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Dr. JMPJ (Hans) Breur

During the past decades, the care for patients with congenital heart disease (CHD) has improved dramatically. Where only a minority of patients survived fifty years ago, currently more than 90% of patients live into adulthood. Therefor both research and clinical care need to shift from improving  mortality to reducing morbidity. To accomplish this we developed the Congenital Heart Disease life span project. This life cycle program investigates the origin of heart failure and neurocognitive impairment and tries to significantly reduce it. We focus on excellent surgical, percutaneous and medical interventions and follow-up in children with severe CHD. Furthermore, we are the first to have developed a neurodevelopmental follow-up program with MRI including fetal, pre-operative and post-operative MRI scans of the heart and brain. The program uses state of the art invasive and non-invasive imaging to enhance early detection and treatment of cardiac failure. This program is extensively supported by patient organizations and other stakeholders.

Contact

Email: h.breur@umcutrecht.nl

Phone: 0887555459

Keywords:

Congenital heart disease,  Neurodevelopmental outcome, Long term follow-up, Percutaneous treatment (of congenital heart disease), Whole Genome Sequencing (in congenital heart disease)

Research topic

  • Long term neurodevelopmental outcome and neuroprotection in congenital heart disease
  • 3D guided percutaneous interventions in congenital heart disease
  • Genetic origin of congenital heart disease

Type of research

  • Clinical trials
  • Cohort studies
  • Whole Genome Sequencing (WGS) in congenital heart disease

Collaborations / partnerships

  • European ABC consortium (EU Association on Brain and Congenital Heart disease):     (London (UCL/Evelina), Zurich, Giessen, Utrecht)
  • Hospital for Sick Children, Toronto, Canada (neurodevelopmental outcome in CHD)
  • Hubrecht institute
  • Policlinico San Donato Milan (Advanced imaging during percutaneous interventions)

Links Public Private Partners:

Pure Profile

Hans Breur

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