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dr. ir. J.J.M. (Jaco J.M.) Zwanenburg

dr. ir. J.J.M. (Jaco J.M.) Zwanenburg

Associate Professor
dr. ir. J.J.M. (Jaco J.M.) Zwanenburg

Biography

Biography

Jaco Zwanenburg studied Applied Physics at the Delft University of Technology (1995 - 2001). He concluded his study with a research project in MRI at Philips Medical Systems, Best. In this project he developed a patented method to use sensitivity encoding from multiple receive coils to reduce artifacts in the reconstructed image caused by the field inhomogeneity and gradient non-linearity of the MR system.

From 2001 until 2005, he did his PhD research at the VU University Medical Center, Amsterdam, with a project on MRI and myocardial tagging to study the dyssynchrony in the mechanical contraction of the human heart.

His current research focus is on designing and implementing new MRI techniques at ultra-high field strength (7T), to stimulate further understanding of cerebrovascular diseases. Exploiting the rich sources of endogenous MRI contrast, he developed imaging techniques for angiography, venography, brain anatomy, and microscopic brain lesions resulting from small vessel disease, including microbleeds and microinfarcts. Furthermore, he has developed imaging strategies for imaging post mortem specimens at high resolution, to bridge the gap between histology and in-vivo imaging in patients.

Side Activities

None

Fellowship and Awards

ERC starting grant 'Towards understanding cerebral small vessel disease: Innovative, MRI-based, functional markers to discover the terra incognita between large vessels and macroscopic brain lesions (SmallVesselMRI)' (2013, ERC grant agreement n°337333).

Research Output (131)

Double delay alternating with nutation for tailored excitation facilitates banding-free isotropic high-resolution intracranial vessel wall imaging

Coolen Bram F, Schoormans Jasper, Gilbert Guillaume, Kooreman Ernst S, de Winter Naomi, Viessmann Olivia, Zwanenburg Jaco J M, Majoie Charles B.L.M., Strijkers Gustav J, Nederveen Aart J, Siero Jeroen C W 2 jun 2021, In: NMR in Biomedicine. 34 10 p.

Velocity and Pulsatility Measures in the Perforating Arteries of the Basal Ganglia at 3T MRI in Reference to 7T MRI

Arts Tine, Meijs Timion A, Grotenhuis Heynric, Voskuil Michiel, Siero Jeroen, Biessels Geert Jan, Zwanenburg Jaco 26 apr 2021, In: Frontiers in Neuroscience. 15 10 p.

Strain Tensor Imaging:Cardiac-induced brain tissue deformation in humans quantified with high-field MRI

Sloots Jacob-Jan, Biessels Geert Jan, de Luca Alberto, Zwanenburg Jaco J M 17 apr 2021, In: NeuroImage. 236 , p. 1-14

Subvoxel vessel wall thickness measurements of the intracranial arteries using a convolutional neural network

van Hespen Kees M, Zwanenburg Jaco J M, Hendrikse Jeroen, Kuijf Hugo J jan 2021, In: Medical Image Analysis. 67 , p. 1-10

Arterial Remodeling of the Intracranial Arteries in Patients With Hypertension and Controls:A Postmortem Study

van Hespen Kees M, Mackaaij Claire, Waas Ingeborg S E, de Bree Marloes P, Zwanenburg Jaco J M, Kuijf Hugo J, Daemen Mat J A P, Hendrikse Jeroen, Hermkens Dorien M A jan 2021, In: Hypertension (Dallas, Tex. : 1979). 77 , p. 135-146 12 p.

Automated Assessment of Cerebral Arterial Perforator Function on 7T MRI

Arts Tine, Siero Jeroen C W, Biessels Geert Jan, Zwanenburg Jaco J M 18 aug 2020, In: Journal of Magnetic Resonance Imaging. 53 , p. 234-241 8 p.

Velocity Pulsatility and Arterial Distensibility Along the Internal Carotid Artery

van Tuijl Rick J., Ruigrok Ynte M., Velthuis Birgitta K., van der Schaaf Irene C., Rinkel Gabriël J.E., Zwanenburg Jaco J.M. 18 aug 2020, In: Journal of the American Heart Association. 9 , p. e016883 11 p.

Cardiac and respiration-induced brain deformations in humans quantified with high-field MRI

Sloots Jacob-Jan, Biessels Geert Jan, Zwanenburg Jaco J M 15 apr 2020, In: NeuroImage. 210 11 p.

Inter-patient variations in flow boundary conditions at middle cerebral artery from 7T PC-MRI and influence on Computational Fluid Dynamics of intracranial aneurysms

Rajabzadeh-Oghaz Hamidreza, van Ooij Pim, Veeturi Sricharan S., Tutino Vincent M., Zwanenburg Jaco JM, Meng Hui 15 apr 2020, In: Computers in Biology and Medicine. 120 , p. 103759 9 p.

Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease:A 7 Tesla MRI study

Bouvy Willem H, van Veluw Susanne J, Kuijf Hugo J, Zwanenburg Jaco Jm, Kappelle Jaap L, Luijten Peter R, Koek Huiberdina L, Geerlings Mirjam I, Biessels Geert J, 1 apr 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40 , p. 739-746 8 p.

All research output

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