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dr. R.M. (Roelie) Wösten-van Asperen

dr. R.M. (Roelie) Wösten-van Asperen

Associate Professor
dr. R.M. (Roelie) Wösten-van Asperen
  • IC patient care

Research Programs

Child Health

Biography

Biography

Roelie Wösten-van Asperen  is a pediatric-intensivist at the PICU of the Wilhelmina Children’s Hospital in Utrecht. She started her fellowship in pediatric intensive care in 2002. After finalization of her fellowship, she has been a consultant pediatric intensivist in the Emma Children’s Hospital/Academic Medical Center, Amsterdam. In 2011, she defended her thesis ‘The role of the renin-angiotensin system in acute lung injury’ at the University of Amsterdam.

After almost 15 years (in January 2016), she moved from the PICU of the Emma Children’s Hospital to the PICU of the Wilhelmina Children’s Hospital in Utrecht. Together with Prof. Marry van den Heuvel of the Princess Máxima Center for Pediatric Oncology, she started a research group on pediatric cancer patients at the PICU.

She is currently chair of the PICU Oncology Kids in Europe Research group (POKER), a research consortium comprising of 21 PICU’s which are adhered to large pediatric oncological centers in 11 different countries (Austria, Belgium, Denmark, Germany, France, Italy, Poland, Spain, Switzerland, the Netherlands, and the UK). Our mission is to improve our understanding and our ability to appropriately treat these patients, thereby improving outcomes of children with cancer who are admitted to the PICU. 

 

Education/training

1988-1993 Medical Biology, Groningen University, Groningen, The Netherlands Degree: MSc (cum laude)

1991-1995 Medicine, Groningen University, Groningen, The Netherlands. Degree: MSc (cum laude)

1995-1997 Medical Degree Groningen University, Groningen, The Netherlands. Degree: MD (cum laude)

1997-2002 Training in pediatrics, University of Leiden (1997-1999) and University of Groningen (2000-2002), The Netherlands

2002-2006 Fellowship pediatric intensive care medicine, Emma Children’s Hospital/Academic Medical Center, Amsterdam, The Netherlands

2005-2011 PhD ‘The role of the renin angiotensin system in acute lung injury’, University of Amsterdam, Amsterdam, The Netherlands

 

Researchline

Pediatric cancer patients at the PICU: identifying prognostic factors influencing PICU admission and outcome of pediatric cancer patients.

 

Side Activities

Chair of POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric & Neonatol Intensive Care).

Member of European Society of Paediatric & Neonatol Intensive Care

 

Fellowship and Awards

Funding as Co-PI:

2012 Academic Medical Center Graduate School Scholarship: Impact of age on the pulmonary renin-angiotensin system in acute respiratory distress syndrome (Euro 205K)

2017 Research grant supported by KiKa: Identifying the critically ill pediatric cancer patient. (Euro 590K)

Research Output (35)

Identifying the critically ill paediatric oncology patient:a study protocol for a prospective observational cohort study for validation of a modified Bedside Paediatric Early Warning System score in hospitalised paediatric oncology patients

Soeteman Marijn, Kappen Teus H, van Engelen Martine, Kilsdonk Ellen, Koomen Erik, Nieuwenhuis Edward E S, Tissing Wim J E, Fiocco Marta, van den Heuvel-Eibrink Marry, Wösten-van Asperen Roelie M 19 mei 2021, In: BMJ Open. 11 8 p.

Quality of life and psychosocial outcomes in children with severe acute asthma and their parents

Boeschoten Shelley A., Dulfer Karolijn, Boehmer Annemie L.M., Merkus Peter J.F.M., van Rosmalen Joost, de Jongste Johan C., de Hoog Matthijs, Buysse Corinne M.P., Heisterkamp Sabien, van Woensel Job, Haarman Eric, Kapitein Berber, Wösten-van Asperen Roelie, Kneyber Martin, Lemson Joris, Hartman Stan, van Waardenburg Dick, Bunker Heleen, Brouwer Carole, van Ewijk Bart, Landstra Anneke, Verwaal Mariel, Vaessen-Verberne Anja, Hammer Sanne, 1 nov 2020, In: Pediatric Pulmonology. 55 , p. 2883-2892 10 p.

