dr. R.M. (Roelie) Wösten-van Asperen
dr. R.M. (Roelie) Wösten-van Asperen

- IC patient care
Research Programs
Biography
Biography
Roelie Wösten-van Asperen is a pediatric-intensivist at the PICU of the Wilhelmina Children’s Hospital in Utrecht. She started her fellowship in pediatric intensive care in 2002. After finalization of her fellowship, she has been a consultant pediatric intensivist in the Emma Children’s Hospital/Academic Medical Center, Amsterdam. In 2011, she defended her thesis ‘The role of the renin-angiotensin system in acute lung injury’ at the University of Amsterdam.
After almost 15 years (in January 2016), she moved from the PICU of the Emma Children’s Hospital to the PICU of the Wilhelmina Children’s Hospital in Utrecht. Together with Prof. Marry van den Heuvel of the Princess Máxima Center for Pediatric Oncology, she started a research group on pediatric cancer patients at the PICU.
She is currently chair of the PICU Oncology Kids in Europe Research group (POKER), a research consortium comprising of 21 PICU’s which are adhered to large pediatric oncological centers in 11 different countries (Austria, Belgium, Denmark, Germany, France, Italy, Poland, Spain, Switzerland, the Netherlands, and the UK). Our mission is to improve our understanding and our ability to appropriately treat these patients, thereby improving outcomes of children with cancer who are admitted to the PICU.
Education/training
1988-1993 Medical Biology, Groningen University, Groningen, The Netherlands Degree: MSc (cum laude)
1991-1995 Medicine, Groningen University, Groningen, The Netherlands. Degree: MSc (cum laude)
1995-1997 Medical Degree Groningen University, Groningen, The Netherlands. Degree: MD (cum laude)
1997-2002 Training in pediatrics, University of Leiden (1997-1999) and University of Groningen (2000-2002), The Netherlands
2002-2006 Fellowship pediatric intensive care medicine, Emma Children’s Hospital/Academic Medical Center, Amsterdam, The Netherlands
2005-2011 PhD ‘The role of the renin angiotensin system in acute lung injury’, University of Amsterdam, Amsterdam, The Netherlands
Researchline
Pediatric cancer patients at the PICU: identifying prognostic factors influencing PICU admission and outcome of pediatric cancer patients.
Side Activities
Chair of POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric & Neonatol Intensive Care).
Member of European Society of Paediatric & Neonatol Intensive Care
Fellowship and Awards
Funding as Co-PI:
2012 Academic Medical Center Graduate School Scholarship: Impact of age on the pulmonary renin-angiotensin system in acute respiratory distress syndrome (Euro 205K)
2017 Research grant supported by KiKa: Identifying the critically ill pediatric cancer patient. (Euro 590K)
Research Output (56)
Soeteman Marijn, Fiocco Marta F, Nijman Joppe, Bollen Casper W, Marcelis Maartje M, Kilsdonk Ellen, Nieuwenhuis Edward E S, Kappen Teus H, Tissing Wim J E, Wösten-van Asperen Roelie M 12 Jul 2023, In: Frontiers in oncology. 13 12 p.
Ho Antonia, Orton Richard, Tayler Rachel, Asamaphan Patawee, Herder Vanessa, Davis Chris, Tong Lily, Smollett Katherine, Manali Maria, Allan Jay, Rawlik Konrad, McDonald Sarah E., Vink Elen, Pollock Louisa, Gannon Louise, Evans Clair, McMenamin Jim, Roy Kirsty, Marsh Kimberly, Divala Titus, Holden Matthew T.G., Lockhart Michael, Yirrell David, Currie Sandra, O’Leary Maureen, Henderson David, Shepherd Samantha J., Jackson Celia, Gunson Rory, MacLean Alasdair, McInnes Neil, Bradley-Stewart Amanda, Battle Richard, Hollenbach Jill A., Henderson Paul, Odam Miranda, Chikowore Primrose, Oosthuyzen Wilna, van den Berg J. M.Merlijn, Nagelkerke Sietse, van der Flier Michiel, Tissing Wim J.E., Wösten-van Asperen Roelie M., Vastert Sebastiaan J., Vijlbrief Daniel C., Bont Louis J., Wolfs Tom F.W., Beudeker Coco R., Tempel Dennie, van Keulen Danielle, , 30 May 2023, In: Nature. 617 , p. 555-563 9 p.
