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drs. J.R. (Janneke) Zinkstok

drs. J.R. (Janneke) Zinkstok

Assistant Professor - medical
drs. J.R. (Janneke) Zinkstok
  • Psychiatry

Biography

Biography

Dr. Janneke Zinkstok trained as a Medical Doctor and subsequently as a Psychiatrist in Amsterdam, the Netherlands, and completed a PhD in Psychiatric Genetics (University of Amsterdam). She worked as a Clinical Research Fellow in the Institute of Psychiatry, King’s College London, where she studied brain structure in Autism Spectrum Disorders, and specialized in developmental disorders in adults at the Maudsley Hospital. She is now a Psychiatrist at the Department of Psychiatry at the UMC Utrecht, The Netherlands. Her clinical and research interests include the neurobiology of brain development and psychiatric disorders especially neurodevelopmental disorders (ADHD and autism) and psychosis, and 22q11.2 deletion syndrome.

Key publications

  1. Zinkstok, J, Boot, E, Bassett, AS, Hiroi, N, Butcher, NJ, Vingerhoets, C, Vorstman, JAS, & van Amelsvoort, TAMJ. The 22q11.2 deletion syndrome from a neurobiological perspective. 2019, in press Lancet Psychiatry.

  2. Boer J, Boot E,  van Gils L, van Amelsvoort T, Zinkstok J.  Adverse effects of antipsychotic medication in patients with 22q11.2 deletion syndrome: A systematic review. in press American Journal of Medical Genetics Part A.
  3. Boer J, Vingerhoets C, Hirdes M, McAlonan GM, Amelsvoort T, Zinkstok J. Efficacy and tolerability of riluzole in psychiatric disorders: a systematic review and preliminary meta-analysis. Psychiatry Research 2019 Aug; 278:294-302.
  4. Ajram L, Horder J, Mendez M, Galanopoulos A, Brennan L, Wichers R, Robertson D, Murphy C, Zinkstok J, Ivin G, Heasman M, Meek D, Tricklebank M, Barker G, Lythgoe D, Edden R, Williams SC, Murphy D, McAlonan G. Shifting prefrontal Excitation-Inhibition balance and functional connectivity in Autism Spectrum Disorder. Translational Psychiatry 2017 May 23;7(5):e1137.
  5. Wilson CE, Murphy CM, McAlonan G, Robertson DM, Spain D, Hayward H, Woodhouse E, Deeley PQ, Gillan N, Ohlsen JC, Zinkstok J, Stoencheva V, Faulkner J, Yildiran H, Bell V, Hammond N, Craig MC, Murphy DG. Does sex influence the diagnostic evaluation of autism spectrum disorder in adults? Autism 2016 Oct;20(7):808-19.
  6. Russell AJ, Murphy CM, Wilson E, Gillan N, Brown C, Robertson DM, Craig MC, Deeley Q, Zinkstok J, Johnston K, McAlonan GM, Spain D, Murphy DG. The mental health of individuals referred for assessment of autism spectrum disorder in adulthood: A clinic report. Autism 2015 Jul;20(5):623-7.
  7. Deoni S & Zinkstok J [joint first authors], Daly E, Johnston P, Ecker C, AIMS Consortium, Murphy D.  Is brain myelination altered in autism? An in vivo MRI study. Psychological Medicine 2015, 45(4):795-805.
  8. Wilson C, Gillan N, Spain D, Robertson D, Roberts G, Murphy CM, Maltezos S, Zinkstok J, Johnston K, Dardani C, Ohlsen C, Deeley P, Craig M, Mendez M, Happé F, Murphy D.  Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic. J Autism Dev Disord 2013, 43(11):2515-25.
  9. Raux G, Bumsel E, Hecketsweiler B, van Amelsvoort T, Zinkstok J, Manouvrier-Hanu S, Fantini C, Breviere GM, Di Rosa G, Pustorino G, Vogels A, Swillen A, Legallic S, Bou J, Opolczynski G, Drouin-Garraud V, Lemarchand M, Philip N, Gerard-Desplanches A, Carlier M, Philippe A, Nolen MC, Heron D, Sarda P, Lacombe D, Coizet C, Alembik Y, Layet V, Afenjar A, Hannequin D, Demily C, Petit M, Thibaut F, Frebourg T, Campion D. Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndrome. Human Molecular Genetics 2007, 1;16(1):83-91.
  10. Zinkstok J, van Amelsvoort T. Neuropsychological profile and neuroimaging in patients with 22q11.2 Deletion Syndrome: a review. Child Neuropsychology 2005, 1: 21-37.

