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dr. G.J.T. Zwartkruis

dr. G.J.T. Zwartkruis

Associate Professor

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Research Output (55)

Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

Gloerich M., Ponsioen B., Vliem M.J., Zhang Z.C., Zhao C., Kooistra M.R.H., Price L.S., Ritsma L., Zwartkruis G.J.T., Rehmann H., Jalink K., Bos J.L. 2010, In: Molecular and Cellular Biology. 30 , p. 5431-5431 1 p.

Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK

Eijkelkamp N., Wang H., Garza Carbajal A., Willemen H.L.D.M., Zwartkruis G.J.T., Wood J.N., Dantzer R., Kelley K.W., Heijnen C.J., Kavelaars A.M.A.A. 2010, In: Journal of Neuroscience. 30 , p. 12806-12815 10 p.

A mercenary among the RAs-like GTPases.

Frische E.W., Zwartkruis G.J.T. 2010, In: Developmental Biology. 340 , p. 1-9 9 p.

Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity.

Zemojtel T, Duchniewicz M, Zhang Z.C., Paluch T., Luz H., Penzkofer T., Scheele J.S., Zwartkruis G.J.T. 2010, In: BMC Evolutionary Biology. 10 , p. 55 1 p.

Cell-cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

Pannekoek W., Kooistra M.R.H., Zwartkruis G.J.T., Bos J.L. 2009, In: Biochimica et Biophysica Acta-Biomembranes. 1788 , p. 790-796 7 p.

AGC kinases regulate phosphorylation and activation of eukaryotic translation initiation factor 4B

van Gorp A.G.M., van der Vos K.E., Brenkman A.B., Bremer A., van den Broek N.J.F., Zwartkruis F., Hershey J.W.B., Burgering B.M.T., Calkhoven C.F., Coffer P.J 2009, In: Oncogene. 28 , p. 95-106 12 p.

Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells

Geest C.R., Zwartkruis G.J.T., Vellenga E., Coffer P.J, Buitenhuis M. 2009, In: Haematologica. 94 , p. 901-910 10 p.

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

Sun Y., Fang Y., Yoon M.S., Zhang Z.C., Roccio M., Zwartkruis G.J.T., Armstrong M., Brown H.A., Chen J. 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105 , p. 8286-8291 6 p.

Biochemical characterisation of TCTP questions its function as a guanine nucleotide exchange factor for Rheb.

Rehmann H., Bruning M., Berghaus C., Schwarten M., Kohler K., Stocker H., Stoll R., Zwartkruis G.J.T., Wittinghofer A. 2008, In: FEBS letters. 582 , p. 3005-3010 6 p.

RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans

Frische E.W., Pellis - van Berkel W., van Haaften G.W., Cuppen E.P.J.G., Plasterk R.H.A., Tijsterman M., Bos J.L., Zwartkruis G.J.T. 2007, In: EMBO Journal. 26 , p. 5083-5092 10 p.

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