Morfopoulou Sofia, Buddle Sarah, Torres Montaguth Oscar Enrique, Atkinson Laura, Guerra-Assunção José Afonso, Moradi Marjaneh Mahdi, Zennezini Chiozzi Riccardo, Storey Nathaniel, Campos Luis, Hutchinson J. Ciaran, Counsell John R., Pollara Gabriele, Roy Sunando, Venturini Cristina, Antinao Diaz Juan F., Siam Ala’a, Tappouni Luke J., Asgarian Zeinab, Ng Joanne, Hanlon Killian S., Lennon Alexander, McArdle Andrew, Czap Agata, Rosenheim Joshua, Andrade Catarina, Anderson Glenn, Lee Jack C.D., Williams Rachel, Williams Charlotte A., Tutill Helena, Nagelkerke Sietse, van der Flier Michiel, Tissing Wim J.E., Wösten-van Asperen Roelie M., Vastert Sebastiaan J., Vijlbrief Daniel C., Bont Louis J., Wolfs Tom F.W., Beudeker Coco R., Tempel Dennie, van Keulen Danielle, de Groot Ronald, van der Flier Michiel, van Aerde Koen, Heidema J., Miedema C. J., Jongerius Ilse, van den Berg J. M., Schonenberg D., Zandstra Judith, , , 18 May 2023, In: Nature. 617 , p. 564-573 10 p.
Veldhoen Esther S, van der Wal Roosmarijn, Verweij-van den Oudenrijn Laura P, Wösten-van Asperen Roelie M, Gaytant Michael A, van der Ent Cornelis K, van der Pol W Ludo, Hulzebos Erik Hj 1 Apr 2023, In: Respiratory Care. 68 , p. 531-546 16 p.
Dávila Fajardo Raquel, Raymakers-Janssen Paulien, van Grotel Martine, van Wösten-van Asperen Roelie M, Terhaard Christianus H, Lilien Marc R, van den Heuvel-Eibrink Marry M, Janssens Geert O 2023, In: Pediatric Blood & Cancer. 70
Nielsen Jeppe S.A., Agbeko Rachel, Bate Jessica, Jordan Iolanda, Dohna-Schwake Christian, Potratz Jenny, Moscatelli Andrea, Bottari Gabriella, Pappachan John, Witt Volker, Crazzolara Roman, Amigoni Angela, Mizia-Malarz Agniezka, Sánchez Martín Mariá, Willems Jef, van den Heuvel-Eibrink Marry M., Schlapbach Luregn J., Wösten-van Asperen Roelie M., 1 Dec 2022, In: Frontiers in Pediatrics. 10 10 p.
Veldhoen Esther S, Roos Johan H, Bekkema Rolien, Ludo van der Pol W, Tinnevelt Marcel H B, Verweij-van den Oudenrijn Laura P, Wösten-van Asperen Roelie M, Hulzebos Erik H J, Wijngaarde Camiel A, Kors van der Ent C 26 Apr 2022, In: Pediatric Pulmonology. 57 , p. 1618-1624 7 p.
Veldhoen Esther S, Vercoelen Femke, Ros Leandra, Verweij-van den Oudenrijn Laura P, Wösten-van Asperen Roelie M, Hulzebos Erik Hj, Bartels Bart, Gaytant Michael A, van der Ent Kors, Ludo van der Pol W 21 Apr 2022, In: Chronic Respiratory Disease. 19
Veldhoen Esther S., Wijngaarde Camiel A., Hulzebos Erik H.J., Wösten-van Asperen Roelie M., Wadman Renske I., van Eijk Ruben P.A., Asselman Fay Lynn, Stam Marloes, Otto Louise A.M., Cuppen Inge, Scheijmans Feline E.V., den Oudenrijn Laura P.Verweij van, Bartels Bart, Gaytant Michael A., van der Ent Cornelis K., van der Pol W. Ludo 21 Feb 2022, In: Orphanet Journal of Rare Diseases. 17 , p. 1-11
Steur Anouk, Raymakers-Janssen Paulien A.M.A., Kneyber Martin C.J., Dijkstra Sandra, van Woensel Job B.M., van Waardenburg Dick A., van de Ven Cornelis P., van der Steeg Alida F.W., Wijnen Marc, Lilien Marc R., de Krijger Ronald R., van Tinteren Harm, Littooij Annemieke S., Janssens Geert O., Peek Annemarie M.L., Tytgat Godelieve A.M., Mavinkurve-Groothuis Annelies M., van Grotel Martine, van den Heuvel-Eibrink Marry M., Wösten-Van Asperen Roelie M. 14 Feb 2022, In: Cancers. 14