dr. M.G.P. (Mira) Zuidgeest

dr. M.G.P. (Mira) Zuidgeest

Associate Professor
dr. M.G.P. (Mira) Zuidgeest
  • Department of Epidemiology
  • Julius Center Research Program Methodology

Research Programs

Circulatory Health



Mira G.P. Zuidgeest, PhD PharmD, Epidemiologist works as associate professor at the Julius Center for Health Sciences and Primary Care, department Epidemiology and Global Health. Trained both as a pharmacist and epidemiologist and with a PhD in pharmacoepidemiology in the field of paediatric asthma, her current work focuses on clinical trial innovation, both methodological and operational.

As core member of the GetReal Institute, her work focusses on randomised clinical trials integrated into routine clinical practice (also called pragmatic trials) and the methodological and operational consequences of introducing real world elements in trial design, for which she led the development of a decision-support tool (

As overall scientific lead and WP3 lead for the IMI Trials@Home project (, she looks into the possibilities of centring trials around patients rather than clinical sites by use of innovative technologies (so called Decentralised Clinical Trials).

Research Output (23)

Ethics review of decentralized clinical trials (DCTs):Results of a mock ethics review

van Rijssel Tessa I, de Jong Amos J, Santa-Ana-Tellez Yared, Boeckhout Martin, Zuidgeest Mira G P, van Thiel Ghislaine J M W, 20 Jul 2022, In: Drug Discovery Today. 27 , p. 1-6

COVID-19 and the Emerging Regulatory Guidance for Ongoing Clinical Trials in the European Union

de Jong Amos Jochanan, Santa-Ana-Tellez Yared, van Thiel Ghislaine José Madeleine Wilhelmien, Zuidgeest Mira Gerta Petra, Siiskonen Satu Johanna, Mistry Dinesh, de Boer Anthonius, Gardarsdottir Helga, 2021, In: Clinical Pharmacology and Therapeutics. 109 , p. 1517-1527 11 p.


Steenhuis C., Meinecke A. K., Goetz I, Zuidgeest M. Nov 2019, In: Value in Health. 22 , p. S729-S729

Women in Translational Medicine: Tools to Break the Glass Ceiling

Bots Sophie H., Zuidgeest Mira G. P., Gohar Aisha, Eikendal Anouk L. M., Petrelli Alessandra, van Os-Medendorp Harmieke, van der Schaaf Marieke F., van Sorge Nina M., van Wijk Myriam, Middendorp Sabine, Speksnijder Caroline M., Klipstein-Grobusch Kerstin, Seyfert-Margolis Vicky, Mollema Esther, van Wijk Femke, den Ruijter Hester M. 2018, In: Frontiers in medicine. 5

Series: Pragmatic trials and real world evidence:Paper 8 Data collection and management Data collection in Pragmatic Trials

Meinecke Anna Katharina, Welsing Paco, Kafatos George, Burke Des, Trelle Sven, Kubin Maria, Nachbaur Gaelle, Egger Matthias, Zuidgeest Mira, 14 Jul 2017, In: Journal of Clinical Epidemiology. 91 , p. 13-22 10 p.

Series: Pragmatic trials and real world evidence:Paper 5. Usual care and real life comparators.

Zuidgeest Mira G, Welsing Paco, van Thiel Ghislaine, Ciaglia Antonio, Alfonso-Cristancho Rafael, Eckert Laurent, Eijkemans Marinus J C, Egger Matthias, 7 Jul 2017, In: Journal of Clinical Epidemiology. 90 , p. 92-98 7 p.

PRECIS-2 in perspective:what is next for pragmatic trials?

Zuidgeest Mira G, Goetz Iris, Grobbee Diederick E, Apr 2017, In: Journal of Clinical Epidemiology. 84 , p. 22-24 3 p.

The social value of pragmatic trials

Kalkman Shona, Van Thiel Ghislaine, Van Der Graaf Rieke, Zuidgeest Mira, Goetz Iris, Grobbee Diederick, Van Delden Johannes 1 Feb 2017, In: Bioethics. 31 , p. 136-143 8 p.

Series: Pragmatic trials and real world evidence:Paper 1. Introduction

Zuidgeest Mira G P, Goetz Iris, Groenwold Rolf H H, Irving Elaine, van Thiel Ghislaine J M W, Grobbee Diederick E, 2017, In: Journal of Clinical Epidemiology. 88 , p. 7-13 7 p.

All research output

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