dr. H. (Hilgo) Bruining Associate Professor - medical
Hilgo Bruining was trained as a pediatrician and a child and adolescent psychiatrist. He received his PhD in 2011 entitled "Genetic dissection of behavioral phenotypes". Since 2011 he is a researcher en member of clinical staff at the department of Psychiatry of the Brain Center Rudolf Magnus. He is the initiator and PI of the clinical and research care program focused on the diagnosis and treament of sensory processing abnormalities in neurodevelopmental disorders. The main focus of the program is to establish an EEG based descision support system to guide rational treatment development. In addition, he collaborates on preclinical research programs to enhance translation of animal model findings to clinical studies and practice.
Sensory Processing; Neurodevelopmental disorders; CNS inhibition;Autism Spectrum Disorder;Rational treatment development.
Most recent key publications
1: Behavioural disinhibition and antiepileptic treatment in childhood epilepsy: a retrospective cohort study. Diana C. van Tuijl, Rolf H.H. Groenwold, Chantal Vlaskamp, Jolien S. van Campen, Kees P.J. Braun, Floor E. Jansen,, U, Bruining H. Epilepsia Open, 2017.
2: van Campen S, Jansen FE, Kleinrensink, NJ, Joëls M, Braun KPJ, Bruining H. Sensory Modulation Disorders in Childhood Epilepsy. Journal of Neurodevelopmental Disorders, 2016.
3: Bruining H, Passtoors L, Goriounova N, et al. Paradoxical benzodiazepine response: a rationale for bumetanide in neurodevelopmental disorders? Pediatrics, 2015.
4: Bruining H, Matsui A, Oguro-Ando A, Kahn R, et al. Genetic mapping in mice reveals the involvement of Pcdh9 in long-term social and object recognition, and sensorimotor development. Biological Psychiatry, 2015.
5: Behavioral signatures related to genetic disorders in autism. Bruining H, Eijkemans MJ, Kas MJ, Curran SR, Vorstman JA, Bolton PF. Mol Autism, 2014.
Fellowship and Awards
2017 Zon MW. TOP subsidy, 675kE, co PI.
2016 Dutch Brain Society. Sooner Better Treatment program, 300kE PI.
2015 ZonMW. Rational Pharmacotherapy Program (GGG) program, 327kE PI.
2015 Stichting Michelle foundation. Research in Tuberous Sclerosis, 30kE PI.
2012 Annual research prize of the Dutch Association for Autism for best scientific contribution.
2012 EMBO short-term fellowship.
2011 Personal fellowship from the Dr. J.L. Dobberke Foundation for research at Osaka University.