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prof. dr. E.J.H.J. (Emmanuel) Wiertz

prof. dr. E.J.H.J. (Emmanuel) Wiertz

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Research Output (73)

A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants

Pishesha Novalia, Harmand Thibault J, Rothlauf Paul W, Praest Patrique, Alexander Ryan K, van den Doel Renate, Liebeskind Mariel J, Vakaki Maria A, McCaul Nicholas, Wijne Charlotte, Verhaar Elisha, Pinney William, Heston Hailey, Bloyet Louis-Marie, Pontelli Marjorie Cornejo, Ilagan Ma Xenia G, Jan Lebbink Robert, Buchser William J, Wiertz Emmanuel J H J, Whelan Sean P J, Ploegh Hidde L 2 Nov 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118 , p. 1-10

The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I

Schuren A B C, Boer I G J, Bouma E M, Van de Weijer M L, Costa A I, Hubel P, Pichlmair A, Lebbink R J, Wiertz E J H J 2 Jan 2021, In: Molecules (Basel, Switzerland). 26

Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections

Enders Marika, Franken Lars, Philipp Marie-Sophie, Kessler Nina, Baumgart Ann-Kathrin, Eichler Melanie, Wiertz Emmanuel J H, Garbi Natalio, Kurts Christian 1 Jan 2020, In: Journal of Immunology. 204 , p. 87-100 14 p.

Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter

Wąchalska Magda, Graul Małgorzata, Praest Patrique, Luteijn Rutger D, Babnis Aleksandra W, Wiertz Emmanuel J H J, Bieńkowska-Szewczyk Krystyna, Lipińska Andrea D 7 Dec 2019, In: Cells. 8

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection

Luteijn Rutger D, van Diemen Ferdy, Blomen Vincent A, Boer Ingrid G J, Manikam Sadasivam Saravanan, van Kuppevelt Toin H, Drexler Ingo, Brummelkamp Thijn R, Lebbink Robert Jan, Wiertz Emmanuel J 1 Jul 2019, In: Journal of Virology. 93

A flow cytometry-based approach to unravel viral interference with the MHC class I antigen processing and presentation pathway

Praest Patrique, de Buhr Hendrik, Wiertz Emmanuel J.H.J. 31 May 2019, p. 187-198 12 p.

Transmembrane regions of bovine herpesvirus 1-encoded UL49.5 and glycoprotein M regulate complex maturation and ER-Golgi trafficking

Graul Malgorzata, Kisielnicka Edyta, Rychlowski Michal, Verweij Marieke C., Tobler Kurt, Ackermann Mathias, Wiertz Emmanuel J.H.J., Bieńkowska-Szewczyk Krystyna, Lipińska Andrea D. 1 Mar 2019, In: Journal of General Virology. 100 , p. 497-510 14 p.

The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins

Praest P., Luteijn R. D., Brak-Boer I. G.J., Lanfermeijer J., Hoelen H., Ijgosse L., Costa A. I., Gorham R. D., Lebbink R. J., Wiertz E. J.H.J. 4 Jun 2018, In: Molecular Immunology. 101 , p. 55-64 10 p.

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol

Luteijn Rutger David, Drexler Ingo, Smith Geoffrey L, Lebbink Robert Jan, Wiertz Emmanuel J H J Jun 2018, In: Journal of General Virology. 99 , p. 790-804 15 p.

Endocytosed soluble cowpox virus protein CPXV012 inhibits antigen cross-presentation in human monocyte-derived dendritic cells

Spel Lotte, Luteijn Rutger D., Drijfhout Jan W., Nierkens Stefan, Boes Marianne, Wiertz Emmanuel J.H. 8 Feb 2018, In: Immunology and Cell Biology. 96 , p. 137-148

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