Systemic hypertension after craniotomy in pediatric oncology patients

Wang Bi-Nan, Koomen Erik, Hoving Eelco W, Wösten-van Asperen RM, Nijman Joppe okt 2020,

Risk factors for intensive care admission in children with severe acute asthma in the Netherlands:a prospective multicentre study

Boeschoten Shelley A, Boehmer Annemie L, Merkus Peter J, van Rosmalen Joost, de Jongste Johan C, Fraaij Pieter L A, Molenkamp Richard, Heisterkamp Sabien G, van Woensel Job B, Kapitein Berber, Haarman Eric G, Wösten-van Asperen Roelie M, Kneyber Martin C, Lemson Joris, Hartman Stan, van Waardenburg Dick A, Bunker-Wiersma Heleen E, Brouwer Carole N, van Ewijk Bart E, Landstra Anneke M, Verwaal Mariel, Vaessen-Verberne Anja A, Hammer Sanne, Buysse Corinne M, de Hoog Matthijs jul 2020, In: BMJ open [E]. 6

Relative hyperventilation in non-ventilated patients with spinal muscular atrophy

Veldhoen Esther S, Wijngaarde Camiel A, Verweij-van den Oudenrijn Laura P, Asselman Fay-Lynn, Wösten-van Asperen Roelie M, Hulzebos Erik H J, van der Ent Kors, Cuppen Inge, Gaytant Michael A, van Eijk Ruben P A, van der Pol W Ludo 25 jun 2020, In: The European respiratory journal. 56

Natural history of lung function in spinal muscular atrophy

Wijngaarde Camiel A., Veldhoen Esther S., van Eijk Ruben P.A., Stam Marloes, Otto Louise A.M., Asselman Fay Lynn, Wösten-van Asperen Roelie M., Hulzebos Erik H.J., Verweij-van den Oudenrijn Laura P., Bartels Bart, Cuppen Inge, Wadman Renske I., van den Berg Leonard H., van der Ent Cornelis K., van der Pol W. Ludo 10 apr 2020, In: Orphanet Journal of Rare Diseases. 15 11 p.

Effect of mechanical insufflation-exsufflation in children with neuromuscular weakness

Veldhoen Esther S., Verweij-van den Oudenrijn Laura P., Ros Leandra A., Hulzebos Erik H., Papazova Diana A., van der Ent Cornelis K., van der Pol Ludo W., Nijman Joppe, Wösten-van Asperen Roelie M. 1 feb 2020, In: Pediatric Pulmonology. 55 , p. 510-513 4 p.

PICU Admission Rates in Pediatric Cancer and Hematopoietic Stem Cell Transplant Patients Receiving High-flow Nasal Cannula Oxygen Therapy on the General Ward

Van Dorst Mila, Van Gestel Josephus P.J., Van Grotel Martine, Versluijs Birgitta, Van Den Heuvel-Eibrink Marry M., Nijman Joppe, Wösten-Van Asperen Roelie M. 1 nov 2019, In: Journal of Pediatric Hematology/oncology. 42 , p. e1-e6

Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response

Schouten Laura R A, Bos Lieuwe D J, Serpa Neto A, van Vught Lonneke A, Wiewel Maryse A, Hoogendijk Arie J, Bonten Marc J M, Cremer Olaf L, Horn Janneke, van der Poll Tom, Schultz Marcus J, Wösten-van Asperen Roelie M, 29 okt 2019, In: Intensive Care Medicine Experimental. 7 10 p.

Short-term effect of surgery for non-idiopathic scoliosis on pulmonary function

Veldhoen Esther, De Vries Anneloes, Tersmette Joyce, Verweij-Van den Oudenrijn Laura, Hulzebos Erik, Wosten-Van Asperen Roelie, Van der Ent Kors 28 sep 2019, In: European Respiratory Journal. 54

All research output

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