Severe inflammatory disorders
The Child Health Program has a strong interest in inflammatory disorders of the airways, joints and the gut. Both genetic and environmental factors play a role in the development of uncontrolled chronic inflammation with subsequently serious disability and loss of quality of life. Our efforts are to increase our understanding of how environmental factors interact with genetically determined immune- and metabolic responses. This knowledge can help to develop novel preventive and therapeutic interventions and ultimately decrease the burden of disease in children and their families.
Juvenile Idiopathic Arthritis
The Center aims to understand the pathogenesis of autoimmune disorders and to translate these findings into novel concepts and improved therapeutic strategies.
The Cystic Fibrosis Center Utrecht has a leading role in Europe in developing and implementing innovative therapies at a personalized level.
Recurrent Respiratory Infections
Severe and respiratory tract infections early in life with e.g. Respiratory Syncytial Virus can have sequelae into adulthood.