dr. M.G.P. (Mira) Zuidgeest

dr. M.G.P. (Mira) Zuidgeest

Associate Professor
dr. M.G.P. (Mira) Zuidgeest
  • Julius Center, dept. Global Public Health & Bioethics

Research Programs

Circulatory Health



Mira G.P. Zuidgeest, PhD PharmD, Epidemiologist works as associate professor at the Julius Center for Health Sciences and Primary Care, department Epidemiology and Global Health. Trained both as a pharmacist and epidemiologist and with a PhD in pharmacoepidemiology in the field of paediatric asthma, her current work focuses on clinical trial innovation, both methodological and operational.

As core member of the GetReal Institute, her work focusses on randomised clinical trials integrated into routine clinical practice (also called pragmatic trials) and the methodological and operational consequences of introducing real world elements in trial design, for which she led the development of a decision-support tool (

As overall scientific lead and WP3 lead for the IMI Trials@Home project (, she looks into the possibilities of centring trials around patients rather than clinical sites by use of innovative technologies (so called Decentralised Clinical Trials).

Research Output (29)

Direct-to-participant investigational medicinal product supply in clinical trials in Europe:Exploring the experiences of sponsors, site staff and couriers

de Jong Amos J., Santa-Ana-Tellez Yared, Zuidgeest Mira G.P., Grupstra Renske J., Jami Fatemeh, de Boer Anthonius, Gardarsdottir Helga, 12 Jul 2023, In: British Journal of Clinical Pharmacology. 89 , p. 3512-3522 11 p.

Validation of the GetReal Trial Tool - Facilitating discussion and understanding more pragmatic design choices and their implications

Boateng Daniel, Kumke Thomas, Vernooij Robin, Goetz Iris, Meinecke Anna Katharina, Steenhuis Charlotte, Grobbee Diederick, Zuidgeest Mira GP 15 Dec 2022, In: Contemporary Clinical Trials. 125

A cross-sectional survey on the early impact of COVID-19 on the uptake of decentralised trial methods in the conduct of clinical trials

Suman Arnela, van Es Jasmijn, Gardarsdottir Helga, Grobbee Diederick E., Hawkins Kimberly, Heath Megan A., Mackenzie Isla S., van Thiel Ghislaine, Zuidgeest Mira G.P., Dec 2022, In: Trials. 23

Which decentralised trial activities are reported in clinical trial protocols of drug trials initiated in 2019-2020? A cross-sectional study in

de Jong Amos J., Grupstra Renske J., Santa-Ana-Tellez Yared, Zuidgeest Mira G.P., de Boer Anthonius, Gardarsdottir Helga, 29 Aug 2022, In: BMJ Open. 12

Ethics review of decentralized clinical trials (DCTs):Results of a mock ethics review

van Rijssel Tessa I, de Jong Amos J, Santa-Ana-Tellez Yared, Boeckhout Martin, Zuidgeest Mira G P, van Thiel Ghislaine J M W, 20 Jul 2022, In: Drug Discovery Today. 27 , p. 1-6

Opportunities and Challenges for Decentralized Clinical Trials:European Regulators' Perspective

de Jong Amos J, van Rijssel Tessa I, Zuidgeest Mira G P, van Thiel Ghislaine J M W, Askin Scott, Fons-Martínez Jaime, De Smedt Tim, de Boer Anthonius, Santa-Ana-Tellez Yared, Gardarsdottir Helga, 30 Apr 2022, In: Clinical Pharmacology and Therapeutics. 112 , p. 344-352 9 p.

The GetReal Trial Tool:design, assess and discuss clinical drug trials in light of Real World Evidence generation

Zuidgeest Mira G.P., Goetz Iris, Meinecke Anna Katharina, Boateng Daniel, Irving Elaine A., van Thiel Ghislaine J.M., Welsing Paco M.J., Oude-Rengerink Katrien, Grobbee Diederick E., 17 Dec 2021, In: Journal of Clinical Epidemiology. 149 , p. 244-253 10 p.

COVID-19 and the Emerging Regulatory Guidance for Ongoing Clinical Trials in the European Union

de Jong Amos Jochanan, Santa-Ana-Tellez Yared, van Thiel Ghislaine José Madeleine Wilhelmien, Zuidgeest Mira Gerta Petra, Siiskonen Satu Johanna, Mistry Dinesh, de Boer Anthonius, Gardarsdottir Helga, 2021, In: Clinical Pharmacology and Therapeutics. 109 , p. 1517-1527 11 p.


Steenhuis C., Meinecke A. K., Goetz I, Zuidgeest M. Nov 2019, In: Value in Health. 22 , p. S729-S729

Women in Translational Medicine: Tools to Break the Glass Ceiling

Bots Sophie H., Zuidgeest Mira G. P., Gohar Aisha, Eikendal Anouk L. M., Petrelli Alessandra, van Os-Medendorp Harmieke, van der Schaaf Marieke F., van Sorge Nina M., van Wijk Myriam, Middendorp Sabine, Speksnijder Caroline M., Klipstein-Grobusch Kerstin, Seyfert-Margolis Vicky, Mollema Esther, van Wijk Femke, den Ruijter Hester M. 2018, In: Frontiers in medicine. 5

All research output

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