Research Output (49)

Vitamin D status in children with a psychiatric diagnosis, autism spectrum disorders, or internalizing disorders

Muskens Jet, Klip Helen, Zinkstok Janneke R., van Dongen-Boomsma Martine, Staal Wouter G. 14 Sep 2022, In: Frontiers in Psychiatry. 13

Untargeted metabolic analysis in dried blood spots reveals metabolic signature in 22q11.2 deletion syndrome

Korteling Dorinde, Boks Marco P, Fiksinski Ania M, van Hoek Ilja N, Vorstman Jacob A S, Verhoeven-Duif Nanda M, Jans Judith J M, Zinkstok Janneke R 9 Mar 2022, In: Translational Psychiatry. 12 , p. 1-7

Komt een mens bij de psychiater; op weg naar sekse- en gendersensitieve ggz

van Amelsvoort T. A.M.J., Zinkstok J. R. 2022, In: Tijdschrift voor Psychiatrie. 64 , p. 497-499 3 p.

Leidraad genetisch testen in de psychiatrie

van der Horst M. Z., Aalfs C. M., Vorstman J. A.S., Luykx J. J., Zinkstok J. R. 2022, In: Tijdschrift voor Psychiatrie. 64 , p. 278-285 8 p.

Genetisch risico van psychiatrische ziekten:wat weten we en hoe communiceren we dat?

Zinkstok J. R., van der Horst M. Z., Wouters R. P.H., Aalfs C. M., Luykx J. J. 2022, In: Tijdschrift voor Psychiatrie. 64 , p. 266-272 7 p.

Psychiatrie en genetica:de lange weg van laboratorium naar spreekkamer

Van Assche E., Van de Woestyne K., van Elburg A. A., Birkenhäger T. K., Luykx J. J., Zinkstok J. R. 2022, In: Tijdschrift voor Psychiatrie. 64 , p. 245-247 3 p.

Transcriptomic profiling of whole blood in 22q11.2 reciprocal copy number variants reveals that cell proportion highly impacts gene expression

Lin Amy, Forsyth Jennifer K, Hoftman Gil D, Kushan-Wells Leila, Jalbrzikowski Maria, Dokuru Deepika, Coppola Giovanni, Fiksinski Ania, Zinkstok Janneke, Vorstman Jacob, Nachun Daniel, Bearden Carrie E Dec 2021, In: Brain, behavior, & immunity - health. 18 , p. 1-13

Methylphenidate for attention-deficit/hyperactivity disorder in patients with Smith–Magenis syndrome:protocol for a series of N-of-1 trials

Müller A. R., Zinkstok J. R., Rommelse N. N.J., van de Ven P. M., Roes K. C.B., Wijburg F. A., de Rooij-Askes E., Linders C., Boot E., van Eeghen A. M. Dec 2021, In: Orphanet Journal of Rare Diseases. 16 , p. 1-9

UNTARGETED METABOLIC PROFILING IN DRIED BLOOD SPOTS REVEALS METABOLIC FINGERPRINT FOR 22Q11.2 DELETION SYNDROME

Zinkstok Janneke, Korteling Dorinde, Fiksinski Ania, Jans Judith, Verhoeven Nanda, Boks Marco Oct 2021, In: European Neuropsychopharmacology. 51 , p. E130-E130

Parkinsonism in individuals with genetic neurodevelopmental disorders: A systematic review

Scheibler E., Kuijf M., Koning T., Zinkstok J., Muller A., Amelsvoort T., Eeghen A., Boot E. Sep 2021, In: Movement Disorders. 36 , p. S320-S321

All research output

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