner C 8 okt 2019, In: Osteoarthritis and Cartilage. 28 , p. 62-70 9 p.
Garcia João P, Longoni Alessia, Gawlitta Debby, J W P Rosenberg Antoine, Grinstaff Mark W, Töyräs Juha, Weinans Harrie, Creemers Laura B, Pouran Behdad 30 sep 2019, In: Acta Biomaterialia. 100 , p. 202-212 11 p.
Koolen M, Longoni A, van der Stok J, Van der Jagt O, Gawlitta D, Weinans H 17 sep 2019, In: European Cells & Materials. 38 , p. 94-105 12 p.
Koolen M, Longoni A, van der Stok J, Van der Jagt O, Gawlitta D, Weinans H 17 sep 2019, In: European Cells & Materials. 38 , p. 94-105 12 p.
Akhavan Behnam, Croes Michiel, Wise Steven G., Zhai Chongpu, Hung Juichien, Stewart Callum, Ionescu Mihail, Weinans Harrie, Gan Yixiang, Amin Yavari S., Bilek Marcela M.M. 1 sep 2019, In: Applied Materials Today. 16 , p. 456-473 18 p.
Rudnik-Jansen Imke, Tellegen Anna R, Pouran Behdad, Schrijver Karin, Meij Björn P, Emans Pieter J, de Gendt Erin, Thomas Rachel E, Kik Marja J L, de Visser Huub M, Weinans Harrie, Egas Annelies, van Maarseveen Erik, Woike Nina, Mihov George, Thies Jens, Tryfonidou Marianna A, Creemers Laura B 5 aug 2019, In: British Journal of Pharmacology. 176 , p. 4050-4064 15 p.