dr. ir. J.J.M. (Jaco J.M.) Zwanenburg

dr. ir. J.J.M. (Jaco J.M.) Zwanenburg

Associate Professor
dr. ir. J.J.M. (Jaco J.M.) Zwanenburg



Jaco Zwanenburg studied Applied Physics at the Delft University of Technology (1995 - 2001). He concluded his study with a research project in MRI at Philips Medical Systems, Best. In this project he developed a patented method to use sensitivity encoding from multiple receive coils to reduce artifacts in the reconstructed image caused by the field inhomogeneity and gradient non-linearity of the MR system.

From 2001 until 2005, he did his PhD research at the VU University Medical Center, Amsterdam, with a project on MRI and myocardial tagging to study the dyssynchrony in the mechanical contraction of the human heart.

His current research focus is on designing and implementing new MRI techniques at ultra-high field strength (7T), to stimulate further understanding of cerebrovascular diseases. Exploiting the rich sources of endogenous MRI contrast, he developed imaging techniques for angiography, venography, brain anatomy, and microscopic brain lesions resulting from small vessel disease, including microbleeds and microinfarcts. Furthermore, he has developed imaging strategies for imaging post mortem specimens at high resolution, to bridge the gap between histology and in-vivo imaging in patients.

Side Activities


Fellowship and Awards

ERC starting grant 'Towards understanding cerebral small vessel disease: Innovative, MRI-based, functional markers to discover the terra incognita between large vessels and macroscopic brain lesions (SmallVesselMRI)' (2013, ERC grant agreement n°337333).

Research Output (134)

Does the Internal Carotid Artery Attenuate Blood-Flow Pulsatility in Small Vessel Disease?:A 7 T 4D-Flow MRI Study

van Tuijl Rick J, Ruigrok Ynte M, Geurts Lennart J, van der Schaaf Irene C, Biessels Geert Jan, Rinkel Gabriël J E, Velthuis Birgitta K, Zwanenburg Jaco J M 2022, In: Journal of Magnetic Resonance Imaging.

Detecting low blood concentrations in joints using T1 and T2 mapping at 1.5, 3, and 7 T:an in vitro study

van Leeuwen Flora H P, Lena Beatrice, Zwanenburg Jaco J M, van Vulpen Lize F D, Bartels Lambertus W, Fischer Kathelijn, Nap Frank J, de Jong Pim A, Bos Clemens, Foppen Wouter 2 dec 2021, In: European radiology experimental. 5

Pulsatility attenuation along the carotid siphon in pseudoxanthoma elasticum

Bartstra J. W., van Tuijl R. J., de Jong P. A., Mali W. P.T.M., van der Schaaf I. C., Ruigrok Y. M., Rinkel G. J.E., Velthuis B. K., Spiering W., Zwanenburg J. J.M. 1 nov 2021, In: American Journal of Neuroradiology. 42 , p. 2030-2033 4 p.

Double delay alternating with nutation for tailored excitation facilitates banding-free isotropic high-resolution intracranial vessel wall imaging

Coolen Bram F, Schoormans Jasper, Gilbert Guillaume, Kooreman Ernst S, de Winter Naomi, Viessmann Olivia, Zwanenburg Jaco J M, Majoie Charles B.L.M., Strijkers Gustav J, Nederveen Aart J, Siero Jeroen C W 2 jun 2021, In: NMR in Biomedicine. 34 10 p.

Velocity and Pulsatility Measures in the Perforating Arteries of the Basal Ganglia at 3T MRI in Reference to 7T MRI

Arts Tine, Meijs Timion A, Grotenhuis Heynric, Voskuil Michiel, Siero Jeroen, Biessels Geert Jan, Zwanenburg Jaco 26 apr 2021, In: Frontiers in Neuroscience. 15 10 p.

Strain Tensor Imaging:Cardiac-induced brain tissue deformation in humans quantified with high-field MRI

Sloots Jacob-Jan, Biessels Geert Jan, de Luca Alberto, Zwanenburg Jaco J M 18 apr 2021, In: NeuroImage. 236 , p. 1-14

Subvoxel vessel wall thickness measurements of the intracranial arteries using a convolutional neural network

van Hespen Kees M, Zwanenburg Jaco J M, Hendrikse Jeroen, Kuijf Hugo J jan 2021, In: Medical Image Analysis. 67 , p. 1-10

Arterial Remodeling of the Intracranial Arteries in Patients With Hypertension and Controls:A Postmortem Study

van Hespen Kees M, Mackaaij Claire, Waas Ingeborg S E, de Bree Marloes P, Zwanenburg Jaco J M, Kuijf Hugo J, Daemen Mat J A P, Hendrikse Jeroen, Hermkens Dorien M A jan 2021, In: Hypertension (Dallas, Tex. : 1979). 77 , p. 135-146 12 p.

Automated Assessment of Cerebral Arterial Perforator Function on 7T MRI

Arts Tine, Siero Jeroen C W, Biessels Geert Jan, Zwanenburg Jaco J M 18 aug 2020, In: Journal of Magnetic Resonance Imaging. 53 , p. 234-241 8 p.

Velocity Pulsatility and Arterial Distensibility Along the Internal Carotid Artery

van Tuijl Rick J., Ruigrok Ynte M., Velthuis Birgitta K., van der Schaaf Irene C., Rinkel Gabriël J.E., Zwanenburg Jaco J.M. 18 aug 2020, In: Journal of the American Heart Association. 9 , p. e016883 11 p.

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht





Practical maakt gebruik van cookies

Deze website maakt gebruik van cookies Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Wij plaatsen zelf ook cookies om onze site te verbeteren.

Lees meer over het cookiebeleid

Akkoord Nee, liever niet